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Bioprostheses: Are They the Future of Incisional/Acquired Hernia Repair?

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Recurrent Hernia

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Abstract

Our understanding of the pathobiology of hernia formation has grown tremendously in the past decade. Indeed, several well-designed, molecular-based studies have shown that many acquired hernias (e.g. direct inguinal hernia) as well as incisional hernias arise in the setting of measurable abnormalities in tissue healing — either in the production of the various types of collagen or in the remodeling and breakdown via matrix metalloproteinases [1, 2]. In addition, several well-conducted, long-term studies (>5 years follow-up) have shown that the rate of recurrences after primary autogenous repairs of incisional hernias is really much greater than we ever appreciated previously [3, 4].

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Author information

Authors and Affiliations

  1. Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN, 55902, USA

    M. G. Sarr

Authors
  1. M. G. Sarr
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  2. E. Podgaetz
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  3. J. S. Lane
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Editor information

Editors and Affiliations

  1. Chirurgische Klinik, Universitätsklinikum Aachen, Pauwelsstraße 30, 52074, Aachen, Germany

    Volker Schumpelick

  2. Department of Surgery, Creighton University, 601 North 30th Street Suite 3740, Omaha, NE, 68131, USA

    Robert J. Fitzgibbons

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© 2007 Springer-Verlag Berlin Heidelberg

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Sarr, M.G., Podgaetz, E., Lane, J.S. (2007). Bioprostheses: Are They the Future of Incisional/Acquired Hernia Repair?. In: Schumpelick, V., Fitzgibbons, R.J. (eds) Recurrent Hernia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68988-1_18

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  • DOI: https://doi.org/10.1007/978-3-540-68988-1_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-37545-6

  • Online ISBN: 978-3-540-68988-1

  • eBook Packages: MedicineMedicine (R0)

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