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Peptide-Based Materials for Cartilage Tissue Regeneration

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Peptides and Peptide-based Biomaterials and their Biomedical Applications

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1030))

Abstract

Cartilaginous tissue requires structural and metabolic support after traumatic or chronic injuries because of its limited capacity for regeneration. However, current techniques for cartilage regeneration are either invasive or ineffective for long-term repair. Developing alternative approaches to regenerate cartilage tissue is needed. Therefore, versatile scaffolds formed by biomaterials are promising tools for cartilage regeneration. Bioactive scaffolds further enhance the utility in a broad range of applications including the treatment of major cartilage defects. This chapter provides an overview of cartilage tissue, tissue defects, and the methods used for regeneration, with emphasis on peptide scaffold materials that can be used to supplement or replace current medical treatment options.

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Author information

Authors and Affiliations

  1. Institute of Materials Science and Nanotechnology, National Nanotechnology Research Center (UNAM), Bilkent University, Ankara, 06800, Turkey

    Nurcan Hastar, Elif Arslan, Mustafa O. Guler & Ayse B. Tekinay

  2. Institute for Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA

    Mustafa O. Guler

  3. Neuroscience Graduate Program, Bilkent University, Ankara, 06800, Turkey

    Ayse B. Tekinay

Authors
  1. Nurcan Hastar
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  2. Elif Arslan
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  3. Mustafa O. Guler
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  4. Ayse B. Tekinay
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Corresponding author

Correspondence to Ayse B. Tekinay .

Editor information

Editors and Affiliations

  1. Department of Chemistry and Biomolecular Sciences, Macquarie University, North Ryde, New South Wales, Australia

    Anwar Sunna

  2. Biomolecular Discovery and Design, Research Centre, Macquarie University, North Ryde, New South Wales, Australia

    Andrew Care

  3. Department of Chemistry and Biomolecular Sciences, Macquarie University, North Ryde, New South Wales, Australia

    Peter L. Bergquist

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Hastar, N., Arslan, E., Guler, M.O., Tekinay, A.B. (2017). Peptide-Based Materials for Cartilage Tissue Regeneration. In: Sunna, A., Care, A., Bergquist, P. (eds) Peptides and Peptide-based Biomaterials and their Biomedical Applications. Advances in Experimental Medicine and Biology, vol 1030. Springer, Cham. https://doi.org/10.1007/978-3-319-66095-0_7

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