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Treatment of Retinal Vein Occlusions

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Medical Retina

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

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References

  1. Aiello LP, Bursell SE, Clermont A et al (1997) Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-iso-form-selective inhibitor. Diabetes 46:1473–1480

    Article  PubMed  CAS  Google Scholar 

  2. Amirikia A, Scott IU, Murray TG et al (2001) Outcomes of vitreoretinal surgery for complications of branch retinal vein occlusion. Ophthalmology 108:372

    Article  PubMed  CAS  Google Scholar 

  3. Antoneti DA, Barber AJ, Hollinger LA et al (1999) Vascular endothelial growth factor induced rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. J Biol Chem 274:23463–23467

    Article  Google Scholar 

  4. Avitabile T, Longo A, Reibaldi A (2005) Intravitreal triamcinolone compared with macular laser grid photocoagulation for the treatment of cystoid macular edema. Am J Ophthalmol 140(4):695. e1–e8

    PubMed  CAS  Google Scholar 

  5. Bearelly S, Fekrat S (2004) Controversy in the management of retinal venous occlusive disease. Int Ophthalmol Clin 44(4):85–102

    Article  PubMed  Google Scholar 

  6. Bashshur ZF, Ma’luf RN, Allam S et al (2004) Intravitreal triamcinolone for the management of macular edema due to nonischemic central retinal vein occlusion. Arch Ophthalmol 122(8):1137–1140

    Article  PubMed  CAS  Google Scholar 

  7. Beer PM, Bakri SJ, Singh RJ et al (2003) Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology 110(4):681–686

    Article  PubMed  Google Scholar 

  8. Bowers DK, Finkelstein D, Wolff SM et al (1987) Branch retinal vein occlusion: a clinicopathological case report. Retina 7:252–259

    Article  PubMed  CAS  Google Scholar 

  9. Branch Vein Occlusion Study Group (1984) Argon laser photocoagulation for macular edema in branch vein occlusion. Am J Ophthalmol 98:271

    Google Scholar 

  10. Branch Vein Occlusion Study Group (1986) Argon laser scatter photocoagulation for prevention of neovascularization and vitreous hemorrhage in branch vein occlusion. A randomized clinical trial. Arch Ophthalmol 104:34

    Google Scholar 

  11. Browning DJ, Antoszyk AN (1998) Laser chorioretinal venous anastomosis for nonischemic central retinal vein occlusion. Ophthalmology 105(4):670–677; discussion 7–9

    Article  PubMed  CAS  Google Scholar 

  12. Browning D, Rotberg M (1996) Vitreous hemorrhage complicating laser-induced chorioretinal anastomosis for central retinal vein occlusion. Am J Ophthalmol 122(4):588–589

    PubMed  CAS  Google Scholar 

  13. Bynoe LA, Weiss JN (2003) Retinal endovascular surgery and intravitreal triamcinolone acetonide for central vein occlusion in young adults. Am J Ophthalmol 135(3):382–384

    Article  PubMed  CAS  Google Scholar 

  14. Cekic O, Chang S, Tseng J et al (2005) Intravitreal triamcinolone treatment for macular edema associated with central retinal vein occlusion and hemiretinal vein occlusion. Retina 25(7):846–850

    Article  PubMed  Google Scholar 

  15. Cekic O, Chang S, Tseng J et al (2005) Intravitreal triamcinolone injection for treatment of macular edema secondary to branch retinal vein occlusion. Retina 25(7):851–855

    Article  PubMed  Google Scholar 

  16. Central Vein Occlusion Study Group (1993) Baseline and early natural history report: the Central Vein Occlusion Study. Arch Ophthalmol 111:1087

    Google Scholar 

  17. Central Vein Occlusion Study Group (1995) Evaluation of grid pattern photocoagulation for macular edema in central vein occlusion: The Central Vein Occlusion Study Group M report. Ophthalmology 102: 1425

    Google Scholar 

  18. Central Vein Occlusion Study Group (1995) A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion: the Central Vein Occlusion Study Group N report. Ophthalmology 102:1434

    Google Scholar 

  19. Central Vein Occlusion Study Group (1997) Natural history and clinical management of central retinal vein occlusion: the Central Vein Occlusion Study Group. Arch Ophthalmol 115:486

    Google Scholar 

  20. Chen S, Sundaram V, Lochhead J, Patel C (2006) Intravitreal triamcinolone for treatment of ischemic macular edema associated with branch retinal vein occlusion. Am J Ophthalmol 141(5):876–883

    Article  PubMed  CAS  Google Scholar 

  21. Chopdar A (1984) Dual trunk central retinal vein incidence in clinical practice. Arch Ophthalmol 102:85

    PubMed  CAS  Google Scholar 

  22. Clemett RS (1974) Retinal branch vein occlusion: changes at the site of obstruction. Br J Ophthalmol 58:548–554

    Article  PubMed  CAS  Google Scholar 

  23. Duker JS, Brown GC (1989) Anterior location of the crossing artery in branch retinal vein occlusion. Arch Ophthalmol 107:998

    PubMed  CAS  Google Scholar 

  24. Dev S, Buckley EG (1999) Optic nerve sheath decompression for progressive central retinal vein occlusion. Ophthalmic Surg Lasers 30(3):181–184

    PubMed  CAS  Google Scholar 

  25. Elman MJ, Raden RZ, Carrigan A (2001) Intravitreal injection of tissue plasminogen activator for central retinal vein occlusion. Trans Am Ophthalmol Soc 99:219–221; discussion 22–23

    PubMed  CAS  Google Scholar 

  26. Eye Disease Case-Control Study Group (1993) Risk factors for branch retinal vein occlusion. Am J Ophthalmol 116:286–296

    Google Scholar 

  27. Eye Disease Case-Control Study Group (1996) Risk factors for central retinal vein occlusion. Arch Ophthalmol 114:545

    Google Scholar 

  28. Fekrat S, de Juan E Jr (1999) Chorioretinal venous anastomosis for central retinal vein occlusion: transvitreal venipuncture. Ophthalmic Surg Lasers 30(1):52–55

    PubMed  CAS  Google Scholar 

  29. Fekrat S, Finkelstein D (2001) Branch retinal vein occlusion disease. In: Schachat AP (2001) Retina, 3rd edn. Mosby, St. Louis

    Google Scholar 

  30. Fekrat S, Goldberg MF, Finkelstein D (1998) Laser-induced chorioretinal venous anastomosis for nonischemic central or branch retinal vein occlusion. Arch Ophthalmol 116(1):43–52

    PubMed  CAS  Google Scholar 

  31. Finkelstein D (1992) Ischemic macular edema: recognition and favorable natural history in branch vein occlusion. Arch Ophthalmol 119:1427–1434

    Google Scholar 

  32. Fong AC, Schatz H (1993) Central retinal vein occlusion in young adults. Surv Ophthalmol 38:88

    Article  Google Scholar 

  33. Francis PJ, Stanford MR, Graham EM (2003) Dehydration is a risk factor for central retinal vein occlusion in young patients. Acta Ophthalmol Scand 81(4):415–416

    Article  PubMed  Google Scholar 

  34. Frangieh GT, Green WR, Barraquer-Somers E et al (1982) Histopathologic study of nine branch retinal vein occlusions. Arch Ophthalmol 100:1132

    PubMed  CAS  Google Scholar 

  35. Garcia-Arumi J, Boixadera A, Martinez-Castillo V et al (2003) Chorioretinal anastomosis after radial optic neurotomy for central retinal vein occlusion. Arch Ophthalmol 121:1385–1391

    Article  Google Scholar 

  36. Glacet-Bernard A, Kuhn D, Vine AK et al (2000) Treatment of recent onset central retinal vein occlusion with intravitreal tissue plasminogen activator: a pilot study. Br J Ophthalmol 84(6):609–613

    Article  PubMed  CAS  Google Scholar 

  37. Ghazi NG, Noureddine BN, Haddad RS et al (2003) Intravitreal tissue plasminogen activator in the management of central retinal vein occlusion. Retina 23:780–784

    Article  PubMed  Google Scholar 

  38. Gottlieb JL, Blice JP, Mestichelli B et al (1998) Activated protein C resistance, factor V Leiden, and central retinal vein occlusion in young adults. Arch Ophthalmol 116:577–579

    PubMed  CAS  Google Scholar 

  39. Green W, Chan C, Hutchins G et al (1981) Central retinal vein occlusions: a prospective histopathologic study of 29 eyes in 28 cases. Retina 1:27

    PubMed  CAS  Google Scholar 

  40. Gutman FA (1983) Evaluation of a patient with central retinal vein occlusion. Ophthalmology 90(5):481–483

    PubMed  CAS  Google Scholar 

  41. Hattenbach LO, Steinkamp G, Scharrer I et al (1998) Fibrinolytic therapy with low-dose recombinant tissue plasminogen activator in retinal vein occlusion. Ophthalmologica 212(6):394–398

    Article  PubMed  CAS  Google Scholar 

  42. Hattenbach LO, Wellermann G, Steinkamp GW et al (1999) Visual outcome after treatment with low-dose recombinant tissue plasminogen activator or hemo-dilution in ischemic central retinal vein occlusion. Ophthalmologica 213(6):360–366

    Article  PubMed  CAS  Google Scholar 

  43. Hayreh SS, Hayreh MS (1980) Hemi-central retinal vein occlusion: pathogenesis, clinical features, and natural history. Arch Ophthalmol 98:1600

    PubMed  CAS  Google Scholar 

  44. Hayreh SS, Zimmerman MB, Podhajsky P (2002) Hematologic abnormalities associated with various types of retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 240(3):180–196

    Article  PubMed  Google Scholar 

  45. Hockley DJ, Tripathi RC, Ashton N (1979) Experimental branch vein occlusion in the rhesus monkeys. III. Br J Ophthalmol 63:393–411

    Article  CAS  Google Scholar 

  46. Hvarfner C, Hillarp A, Larsson J (2003) Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion. Br J Ophthalmol 87(3):305–306

    Article  PubMed  CAS  Google Scholar 

  47. Ip MS, Gottlieb JL, Kahana A et al (2004) Intravitreal triamcinolone for the treatment of macular edema associated with central retinal vein occlusion. Arch Ophthalmol 122(8):1131–1136

    Article  PubMed  CAS  Google Scholar 

  48. Iturralde D, Spaide RF, Meyerle CB et al (2006) Intravitreal bevacizumab (Avastin) treatment of macular edema in central retinal vein occlusion. Retina 26(3):279–284

    Article  PubMed  Google Scholar 

  49. Jaffe GJ et al (2005) Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis. Ophthalmology 112(7):1192–1198

    Article  PubMed  Google Scholar 

  50. Jonas JB (2002) Intravitreal triamcinolone acetonide as treatment of macular edema in central retinal vein occlusion. Graefes Arch Clin and Exp Ophthalmol 240(9):782–783

    Google Scholar 

  51. Jonas JB, Akkoyun I, Kamppeter B et al (2005) Branch retinal vein occlusion treated by intravitreal triamcinolone acetonide. Eye 19(1):65–71

    Article  PubMed  CAS  Google Scholar 

  52. Krepler K, Ergun E, Sacu S et al (2005) Intravitreal triamcinolone acetonide in patients with macular oedema due to central vein occlusion. Acta Ophthalmol Scand 83(1):71–75

    Article  PubMed  CAS  Google Scholar 

  53. Kumar B, Yu DY, Morgan WH et al (1998) The distribution of angioarchitectural changes within the vicinity of the arteriovenous crossing in branch retinal vein occlusion. Ophthalmology 105:424–427

    Article  PubMed  CAS  Google Scholar 

  54. Kurimoto M, Takagi H, Suzuma K (1999) Vitrectomy for macular edema secondary to retinal vein occlusion: evaluation by retinal thickness analyzer. Jpn J Ophthalmol 53:717

    Google Scholar 

  55. Kwok AK, Lee VY, Lai TY et al (2003) Laser induced chorioretinal venous anastomosis in ischaemic central retinal vein occlusion. Br J Ophthalmol 87(8):1043–1044

    Article  PubMed  CAS  Google Scholar 

  56. Lahey JM, Fong DS, Kearney J (1999) Intravitreal tissue plasminogen activator for acute central retinal vein occlusion. Ophthalmic Surg Lasers 30(6):427–434

    PubMed  CAS  Google Scholar 

  57. Lai JC, Mruthyunjaya P, Fekrat S (2002) Central retinal vein occlusion in patients on chronic Coumadin® anticoagulation. Invest Ophthalmol Vis Sci 42:ARVO E-Abstract 519

    Google Scholar 

  58. Lardenoye CWTA, Probst K, DeLint PJ et al (2000) Photoreceptor function in eyes with macular edema. Invest Ophthalmol Vis Sci 41(12):4048–4053

    PubMed  CAS  Google Scholar 

  59. Lee H, Shah GK (2005) Intravitreal triamcinolone as primary treatment of cystoid macular edema secondary to branch retinal vein occlusion. Retina 25(5):551–555

    Article  PubMed  Google Scholar 

  60. McCuen BW Jr, Bessler M, Tano Y et al (1981) The lack of toxicity of intravitreally administered triamcinolone acetonide. Am J Ophthalmol 91(6):785–788

    PubMed  CAS  Google Scholar 

  61. Mester U, Dillinger P (2000) Vitrectomy with decompression in branch retinal vein occlusion. Club Jules Gonin Meeting, Sicily

    Google Scholar 

  62. Nauck M, Karaklulakis G, Perruchoud AP et al (1998) Corticosteroids inhibit the expression of the vascular endothelial growth factor gene in human vascular smooth muscle cells. Eur J Pharmacol 341:309–315

    Article  PubMed  CAS  Google Scholar 

  63. Nauck M, Roth M, Tamm M et al (1997) Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is downregulated by corticosteroids. Am J Respir Cell Mol Biol 16:398–406

    PubMed  CAS  Google Scholar 

  64. Opremcak EM, Bruce RA (1999) Surgical decompression of branch retinal vein occlusion via arteriovenous crossing sheathotomy: a prospective review of 15 cases. Retina 19:1

    Article  PubMed  CAS  Google Scholar 

  65. Opremcak EM, Rehmar AJ, Ridenour CD et al (2006) Radial optic neurotomy with adjunctive intraocular triamcinolone for central retinal vein occlusion. Retina 26:306–313

    Article  PubMed  Google Scholar 

  66. Osterloh MD, Charles S (1988) Surgical decompression of branch retinal vein occlusions. Arch Ophthalmol 106:1469

    PubMed  CAS  Google Scholar 

  67. Park CH, Jaffe GJ, Fekrat S (2003) Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion. Am J Ophthalmol 136(3):419–425

    Article  PubMed  CAS  Google Scholar 

  68. Pe’er J, Folberg R, Itin A et al (1998) Vascular endothelial growth factor upregulation in human central retinal vein occlusion. Ophthalmology 105:412–416

    Article  PubMed  CAS  Google Scholar 

  69. Ramchandran RS, Jaffe GJ, Fekrat S et al (2006) Fluocinolone acetonide sustained drug delivery device for chronic retinal venous occlusive disease: 12 month results. ARVO Abstract

    Google Scholar 

  70. Roth DB, Chieh J, Spirn MJ et al (2003) Noninfectious endophthalmitis associated with intravitreal triamcinolone injection. Arch Ophthalmol 121(9):1279–1282

    Article  PubMed  Google Scholar 

  71. Saika S, Tanaka T, Miyamoto T (2001) Surgical posterior vitreous detachment combined with gas/air tamponade for treating macular edema associated with branch retinal vein occlusion: retinal tomography and visual outcome. Graefes Arch Clin Exp Ophthalmol 239:729

    PubMed  CAS  Google Scholar 

  72. Shah GK (2000) Adventitial sheathotomy for treatment of macular edema associated with branch retinal vein occlusion. Curr Opin Ophthalmol 11:171

    Article  PubMed  CAS  Google Scholar 

  73. Shah GK, Sharma S, Fineman MS et al (2000) Arteriovenous adventitial sheathotomy for the treatment of macular edema associated with branch retinal vein occlusion. Am J Ophthalmol 129:104

    Article  PubMed  CAS  Google Scholar 

  74. Shaikh S, Blumenkranz MS (2001) Transient improvement in visual acuity and macular edema in central retinal vein occlusion accompanied by in-flammatory features after pulse steroid and anti-inflammatory therapy. Retina 21(2):176–178

    Article  PubMed  CAS  Google Scholar 

  75. Tsujikawa A, Fujihara M, Iwawaki T et al (2005) Triamcinolone acetonide with vitrectomy for treatment of macular edema associated with branch retinal vein occlusion. Retina 25(7):861–867

    Article  PubMed  Google Scholar 

  76. Vasco-Posada J (1972) Modification of the circulation in the posterior pole of the eye. Ann Ophthalmol 4(1):48–59

    PubMed  CAS  Google Scholar 

  77. Vinores SA, Youssri AL, Luna JD et al (1997) Upregulation of vascular endothelial growth factor in ischemic and non-ischemic human and experimental retinal disease. Histol Histopathol 12:99–109

    PubMed  CAS  Google Scholar 

  78. Weinberg D, Dodwell DG, Fern SA (1990) Anatomy of arteriovenous crossings in branch retinal vein occlusion. Am J Ophthalmol 109:298–302

    PubMed  CAS  Google Scholar 

  79. Weiss JN, Bynoe LA (2001) Injection of tissue plasminogen activator into a branch retinal vein in eyes with central retinal vein occlusion. Ophthalmology 108(12):2249–2257

    Article  PubMed  CAS  Google Scholar 

  80. Weizer JS, Stinnett SS, Fekrat S (2003) Radial optic neurotomy as treatment for central retinal vein occlusion. Am J Ophthalmol 136(5):814–819

    Article  PubMed  Google Scholar 

  81. Williamson TH, O’Donnell A (2005) Intravitreal triamcinolone acetonide for cystoid macular edema in nonischemic central retinal vein occlusion. Am J Ophthalmol 139(5):860–866

    Article  PubMed  CAS  Google Scholar 

  82. Williamson TH, Rumley A, Lowe GD (1996) Blood viscosity, coagulation, and activated protein C resistance in central retinal vein occlusion: a population controlled study. Br J Ophthalmol 80(3):203–208

    Article  PubMed  CAS  Google Scholar 

  83. Wilson CA, Berkowitz BA, Sato Y et al (1992) Treatment with intravitreal steroid reduces blood-retinal barrier breakdown due to retinal photocoagulation. Arch Ophthalmol 110(8):1155–1159

    PubMed  CAS  Google Scholar 

  84. Wilson DJ, Finkelstein D, Quigley HA et al (1998) Macular grid photocoagulation: an experimental study on the primate retina. Arch Ophthalmol 106:100

    Google Scholar 

  85. Wolf S, Arend O, Bertram B et al (1994) Hemo-dilution therapy in central retinal vein occlusion: one-year results of a prospective randomized study. Graefes Arch Clin Exp Ophthalmol 232(1):33–39

    Article  PubMed  CAS  Google Scholar 

  86. Yepremyan, M et al (2005) Early treatment of cystoid macular edema secondary to branch retinal vein occlusion with intravitreal triamcinolone acetonide. Ophthalmic Surg Lasers Imaging 36(1):30–36

    PubMed  Google Scholar 

  87. Zhao J, Sastry SM, Sperduto RD et al (1993) Arteriovenous crossing patterns in branch retinal vein occlusion. The Eye Disease Case-Control Study Group. Ophthalmology 100:423–428

    CAS  Google Scholar 

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  1. Department of Ophthalmology, Duke University Medical Center, Durham, NC, 27710, USA

    Rajeev S. Ramchandran MD, R. Keith Shuler MD & Sharon Fekrat MD, FACS

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  1. Rajeev S. Ramchandran MD
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  2. R. Keith Shuler MD
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  3. Sharon Fekrat MD, FACS
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Editors and Affiliations

  1. Department of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127, Bonn, Germany

    Frank G. Holz MD (Professor of Ophthalmology) (Professor of Ophthalmology)

  2. Vitreous, Retina, and Macula Consultants of New York, and LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, 460 Park Avenue, New York, NY, 10022, USA

    Richard F. Spaide MD (Assistent Clinical Professor) (Assistent Clinical Professor)

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Ramchandran, R.S., Shuler, R.K., Fekrat, S. (2007). Treatment of Retinal Vein Occlusions. In: Holz, F.G., Spaide, R.F. (eds) Medical Retina. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-33672-3_10

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