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Histopathology

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Vitiligo

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References

  1. Ackerman AB, Chongchinant N, Sanchez J et al (1997) Histologic diagnosis of inflammatory skin diseases. An algorithmic method based on pattern analysis, 2nd edn. Williams &Wilkins, Baltimore, MD

    Google Scholar 

  2. Ackerman AB, Kerl H, Sánchez J (2000) A clinical atlas of 101 common skin diseases (with histopathologic correlation), 1st edn. Ardor Scribendi, New York, pp 645–650

    Google Scholar 

  3. Ahn SK, Choi EH, Lee SH et al (1994) Immunohistochemical studies from vitiligo—comparison between active and inactive lesions. Yonsei Med J 35:404–410

    PubMed  CAS  Google Scholar 

  4. Al Badri AMT, Todd PM, Garioch JJ et al (1993). An immuno-logical study of cutaneous lymphocytes in vitiligo. J Pathol 170:149–155

    Article  Google Scholar 

  5. Attili VR, Attili SK (2008) Lichenoid inflammation in vitiligo—a clinical and histopathologic review of 210 cases. Int J Dermatol 47:663–669

    Article  PubMed  Google Scholar 

  6. Bhawan J, Bhutani LK (1983) Keratinocyte damage in viti-ligo. J Cutan Pathol 10:207–212

    Article  PubMed  CAS  Google Scholar 

  7. Clarkson KS, Sturdgess IC, Molyneux AJ (2001) The usefulness of tyrosinase in the immunohistochemical assessment of melanocytic lesions: a comparison of the novel T311 antibody (anti-tyrosinase) with S-100, HMB45, and A103(anti-melan-A). J Clin Pathol 54:196–200

    Article  PubMed  CAS  Google Scholar 

  8. Dean NR, Brennan J, Haynes J et al (2002) Immuno-histochemical labelling of normal melanocytes. Appl Immu-nohistochem Mol Morphol 10:199–204

    Article  CAS  Google Scholar 

  9. El-Darouti MA, Marzouk SA, Azzam O et al (2006) Vitiligo vs. hypopigmented mycosis fungoides (histopathological and immunohistochemical study, univariate analysis). Eur J Dermatol 16:17–22

    PubMed  Google Scholar 

  10. Gokhale BB, Mehta LN (1983) Histopathology of vitiligi-nous skin. Int J Dermatol 22:477–480

    Article  PubMed  CAS  Google Scholar 

  11. Hann SK, Kim YS, Yoo JH (2000) Clinical and histopatho-logic characteristics of trichrome vitiligo. J Am Acad Dermatol 242:589–596

    Google Scholar 

  12. Hann SK, Park YK, Lee KG et al (1992) Epidermal changes in active vitiligo. J Dermatol 19:217–222

    PubMed  CAS  Google Scholar 

  13. Horn TD, Abanmi A (1997) Analysis of the lymphocytic infil-trate in a case of vitiligo. Am J Dermatopathol 19:400–402

    Article  PubMed  CAS  Google Scholar 

  14. Kao CH, Yu HS (1990) Depletion and repopulation of Langerhans cells in nonsegmental type vitiligo. J Dermatol 17:287–96

    PubMed  CAS  Google Scholar 

  15. Kim YC, Kim YJ, Kang HY et al (2008) Histopathologic features in vitiligo. Am J Dermatopathol 30:112–116

    Article  PubMed  Google Scholar 

  16. Koranne RV, Sachdeva KG (1988) Vitiligo. Int J Dermatol 27:676–681

    Article  PubMed  CAS  Google Scholar 

  17. Kovacs SO (1998) Vitiligo. J Am Acad Dermatol 38:647–666

    Article  PubMed  CAS  Google Scholar 

  18. Lee HS, Chun YS, Hann SK (1999) Nevus depigmentosus: clinical features and histopathologic characteristics in 67 patients. J Am Acad Dermatol 40:21–26

    Article  PubMed  CAS  Google Scholar 

  19. Le Poole IC, Van den Wijngaard RM, Westerhof W et al (1996) Presence of T-cells and macrophages in inflamma-tory vitiligo skin parallels melanocyte disappearance. Am J Pathol 148:1219–1228

    PubMed  Google Scholar 

  20. Le Poole IC, Van den Wijngaard RM, Westerhof W et al (1993) Presence or absence of melanocytes in vitiligo lesions: an immunohistochemical investigation. J Invest Dermatol 100:816–822

    Article  PubMed  Google Scholar 

  21. Moellmann G, Klein-Angerer S, Scollay DA et al (1982) Extracellular granular material and degeneration of kerati-nocytes in the normally pigmented epidermis of patients with vitiligo. J Invest Dermatol 79:321–330

    Article  PubMed  CAS  Google Scholar 

  22. Montes LF, Abulafia J, Wilborn WH et al (2003) Value of histopathology in vitiligo. Int J Dermatol 42:57–61

    Article  PubMed  Google Scholar 

  23. Mosher DB, Fitzpatrick TB, Ortonne JB et al (1999) Hypomelanoses and hypermelanoses. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB et al (eds) Dermatology in general medicine, 5th edn. McGraw-Hill, New York, pp 945–1017

    Google Scholar 

  24. Mosher DB, Fitzpatrick TB, Ortonne JB et al (1999) Normal skin color and general considerations of pigmentary disorders. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB et al (eds) Dermatology in general medicine, 5th edn. McGraw-Hill, New York, pp 936–944

    Google Scholar 

  25. Murphy FG (2005) Histology of the skin. In: Elder D, Elenitsas R, Jaworsky C, Johnson B (eds) Lever's histopathology of the skin, 9th edn. Lipincott Williams&Wilkins, Philadelphia, pp 16–17

    Google Scholar 

  26. Pretti Aslanian FM, Noe RA, Cuzzi T et al (2007) Abnormal histological findings in active vitiligo include the normal-appearing skin. Pigment Cell Res 20:144–145

    Article  PubMed  Google Scholar 

  27. Sharquie KE, Mehenna SH, Naji AA et al (2004) Inflammatory changes in vitiligo. Stage I and II depigmenta-tion. Am J Dermatopathol 26:108–112

    Article  Google Scholar 

  28. Spielvogel RL, Kantor GR (1997) Pigmentary disorders of the skin. In: Elder D, Elenitsas R, Jaworsky C et al (eds) Lever's histopathology of the skin, 8th edn. Lipincott-Raven, Philadelphia, pp 617–623

    Google Scholar 

  29. Tretiakova MS, Shea CR, Petronic-Rosic VM (2006) Decreased CD117 expression in hypopigmented mycosis fungoides correlates with hypomelanosis: lessons learned from vitiligo. Mod Pathol 19:1255–1260

    Article  PubMed  Google Scholar 

  30. Van den Wijngaard R, Wañkowicz-Kaliñska A, Le Poole C et al (2000) Local immune response in skin of generalized vitiligo patients. Destruction of melanocytes is associated with the proeminent presence of CLA+T-cells at the perile-sional site. Lab Invest 80:1299–309

    Article  PubMed  Google Scholar 

  31. Wankowicz-Kalinska A, Van den Wijngaard RM, Tigges BJ et al (2003) Immunopolarization of CD4+ and CD8+ T-cells to type-1-like is associated with melanocyte loss in human vitiligo. Lab Invest 83:683–695

    PubMed  CAS  Google Scholar 

  32. Weedon D, Strutton G (2002) Disorders of pigmentation. Skin pathology, 2nd edn. Churchill Livingston, London, pp 321–341

    Google Scholar 

  33. Westerhof W, Groot I, Krieg SR et al (1986) Langerhans'cell population studies with OKT6 and HLA-DR monoclonal antibodies in vitiligo patients treated with oral phenylalanine loading and U VA irradiation. Acta Derm Venereol 66:259–262

    PubMed  CAS  Google Scholar 

  34. Wick MR (2006) Immunohistology of melanocytic neoplasms. In: Dabbs DJ (ed). Diagnostic immunohistochemis-try, 2nd edn. Churchill Livingstone, Pittsburgh, PA, pp 166–168

    Google Scholar 

  35. Wolff RK, Johnson RA, Surmond D (2005) Pigmentary disorders. In: Fitzpatrick's color atlas &synopsis of clinical dermatology, 5th edn. McGraw-Hill, New York, pp 336–343

    Google Scholar 

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Author information

Authors and Affiliations

  1. Federal University of Rio de Janeiro, Rio de Janeiro, Brasil

    Flávia Pretti Aslanian M.D, Ph.D

  2. Department of Dermatology, Federal University of Rio de Janeiro, Leblon, Rio de Janeiro, Brasil

    Absalom Filgueira M.D, Ph.D

  3. Federal University of Rio de Janeiro, Rio de Janeiro, Brasil

    Tullia Cuzzi M.D. Ph.D

  4. Department of Pathology, Hôpital du Haut Lév®que, Bordeaux, France

    Béatrice Vergier M.D.

Authors
  1. Flávia Pretti Aslanian M.D, Ph.D
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  2. Absalom Filgueira M.D, Ph.D
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  3. Tullia Cuzzi M.D. Ph.D
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  4. Béatrice Vergier M.D.
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Corresponding author

Correspondence to Flávia Pretti Aslanian M.D, Ph.D .

Editor information

Editors and Affiliations

  1. Istituto Dermatologico San Gallicano, via Elio Chianesi 53, Roma, 00144, Italy

    Mauro Picardo

  2. Service de Dermatologie De Dermatologie Pédiatrique, Centre de référence des maladies rares de la Peau Hôpital Saint-André, 1 rue Jean Burguet, Bordeaux, 33000, France

    Alain Taïeb

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Aslanian, F.P., Filgueira, A., Cuzzi, T., Vergier, B. (2010). Histopathology. In: Picardo, M., Taïeb, A. (eds) Vitiligo. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69361-1_3

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  • DOI: https://doi.org/10.1007/978-3-540-69361-1_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69360-4

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