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Introduction

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Anticoagulation Therapy

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Abstract

The clinical manifestations of thromboembolic disease were first described by Hippocrates (460–370 BC). In the 17th and 18th centuries, the study of human anatomy in health and disease led to greater understanding of the pathophysiology of thrombotic disease and the first treatments for it. Modern approaches to treatment of arterial and venous thromboembolism emerged in the late 19th and 20th centuries with the identification of acetylsalicylic acid, heparin, and warfarin. The last 50 years has witnessed the development of evidence-based antithrombotic therapy management and targeted therapeutics including glycoprotein IIb/IIIa inhibitors and direct oral anticoagulants directed against thrombin and factor Xa. The ever increasing number of therapeutic agents and procedures for thromboembolic disease presents a challenge for healthcare providers to stay abreast of the latest developments in antithrombotic therapy. We hope this book will be a valuable resource for practitioners caring for patients with thrombotic disease.

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Author information

Authors and Affiliations

  1. Department of Cardiology, Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Manhasset, NY, USA

    Joe F. Lau

  2. Department of Internal Medicine, Division of Cardiovascular Medicine, Frankel Cardiovascular Center at the University of Michigan, Ann Arbor, MI, USA

    Geoffrey D. Barnes

  3. Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Michael B. Streiff

Authors
  1. Joe F. Lau
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  2. Geoffrey D. Barnes
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  3. Michael B. Streiff
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Corresponding authors

Correspondence to Joe F. Lau , Geoffrey D. Barnes or Michael B. Streiff .

Editor information

Editors and Affiliations

  1. Associate Professor of Cardiology, Department of Cardiology, Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Manhasset, New York, USA

    Joe F. Lau

  2. Assistant Professor, Division of Internal Medicine, Frankel Cardiovascular Center at the University of Michigan, Ann Arbor, Michigan, USA

    Geoffrey D. Barnes

  3. Professor of Medicine and Pathology, Division of Hematology, Department of Medicine, The Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA

    Michael B. Streiff

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Lau, J.F., Barnes, G.D., Streiff, M.B. (2018). Introduction. In: Lau, J., Barnes, G., Streiff, M. (eds) Anticoagulation Therapy . Springer, Cham. https://doi.org/10.1007/978-3-319-73709-6_1

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  • DOI: https://doi.org/10.1007/978-3-319-73709-6_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-73708-9

  • Online ISBN: 978-3-319-73709-6

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