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Newer and Evolving Endoscopic Therapies for Gastroesophageal Reflux Disease

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Diagnostic and Therapeutic Procedures in Gastroenterology

Part of the book series: Clinical Gastroenterology ((CG))

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Abstract

Gastroesophageal reflux disease (GERD) is the most common disorder of the esophagus and the most common reason for gastroenterology consultation. Pharmacotherapy with proton pump inhibitors and histamine receptor antagonists has revolutionized the treatment of GERD and is able to yield symptomatic relief in the majority of compliant patients. However, many patients have incomplete or unsatisfactory responses to maximal medical management due to a number of factors, including hypersensitivity, volume or bile refluxate, poor compliance, and the inability of pharmacotherapy to address the underlying anatomic and neuromuscular deficits responsible for GERD. Laparoscopic Nissen fundoplication remains the gold standard for invasive therapy for GERD. This chapter will discuss existing and evolving endoscopic treatments for GERD and the available evidence to support their use.

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Author information

Authors and Affiliations

  1. Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

    Phillip S. Ge & V. Raman Muthusamy

  2. Division of Digestive Diseases/Department of Medicine, UCLA Medical Center, 200 UCLA Medical Plaza, Suite 330-37, Los Angeles, CA, 90095, USA

    V. Raman Muthusamy

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  1. Phillip S. Ge
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  2. V. Raman Muthusamy
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Correspondence to V. Raman Muthusamy .

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Editors and Affiliations

  1. Advanced Endoscopy, Digestive Health Center, Section of Gastroenterology & Hepatology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

    Subbaramiah Sridhar

  2. Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, Connecticut, USA

    George Y. Wu

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Ge, P.S., Muthusamy, V.R. (2018). Newer and Evolving Endoscopic Therapies for Gastroesophageal Reflux Disease. In: Sridhar, S., Wu, G. (eds) Diagnostic and Therapeutic Procedures in Gastroenterology. Clinical Gastroenterology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-62993-3_4

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  • DOI: https://doi.org/10.1007/978-3-319-62993-3_4

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  • Online ISBN: 978-3-319-62993-3

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