Abstract
Although mitochondria have been studied for nearly a century, and their role as the “power houses” of the aerobic cell has been recognised for twenty years, the mode of replication of these very important subcellular organelles is by no means clearly understood. Research effort in the area of mitochondrial biogenesis is at present intense and is increasing rapidly along the interconnected lines of biochemistry, cytology, genetics and molecular biology. Numerous review articles have recently appeared on the subject (e.g. Work, Coote, and Ashwell, 1968; Roodyn, 1968; Lloyd, 1969; Wagner, 1969) as well as at least two books (Roodyn and Wilkie, 1968; and Slater, Tager, Papa, and Quagliariello, 1968) and the reader is referred to these for detail and discussion in depth of the several aspects of the subject. The intention in this chapter is to trace the outline of our knowledge of mitochondrial genesis and continuity and to indicate how evidence from recent experiments is causing a continual modification of our understanding of how mitochondria are formed, and how they multiply.
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Baxter, R. (1971). Origin and Continuity of Mitochondria. In: Reinert, J., Ursprung, H. (eds) Origin and Continuity of Cell Organelles. Results and Problems in Cell Differentiation, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36396-5_2
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