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Other Tests in Glaucoma: Genetic Testing

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Pearls of Glaucoma Management

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Abstract

One of the goals of human genetic research is to develop novel diagnostic and screening tests based on the identification of the genes responsible for the disease. Over the past decade ten genes have been shown to contribute to various forms of human ­glaucoma including: primary open angle glaucoma (MYOC, OPTN, WDR36, OPA1), glaucoma associated with Axenfeld–Rieger syndrome and other anterior segment dysgenesis disorders (FOXC1, PITX2, PAX6, LMX1B), congenital glaucoma (CYP1B1), and most recently pseudoexfoliation glaucoma (LOXL1) [1–5].

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Authors and Affiliations

  1. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, USA

    Janey L. Wiggs

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  1. Janey L. Wiggs
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Correspondence to Janey L. Wiggs .

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Editors and Affiliations

  1. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    JoAnn A. Giaconi

  2. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    Simon K. Law

  3. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    Anne L. Coleman

  4. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    Joseph Caprioli

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Wiggs, J.L. (2010). Other Tests in Glaucoma: Genetic Testing. In: Giaconi, J., Law, S., Coleman, A., Caprioli, J. (eds) Pearls of Glaucoma Management. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68240-0_18

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  • DOI: https://doi.org/10.1007/978-3-540-68240-0_18

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  • Print ISBN: 978-3-540-68238-7

  • Online ISBN: 978-3-540-68240-0

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