Abstract
Radiotherapy (RT) of malignant head and neck disorders is a common and widely accepted treatment option, and radiogenic toxicity — most importantly the reduced production of the saliva, the mucosal changes and the alteration of taste — is an accepted risk if the final aim is long-term local tumor control or even cure. The greater salivary glands are organs at risk in the daily routine of radiooncology. Thus, it appears exceptional to consider any RT indications for benign parotid disorders. The required RT doses should be well below the tolerance dose (TD) for xerostomia in long-term evaluation. Rubin estimated the tolerance dose for the occurrence of xerostomia to be 5% within 5 years after a conventionally fractionated RT course with a 2-Gy single dose and 50-Gy total dose (i.e., TD5/5) [21]; Emami et al. defined a TD5/5 dose value of 32 Gy assuming that more than one third of the parotid gland is irradiated [6]. RT of benign head and neck diseases provides an excellent opportunity to review the development of RT indications over a long period of time and possibly allows a revival of RT for special indications in the future.
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Further Reading
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Oppenkowski, R., Seegenschmiedt, M.H. (2008). Non-Malignant Disorders of the Head Region. In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_33
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DOI: https://doi.org/10.1007/978-3-540-68943-0_33
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