Skip to main content

Ductal Carcinoma In Situ: a Modern Approach to Patient Management

  • Chapter
Breast Cancer and Molecular Medicine
  • 1014 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Morrow, M. et al. Standard for the management of ductal carcinoma in situ of the breast (DCIS). CA Cancer J Clin 52, 256–76 (2002).

    Article  PubMed  Google Scholar 

  2. Schnitt, S. J. & Connolly, J. L. Classification of ductal carcinoma in situ: striving for clinical relevance in the era of breast conserving therapy. Hum Pathol 28, 877–80 (1997).

    Article  PubMed  CAS  Google Scholar 

  3. Allred, D. C., O’Connell, P., Fuqua, S. A. & Osborne, C. K. Immunohistochemical studies of early breast cancer evolution. Breast Cancer Res Treat 32, 13–8 (1994).

    Article  PubMed  CAS  Google Scholar 

  4. Vicini, F. A. et al. Relationship between excision volume, margin status, and tumor size with the development of local recurrence in patients with ductal carcinoma-in-situ treated with breast-conserving therapy. J Surg Oncol 76, 245–54 (2001).

    Article  PubMed  CAS  Google Scholar 

  5. Silverstein, M. J. et al. The influence of margin width on local control of ductal carcinoma in situ of the breast. N Engl J Med 340, 1455–61 (1999).

    Article  PubMed  CAS  Google Scholar 

  6. Hetelekidis, S. et al. Predictors of local recurrence following excision alone for ductal carcinoma in situ. Cancer 85, 427–31 (1999).

    Article  PubMed  CAS  Google Scholar 

  7. Fisher, E. R. et al. Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma. Cancer 86, 429–38 (1999).

    Article  PubMed  CAS  Google Scholar 

  8. Jensen, R. A. & Page, D. L. Ductal carcinoma in situ of the breast: impact of pathology on therapeutic decisions. Am J Surg Pathol 27, 828–31 (2003).

    Article  PubMed  Google Scholar 

  9. Ernster, V. L. Prophylactic mastectomy in women with a high risk of breast cancer. N Engl J Med 340, 1838; discussion 1839 (1999).

    PubMed  CAS  Google Scholar 

  10. Ernster, V. L., Barclay, J., Kerlikowske, K., Grady, D. & Henderson, C. Incidence of and treatment for ductal carcinoma in situ of the breast. JAMA 275, 913–8 (1996).

    Article  PubMed  CAS  Google Scholar 

  11. Harris, J. R. e. in Breast Dis (2000).

    Google Scholar 

  12. von Rueden, D. G. & Wilson, R. E. Intraductal carcinoma of the breast. Surg Gynecol Obstet 158, 105–11 (1984).

    Google Scholar 

  13. Schuh, M. E., Nemoto, T., Penetrante, R. B., Rosner, D. & Dao, T. L. Intraductal carcinoma. Analysis of presentation, pathologic findings, and outcome of disease. Arch Surg 121, 1303–7 (1986).

    Article  PubMed  CAS  Google Scholar 

  14. Kinne, D. W. et al. Breast carcinoma in situ. Arch Surg 124, 33–6 (1989).

    PubMed  CAS  Google Scholar 

  15. Kerlikowske, K. et al. Characteristics associated with recurrence among women with ductal carcinoma in situ treated by lumpectomy. J Natl Cancer Inst 95, 1692–702 (2003).

    PubMed  Google Scholar 

  16. Wong, J., Gadd, MA, Gelman, R, Kaelin, CM, Lester S, Schnitt, SJ, Sgroi, DC, Smith, BL, Troyan SL, Harris, JR. Wide Excision Alone for Ductal Carcinoma In Situ (DCIS) of the Breast. Breast Cancer Res Treat 82, Abstract 15 (2003).

    Google Scholar 

  17. Silverstein, M. J. & Buchanan, C. Ductal carcinoma in situ: USC/Van Nuys Prognostic Index and the impact of margin status. Breast 12, 457–71 (2003).

    Article  PubMed  Google Scholar 

  18. Waldman, F. M. et al. Chromosomal alterations in ductal carcinomas in situ and their in situ recurrences. J Natl Cancer Inst 92, 313–20 (2000).

    Article  PubMed  CAS  Google Scholar 

  19. Deng, G., Lu, Y., Zlotnikov, G., Thor, A. D. & Smith, H. S. Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 274, 2057–9 (1996).

    Article  PubMed  CAS  Google Scholar 

  20. Ohtake, T. et al. Computer-assisted complete three-dimensional reconstruction of the mammary ductal/lobular systems: implications of ductal anastomoses for breast-conserving surgery. Cancer 91, 2263–72 (2001).

    Article  PubMed  CAS  Google Scholar 

  21. Ohtake, T. et al. Intraductal extension of primary invasive breast carcinoma treated by breast-conservative surgery. Computer graphic three-dimensional reconstruction of the mammary duct-lobular systems. Cancer 76, 32–45 (1995).

    Article  PubMed  CAS  Google Scholar 

  22. Crowe, J. P., Jr. et al. Nipple-sparing mastectomy: technique and results of 54 procedures. Arch Surg 139, 148–50 (2004).

    Article  PubMed  Google Scholar 

  23. Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists’ Collaborative Group. Lancet 351, 1451–67 (1998).

    Article  Google Scholar 

  24. Fisher, B. et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 90, 1371–88 (1998).

    Article  PubMed  CAS  Google Scholar 

  25. Allred, D. C., Bryant, J., Land, S., Paik, S., Fisher, E., Julian, T., Margolese, R., Smith, R., Mamounas, T., Osborne, C.K., Fisher, B., Wolmark, N. Estrogen Receptor Expression as a Predictive Marker of the Effectiveness of Tamoxifen: Findings from the NSABP Protocol B-24. Breast Cancer Res Treat 76, Abstract 30 (2002).

    Google Scholar 

  26. Houghton, J. et al. Radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial. Lancet 362, 95–102 (2003).

    Article  PubMed  Google Scholar 

  27. Baum, M. et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 359, 2131–9 (2002).

    Article  PubMed  CAS  Google Scholar 

  28. Goss, P. E. et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 349, 1793–802 (2003).

    Article  PubMed  CAS  Google Scholar 

  29. Mamounas, E., J. Bryant, et al. Primary breast cancer as a risk factor for subsequent contralateral breast cancer: NSABP experience from nine randomized adjuvant trials. Breast Cancer Res Treat 50, 227–346 (1998).

    Google Scholar 

  30. Wolmark, N. (1998).

    Google Scholar 

  31. Silverstein, M. J. et al. Outcome after invasive local recurrence in patients with ductal carcinoma in situ of the breast. J Clin Oncol 16, 1367–73 (1998).

    PubMed  CAS  Google Scholar 

  32. Welch, H. G. Should I be Tested for Cancer? (University of California Press, 2004).

    Google Scholar 

  33. Esserman, L., Sepucha, K., Ozanne, E. & Hwang, E. S. Applying the neoadjuvant paradigm to ductal carcinoma in situ. Ann Surg Oncol 11, 28S–36S (2004).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Esserman, L., Park, C. (2006). Ductal Carcinoma In Situ: a Modern Approach to Patient Management. In: Piccart, M.J., Hung, MC., Solin, L.J., Cardoso, F., Wood, W.C. (eds) Breast Cancer and Molecular Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-28266-2_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-28266-2_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-28265-5

  • Online ISBN: 978-3-540-28266-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics