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Non-Colorectal Liver Metastases

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Gastrointestinal Malignancies

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

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Abstract

The liver is one of the most common sites of metastasis from multiple tumor histologies. With the advent of more effective chemotherapy and imaging techniques, local treatment of isolated liver lesions in the appropriate clinical scenario has the potential to extend life and decrease morbidity from disruption of liver function. While this has primarily been studied in colorectal metastases, the same principles are now being shown to apply in multiple tumor types. While the gold standard treatment has been surgical resection, numerous interventional techniques have been developed to provide local treatment in patients who are not surgical candidates. SBRT to liver metastases of multiple histologies has been shown to provide very good local control, with longer than historical median survival, giving the radiation oncologist an important role in managing patients in this oligometastatic setting. In this chapter, we will review the various modalities used to deliver local therapy to isolated non-colorectal liver metastases and cover planning considerations for delivery of SBRT to these lesions.

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Authors and Affiliations

  1. University of Colorado Cancer Center, Aurora, CO, USA

    Adam C. Mueller M.D., Ph.D., William A. Stokes M.D., Dale Thornton R.T., C.M.D. & Tracey Schefter M.D.

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  1. Adam C. Mueller M.D., Ph.D.
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  2. William A. Stokes M.D.
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  3. Dale Thornton R.T., C.M.D.
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Editors and Affiliations

  1. Department of Radiation Oncology, Case Western Reserve University, Cleveland, Ohio, USA

    Suzanne Russo

  2. Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida, USA

    Sarah Hoffe

  3. Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington, USA

    Edward Kim

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Mueller, A.C., Stokes, W.A., Thornton, D., Schefter, T. (2018). Non-Colorectal Liver Metastases. In: Russo, S., Hoffe, S., Kim, E. (eds) Gastrointestinal Malignancies. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-64900-9_6

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  • DOI: https://doi.org/10.1007/978-3-319-64900-9_6

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