Abstract
Poor adherence to prescribed dosing regimens is one of the greatest sources of variation in drug response, often leading to underestimates of drug efficacy and side effects, and doses set needlessly high. The use of electronic monitors provides a continuous, compiled in real time, record of patient dosing times, dates, and patterns. Knowing the when of patient dosing activity allows one to accurately gauge drug efficacy and build reliable prognostics and claims. Objective dosing history data supports faster, smarter clinical drug development and avoids wasting time and money in medical practice. Failure to monitor individual dosing patterns means discounting the impact of poor adherence—the factor that is emerging as the single greatest cause of failed drug therapy.
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Vrijens, B., Tousset, E. (2018). Electronic Monitoring of Medication Adherence: From Dose-Counting to Dose-Clocking. In: Burnier, M. (eds) Drug Adherence in Hypertension and Cardiovascular Protection. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-319-76593-8_3
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DOI: https://doi.org/10.1007/978-3-319-76593-8_3
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