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Phototherapy and Photochemotherapy

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Evidence-Based Psoriasis

Part of the book series: Updates in Clinical Dermatology ((UCD))

Abstract

Phototherapy and photochemotherapy have remained cornerstones in the management of psoriasis and other cutaneous conditions for more than 3000 years. Currently, ultraviolet (UV)-based therapy is one of the first-line therapies for psoriasis due to its high response rate, relative low cost, and minimal generalized immunosuppression compared to other systemic therapies. This chapter will outline the basic principles of photomedicine and photochemistry before delving into the evidence behind the use of current and emerging UV, laser, and light therapies in psoriasis. Practical considerations, such as their indications, contraindications, administration, combination therapies, relevant adverse effects, and application in special populations (pregnancy, pediatrics, and those without access to in-office treatment), will also be discussed.

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  1. Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA

    James L. Griffith, Allison J. Zarbo & Henry W. Lim

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  1. Department of Dermatology UCSF Psoriasis Center, University of California, San Francisco, California, USA

    Tina Bhutani

  2. Department of Dermatology UCSF Psoriasis Center, University of California, San Francisco, California, USA

    Wilson Liao

  3. Department of Dermatology Psoriasis and Skin Treatment Center, University of California, San Francisco, California, USA

    Mio Nakamura

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Griffith, J.L., Zarbo, A.J., Lim, H.W. (2018). Phototherapy and Photochemotherapy. In: Bhutani, T., Liao, W., Nakamura, M. (eds) Evidence-Based Psoriasis. Updates in Clinical Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-90107-7_3

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