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Aggressive Fibromatosis/Desmoid Tumors

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Radiotherapy for Non-Malignant Disorders

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Desmoids are rare benign neoplasms of the connective tissue that arise from the deep muscle fascia, aponeuroses, tendons and scar tissue [14, 19, 29]. The Anglo-American literature describes them as “aggressive fibromatosis” [14, 32]. The disease has been known since the 19th century: The terms desmoid and desmoidfibrom were coined by the famous German physiologist and comparative anatomist Johannes Müller (1801-1858) from Berlin in 1838 [56]. The name is derived from ancient Greek and indicates a band-like appearance. In 1832, the surgeon John McFarlane from Glasgow was the first to mention the entity in the English-speaking literature. First neoplasms in the abdominal walls of women who recently had given birth were described [34]. Later, similar tumors were found in other anatomic regions. The term fibromatosis was introduced for the first time by Arthur Purdy Stout from New York [76]. He stated that desmoids are masses of proliferated, scar-like tissue, which in spite of the fact of tissue infiltration rarely recur (which is not true today!) and do not become true malignant neoplasms.

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Authors and Affiliations

  1. Department of Radiation Therapy and Radiation Oncology, Franziskus Hospital Bielefeld, Kiskerstrasse 26, 33615, Bielefeld, Germany

    Oliver Micke MD (PD)

  2. Department of Radiation Oncology, University of Cologne, Joseph-Stelzmann-Strasse 9, 50924, Cologne, Germany

    Hans T. Eich MD (PD)

  3. Department of Radiation Therapy and Oncology, Medical University Hannover, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany

    Frank Bruns MD

  4. Department of Radiation Therapy and Radiation Oncology, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany

    Jürgen Heide MD

  5. Department of General Orthopaedics, University Hospital Münster, Albert-Schweitzer-Strasse 33, 48149, Münster, Germany

    Georg Gosheger MD

  6. Dept. of Radiation Oncology and Therapeutic Radiology, Alfried Krupp Hospital, Alfried Krupp Straße 21, 45117, Essen, Germany

    Michael H. Seegenschmiedt MD (Professor)

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Editors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, Postfach 10 22 43, 45117, Essen, Germany

    Michael Heinrich Seegenschmiedt MD (Professor) (Professor)

  2. Strahlenklinik Klinikum Duisburg, Zu den Rehwiesen 9, 47055, Duisburg, Germany

    Hans-Bruno Makoski MD (Professor) (Professor)

  3. Department of Radiation Biology, St. Bartolomew’s Medical College, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott MD (Professor) (Professor)

  4. Hylda Cohn/American Cancer Society, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

  5. College of Medicine, Drexel University, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

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Micke, O., Eich, H.T., Bruns, F., Heide, J., Gosheger, G., Seegenschmiedt, M.H. (2008). Aggressive Fibromatosis/Desmoid Tumors. In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_12

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