14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics

Volume 20 of the series IFMBE Proceedings pp 23-25

Electrically Charged Hydroxyapatite Enhances Immobilization and Proliferation of Osteoblasts

  • Yuri DekhtyarAffiliated withInstitute of Biomedical Engineering and Nanotechnologies, Riga Technical University Email author 
  • , N. PolyakaAffiliated withInstitute of Biomedical Engineering and Nanotechnologies, Riga Technical University
  • , R. SammonsAffiliated withSchool of Dentistry, St Chad’s Queensway, University of Birmingham

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Hydroxyapatite (HAP) is in use to fabricate implants in dentistry and orthopaedy. To functionalise a surface of the HAP that has a direct contact to the human cells a surface electrical charge deposition is employed. The current technologies can not provide uniformity of the charge for contrarily situated surfaces.

To overcome such the disadvantage a HAP hydrogenation technology has been reached. As the result the surface charge has been engineered.

The charge was estimated owing to measurements of the photoelectron emission work function. The later was increased to ∼ 0.2 eV.

The negatively charged HAP surface in contrast with the uncharged one attached 10 times more osteoblatic cells and increased their proliferation capacity in 1.6 time


implant hydroxyapatite electrical charge immobilisation proliferation