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The Neurogenic Hypothesis in Segmental Vitiligo

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Vitiligo

Abstract

An abnormal effect of neurohormones and neuropep-tides has been speculated to explain the chronic melano-cyte loss in vitiligo, especially in SV due to its distribution, which can fit dermatomes. The neural/neurogenic theory is supported by clinical, histological, ultrastructural, experimental, pathophysiological, and biochemical arguments. Those will be reviewed with emphasis on SV.

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Author information

Authors and Affiliations

  1. Service de Dermatologie, Hôpital Saint-André, CHU de Bordeaux, France

    Yvon Gauthier M.D

  2. Department of Dermatology, CHU Ibn Sina, Rabat, Maroc

    Laila Benzekri M.D, Ph.D

Authors
  1. Yvon Gauthier M.D
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  2. Laila Benzekri M.D, Ph.D
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Corresponding author

Correspondence to Yvon Gauthier M.D .

Editor information

Editors and Affiliations

  1. Istituto Dermatologico San Gallicano, via Elio Chianesi 53, Roma, 00144, Italy

    Mauro Picardo

  2. Service de Dermatologie De Dermatologie Pédiatrique, Centre de référence des maladies rares de la Peau Hôpital Saint-André, 1 rue Jean Burguet, Bordeaux, 33000, France

    Alain Taïeb

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© 2010 Springer-Verlag Berlin Heidelberg

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Gauthier, Y., Benzekri, L. (2010). The Neurogenic Hypothesis in Segmental Vitiligo. In: Picardo, M., Taïeb, A. (eds) Vitiligo. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69361-1_34

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  • DOI: https://doi.org/10.1007/978-3-540-69361-1_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69360-4

  • Online ISBN: 978-3-540-69361-1

  • eBook Packages: MedicineMedicine (R0)

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