Skip to main content

A Performance Evaluation of Systematic Analysis for Combining Multi-class Models for Sickle Cell Disorder Data Sets

  • Conference paper
  • First Online:
Intelligent Computing Theories and Application (ICIC 2017)

Abstract

Machine learning approach is considered as a field of science aiming specifically to extract knowledge from the data sets. The main aim of this study is to provide a sophisticate model to difference applications of machine learning models for medically related problems. We attempt for classifying the amount of medications for each patient with Sickle Cell disorder. We present a new technique to combine two classifiers between the Levenberg-Marquartdt training algorithm and the k-nearest neighbours algorithm. In this paper, we introduce multi-class label classification problem in order to obtain training and testing methods for each models along with other performance evaluations. In machine learning, the models utilise a training sets in association with building a classifier that provide a reliable classification. This research discusses different aspects of machine learning approaches for the classification of biomedical data. We are mainly focus on the multi-class label classification problem where many number of classes are available in the data sets. Results have indicated that for the machine learning models tested, the combination classifiers were found to yield considerably better results over the range of performance measures that been selected for this research.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Weatherall, D.J.: The importance of micromapping the gene frequencies for the common inherited disorders of haemoglobin. Br. J. Haematol. 149, 635–637 (2010)

    Article  Google Scholar 

  2. Kosaryan, M., Karami, H., Zafari, M., Yaghobi, N.: Report on patients with non transfusion-dependent β-thalassemia major being treated with hydroxyurea attending the Thalassemia Research Center, Sari, Mazandaran Province, Islamic Republic of Iran in 2013. Hemoglobin 38, 115–118 (2014)

    Article  Google Scholar 

  3. Al-Jumeily, D., Hussain, A., Fergus, P.: Using adaptive neural networks to provide self-healing autonomic software. Int. J. Space Based Situated Comput. 5, 129–140 (2015)

    Article  Google Scholar 

  4. Khalaf, M., et al.: Training neural networks as experimental models: classifying biomedical datasets for sickle cell disease. In: Huang, D.-S., Bevilacqua, V., Premaratne, P. (eds.) ICIC 2016. LNCS, vol. 9771, pp. 784–795. Springer, Cham (2016). doi:10.1007/978-3-319-42291-6_78

    Chapter  Google Scholar 

  5. Al-Jumeily, D., Iram, S., Vialatte, F.-B., Fergus, P., Hussain, A.: A novel method of early diagnosis of Alzheimer’s disease based on EEG signals. Sci. World J. 2015, 11 (2015). Article ID: 931387. http://dx.doi.org/10.1155/2015/931387

  6. Khalaf, M., Hussain, A.J., Keight, R., Al-Jumeily, D., Fergus, P., Keenan, R., Tso, P.: Machine learning approaches to the application of disease modifying therapy for sickle cell using classification models. Neurocomputing 228, 154–164 (2017)

    Article  Google Scholar 

  7. Ionescu, R.T., Popescu, M.: Knowledge Transfer between Computer Vision and Text Mining. Similarity-Based Learning Approaches. ACVPR. Springer, Cham (2016). doi:10.1007/978-3-319-30367-3

    Book  Google Scholar 

  8. Marquardt, D.W.: An algorithm for least-squares estimation of nonlinear parameters. J. Soc. Ind. Appl. Math. 11, 431–441 (1963)

    Article  MathSciNet  MATH  Google Scholar 

  9. Hagan, M.T., Menhaj, M.B.: Training feedforward networks with the Marquardt algorithm. IEEE Trans. Neural Netw. 5, 989–993 (1994)

    Article  Google Scholar 

  10. Cortes, C., Vapnik, V.: Support-vector networks. Mach. Learn. 20, 273–297 (1995)

    MATH  Google Scholar 

  11. Vapnik, V.: The Nature of Statistical Learning Theory. Springer Science & Business Media, New York (2013)

    MATH  Google Scholar 

  12. Al Kafri, A.S., Sudirman, S., Hussain, A.J., Fergus, P., Al-Jumeily, D., Al-Jumaily, M., Al-Askar, H.: A framework on a computer assisted and systematic methodology for detection of chronic lower back pain using artificial intelligence and computer graphics technologies. In: Huang, D.-S., Bevilacqua, V., Premaratne, P. (eds.) ICIC 2016. LNCS, vol. 9771, pp. 843–854. Springer, Cham (2016). doi:10.1007/978-3-319-42291-6_83

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohammed Khalaf .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Khalaf, M. et al. (2017). A Performance Evaluation of Systematic Analysis for Combining Multi-class Models for Sickle Cell Disorder Data Sets. In: Huang, DS., Jo, KH., Figueroa-García, J. (eds) Intelligent Computing Theories and Application. ICIC 2017. Lecture Notes in Computer Science(), vol 10362. Springer, Cham. https://doi.org/10.1007/978-3-319-63312-1_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-63312-1_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-63311-4

  • Online ISBN: 978-3-319-63312-1

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics