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Reverse TME: The “Bottom-UP” Approach to Low Rectal Cancer

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Comprehensive Rectal Cancer Care

Abstract

Colorectal cancer is the third most common type of cancer diagnosed in United States, and with rectal cancer accounting for approximately the 30% of the cases. In 2016, the American Cancer Society estimated almost 40,000 of new rectal cancer cases, the majority undergoing surgery – a surgery that has traditionally been difficult, especially in cases of obesity, males and with narrow pelvis. The oncologic cornerstone of this surgery is the removal of the mesorectum as an intact specimen en-bloc with a margin-free tumour. Systematic adherence to this principle has been proven to prolong survival and reduce locoregional recurrence.

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References

  1. Sylla P, Rattner DW, Delgado S, Lacy AM. NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance. Surg Endosc. 2010;24:1205–10.

    Article  Google Scholar 

  2. Buess G, Kipfmüller K, Hack D, et al. Technique of transanal endoscopic microsurgery. Surg Endosc. 1988;2(2):71–5.

    Article  CAS  Google Scholar 

  3. Marks GJ, Marks JH, Mohiuddin M, et al. Radical sphincter preservation surgery with coloanal anastomosis following high-dose external irradiation for the very low lying rectal cancer. Recent Results Cancer Res. 1998;146:161–74.

    Article  CAS  Google Scholar 

  4. Whiteford MH, Denk PM, Swanstrom LL. Feasibility of radical sigmoid colectomy performed as natural orifice translumenal endoscopic surgery (NOTES) using transanal endoscopic microsurgery. Surg Endosc. 2007;21:1870–4.

    Article  CAS  Google Scholar 

  5. Atallah S, Larach S, Albert M. Transanal minimally invasive surgery: a giant leap forward. Surg Endosc. 2010;24:2200–5.

    Article  Google Scholar 

  6. Heald RJ. A new approach to rectal cancer. Br J Hosp Med. 1979;22:277–28.

    CAS  PubMed  Google Scholar 

  7. Green BL, Marshall HC, Collinson F, et al. Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg. 2013;100(1):75–82.

    Article  CAS  Google Scholar 

  8. Guillou PJ, Quirke P, Thorpe H, et al. MRC CLASICC trial group. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet. 2005;365(9472):1718–26.

    Article  Google Scholar 

  9. van der Pas MH, Haglind E, Cuesta MA, et al. COlorectal cancer Laparoscopic or Open Resection II (COLOR II) Study Group. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol. 2013;14(3):210–8.

    Article  Google Scholar 

  10. Kang SB, Park JW, Jeong SY, et al. Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial. Lancet Oncol. 2010;11:637–45.

    Article  Google Scholar 

  11. Kim JS, Cho SY, Min BS, et al. Risk factors for anastomotic leakage after laparoscopic intracorporeal colorectal anastomosis with a double stapling technique. J Am Coll Surg. 2009;209(6):694–701.

    Article  Google Scholar 

  12. Schiessel R, Karner-Hanusch J, Herbst F, et al. Intersphincteric resection for low rectal tumours. Br J Surg. 1994;81(9):1376–8.

    Article  CAS  Google Scholar 

  13. Akagi Y, Shirouzu K, Ogata Y, et al. Oncologic outcomes of intersphincteric resection without preoperative chemoradiotherapy for very low rectal cancer. Surg Oncol. 2013;22(2):144–9.

    Article  Google Scholar 

  14. Marks G, Mohiuddin M, Goldstein SD. Sphincter preservation for cancer of the distal rectum using high dose preoperative radiation. Int J Radiat Oncol Biol Phys. 1988;15(5):1065–8.

    Article  CAS  Google Scholar 

  15. Tasende MM, Delgado S, Jimenez M, et al. Minimal invasive surgery: NOSE and NOTES in ulcerative colitis. Surg Endosc. 2015;29:3313–8.

    Article  Google Scholar 

  16. Bravo R, Fernández-Hevia M, Jiménez-Toscano M, et al. Transanal Hartmann reversal: a new technique. Surg Endosc. 2016;30(6):2628–31.

    Google Scholar 

  17. Borstlap WA, Harran N, Tanis PJ, Bemelman WA. Feasibility of the TAMIS technique for redo pelvic surgery. Surg Endosc. 2016;30(12):5364–71.

    Article  CAS  Google Scholar 

  18. Jafari MD, Wexner SD, Martz JE, et al. Perfusion assessment in laparoscopic left-sided/anterior resection (PILLAR II): a multi-institutional study. J Am Coll Surg. 2015;220(1):82–92.

    Article  Google Scholar 

  19. Rouanet P, Mourregot A, Azar CC, et al. Transanal endoscopic proctectomy: an innovative procedure for difficult resection of rectal tumors in men with narrow pelvis. Dis Colon Rectum. 2013;56:408–15.

    Article  Google Scholar 

  20. Simillis C, Hompes R, Penna M, et al. A systematic review of transanal total mesorectal excision: is this the future of rectal cancer surgery? Color Dis. 2016;18(1):19–36.

    Article  CAS  Google Scholar 

  21. Velthuis S, Veltcamp Helbach M, Tuynman JB, et al. Intra-abdominal bacterial contamination in TAMIS total mesorectal excision for rectal carcinoma: a prospective study. Surg Endosc. 2015;29(11):3319–23.

    Article  Google Scholar 

  22. Nagtegaal ID, van de Velde CJH, van der Worp E, et al. Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol. 2002;20:1729–37.

    Article  Google Scholar 

  23. Tuech JJ, Karoui M, Lelong B, et al. A step toward NOTES total mesorectal excision for rectal cancer. Endoscopic transanal proctectomy. Ann Surg. 2015;261:228–33.

    Article  Google Scholar 

  24. Veltcamp Helbach M, Deijen CL, Velthuis S, et al. Transanal total mesorectal excision for rectal adenocarcinoma: short-term outcomes and experience after 80 cases. Surg Endosc. 2016;30(2):464–70.

    Article  CAS  Google Scholar 

  25. Lacy AM, Tasende MM, Delgado S, et al. Transanal total mesorectal excision for rectal cancer: outcome after 140 patients. J Am Coll Surg. 2015;221(2):415–23.

    Article  Google Scholar 

  26. Elmore U, Fumagalli Romario U, Vignali A, et al. Laparoscopic anterior resection with transanal total mesorectal excision for rectal cancer: preliminary experience and impact on postoperative bowel function. J Laparoendosc Adv Surg Tech A. 2015;25(5):364–9.

    Article  Google Scholar 

  27. Zhang H, Zhang YS, Jin XW, et al. Transanal single-port laparoscopic total mesorectal excision in the treatment of rectal cancer. Tech Coloproctol. 2013;17:117–23.

    Article  CAS  Google Scholar 

  28. Chouillard E, Chahine E, Khoury G, et al. Notes total mesorectal excision (TME) for patients with rectal neoplasia: a preliminary experience. Surg Endosc. 2014;28:3150–7.

    Article  CAS  Google Scholar 

  29. Leroy J, Barry BD, Melani A, et al. No-scar transanal total mesorectal excision: the last step to pure NOTES for colorectal surgery. JAMA Surg. 2013;148:226–30; discussion 31.

    Google Scholar 

  30. Collinson FJ, Jayne DG, Pigazzi A, et al. An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer. Int J Color Dis. 2012;27(2):233–41.

    Article  Google Scholar 

  31. Huscher CG, Bretagnol F, Ponzano C. Robotic-assisted transanal total mesorectal excision: the key against the Achilles’ heel of rectal cancer. Ann Surg. 2015;261(5):e120–1.

    Article  Google Scholar 

  32. Gómez Ruiz M, Parra IM, Palanzuelos CM, et al. Robotic-assisted laparoscopic transanal total mesorectal excision for rectal cancer: a prospective pilot study. Dis Colon Rectum. 2015;58(1):145–53.

    Article  Google Scholar 

  33. Atallah S, Nassif G, Polavarapu H, et al. Robotic-assisted transanal surgery for total mesorectal excision (RATS-TME): a description of a novel surgical approach with video demonstration. Tech Coloproctol. 2013;17(4):441–7.

    Article  CAS  Google Scholar 

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Correspondence to Antonio M. Lacy .

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Arroyave, M.C., de Lacy, F.B., Lacy, A.M. (2019). Reverse TME: The “Bottom-UP” Approach to Low Rectal Cancer. In: Kwaan, M., Zbar, A. (eds) Comprehensive Rectal Cancer Care. Springer, Cham. https://doi.org/10.1007/978-3-319-98902-0_10

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  • DOI: https://doi.org/10.1007/978-3-319-98902-0_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98901-3

  • Online ISBN: 978-3-319-98902-0

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