Abstract
The events of September 11, 2001 were of a magnitude our country has never experienced. Responders of the traditional and nontraditional sense rushed in to help those trapped in the towers, often without considering their own personal safety. It was immediately apparent to the science and healthcare communities that the dust that enveloped responders and those in Lower Manhattan presented a serious health hazard. Health monitoring programs were established in a more expedient fashion than research has typically seen in the past. However, it took a number of years for funding to become available for further health research on these responders. This research has provided the scientific community with a vast knowledge of comorbidities from a variety of toxins that would otherwise be unsubstantiated.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Pleil JD, Vette AF, Johnson BA, Rappaport SM. Air levels of carcinogenic polycyclic aromatic hydrocarbons after the World Trade Center disaster. Proc Natl Acad Sci U S A. 2004;101:11685–8.
Lioy PJ, Weisel CP, Millette JR, Eisenreich S, Vallero D, Offenberg J, Buckley B, Turpin B, Zhong M, Cohen MD, Prophete C, Yang I, Stiles R, Chee G, Johnson W, Porcja R, Alimokhtari S, Hale RC, Weschler C, Chen LC. Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in lower Manhattan after the collapse of the WTC 11 September 2001. Environ Health Perspect. 2002;10:703–14.
McGee JK, Chen LC, Cohen MD, Chee GR, Prophete CM, Haykal-Coates N, Wasson SJ, Conner TL, Costa DL, Gavett SH. Chemical analysis of World Trade Center fine particulate matter for use in toxicologic assessment. Environ Health Perspect. 2003;111:972–80.
EPA, U. S. Exposure and human health evaluation of airborne pollution from the World Trade Center disaster – external review draft. Washington, DC: U.S. Environmental Protection Agency; 2002.
CDC. Occupational exposures to air contaminants at the World Trade Center disaster site – New York, September-October, 2001. MMWR Morb Mortal Wkly Rep. 2002;51:453–6.
Banauch G, Dhala A, Prezant D. Pulmonary disease in rescue workers at the World Trade Center site. Curr Opin Pulm Med. 2005;11:160–8.
EPA, U. S. Toxicological effects of fine particulate matter derived from the destruction of the World Trade Center. Research Triangle Park, NC: U.S. Environmental Protection Agency; 2002.
Jeffrey N, D’andrea C, Leighton J, Rodenbeck S, Wilder L, Devoney D, Neurath S, Lee C, Williams R. Potential exposures to airborne and settled surface dust in residential areas of lower Manhattan following the collapse of the World Trade Center – New York City, November 4–December 11, 2001. Morb Mortal Wkly Rep. 2003;52:131–6.
Offenberg JH, Eisenreich SJ, Gigliotti CL, Chen LC, Xiong JQ, Quan C, Xiaopeng L, Zhong M, Gorczynski J, Yiin L-M, Illacqua V, Lioy PJ. Persistent organic pollutants in dusts that settled indoors in lower Manhattan after September 11, 2001. J Expo Anal Environ Epidemiol. 2004;14:164–72.
Service, R. World Trade Center. Chemical studies of 9/11 disaster tell complex tale of ‘bad stuff’. Science. 2003;301:1649.
Wallingford KM, Snyder EM. Occupational exposures during the World Trade Center disaster response. Toxicol Ind Health. 2001;17:247–53.
Fireman EM, Lerman Y, Ganor E, Greif J, Fireman-Shoresh S, Lioy PJ, Banauch GI, Weiden M, Kelly KJ, Prezant DJ. Induced sputum assessment in New York City firefighters exposed to World Trade Center dust. Environ Health Perspect. 2004;112:1564–9.
Herbert R, Moline J, Skloot GS, Metzger K, Baron S, Luft B, Markowitz S, Udasin I, Harrison D, Stein D, Todd AC, Enright P, Mager Stellman J, Landrigan PJ, Levin S. The World Trade Center disaster and the health of workers: five-year assessment of a unique medical screening program. Environ Health Perspect. 2006;114:1853–8.
Levin S, Herbert R, Skloot GS, Szeinuk J, Teirstein AS, Fischler D, Milek D, Piligian G, Wilk-Rivard E, Moline J. Health effects of World Trade Center site workers. Am J Ind Med. 2002;42:545–7.
Prezant DJ, Weiden M, Banauch GI, McGuinness G, Rom WN, Aldrich TK, Kelly KJ. Cough and bronchial responsiveness in firefighters at the World Trade Center site. N Engl J Med. 2002;347:806–15.
Mann JM, Sha KK, Kline G, Breuer FU, Miller A. World Trade Center dyspnea: bronchiolitis obliterans with functional improvement: a case report. Am J Ind Med. 2005;48:225–9.
Rom WN, Weiden M, Garcia R, Yie TA, Vathesatogkit P, Tse DB, McGuinness G, Roggli V, Prezant D. Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. Am J Respir Crit Care Med. 2002;166:797–800.
Safirstein BH, Klukowicz A, Miller R, Teirstein A. Granulomatous pneumonitis following exposure to the World Trade Center collapse. Chest. 2003;123:301–4.
CDC. Physical health status of World Trade Center rescue and recovery workers and volunteers – New York City, July 2002–August 2004. MMWR Morb Mortal Wkly Rep. 2004;53:807–12.
Moline JM, Herbert R, Crowley LE, Troy K, Hodgman E, Shukla G, Udasin I, Luft BJ, Wallenstein S, Landrigan P, Savitz DA. Multiple myeloma in World Trade Center responders: a case series. J Occup Environ Med. 2009;51:896–902.
James Zadroga 9/11 Health and Compensation Act of 2010.
Lioy PJ, Gochfeld M. Lessons learned on environmental, occupational, and residential exposures from the attack on the World Trade Center. Am J Ind Med. 2002;42:560–5.
USGS. U.S. Geological Survey open file report OFR-01-0429. Environmental studies of the World Trade Center area after the September 11, 2001 attack. Reston: U.S. Geological Survey; 2002.
Lioy PJ, Weisel CP, Millette JR, Eisenreich S, Vallero D, Offenberg J, Buckley B, Turpin B, Zhong M, Cohen MD, Prophete C, Yang I, Stiles R, Chee G, Johnson W, Porcja R, Alimokhtari S, Hale RC, Weschler C, Chen LC. Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in lower Manhattan after the collapse of the WTC 11 September 2001. Environ Health Perspect. 2002;110:703–14.
Gavett SH, Haykal-Coates N, Highfill JW, Ledbetter AD, Chen LC, Cohen MD, Harkema JR, Wagner JG, Costa DL. World Trade Center fine particulate matter causes respiratory tract hyperresponsiveness in mice. Environ Health Perspect. 2003;111:981–91.
Prezant DJ. World Trade Center Cough Syndrome and its treatment. Lung. 2008;186(Suppl 1):S94–102.
Wisnivesky JP, Teitelbaum SL, Todd AC, Boffetta P, Crane M, Crowley L, De la Hoz RE, Dellenbaugh C, Harrison D, Herbert R, Kim H, Jeon Y, Kaplan J, Katz CL, Levin S, Luft B, Markowitz S, Moline J, Ozbay F, Pietrzak RH, Shapiro M, Sharma V, Skloot GS, Southwick S, Stevenson LA, Udasin I, Wallenstein S, Landrigan P. Persistence of multiple illnesses in World Trade Center rescue and recovery workers: a cohort study. Lancet. 2011;378:888–97.
Izbicki G, Chavko R, Banauch GI, Weiden MD, Berger KI, Aldrich TK, Hall C, Kelly KJ, Prezant DJ. World Trade Center “sarcoid-like” granulomatous pulmonary disease in New York City Fire Department rescue workers. Chest. 2007;131:1414–23.
Jordan HT, Stellman SD, Prezant DJ, Teirstein AS, Osahan SS, Cone JE. Sarcoidosis diagnosed after September 11, 2001 among adults exposed to the World Trade Center disaster. J Occup Environ Med. 2011;53:966–74.
Crowley LE, Herbert R, Moline JM, Wallenstein S, Shukla G, Schechter CB, Skloot GS, Udasin I, Luft BJ, Harrison D, Shapiro M, Wong K, Sacks HS, Landrigan PJ, Teirstein AS. “Sarcoid like” granulomatous pulmonary disease in World Trade Center disaster responders. Am J Ind Med. 2011;54:175–84.
Skloot GS, Schechter CB, Herbert R, Moline JM, Levin SM, Crowley LE, Luft BJ, Udasin IG, Enright PL. Longitudinal assessment of spirometry in the World Trade Center medical monitoring program. Chest. 2009;135:492–8.
Berger KI, Reibman J, Oppenheimer BW, Vlahos I, Harrison D, Goldring RM. Lessons from the World Trade Center Disaster: airway disease presenting as restrictive dysfunction. Chest. 2013;144:249–57.
Friedman SM, Maslow CB, Reibman J, Pillai PS, Goldring RM, Farfel MR, Stellman SD, Berger KI. Case-control study of lung function in World Trade Center Health Registry area residents and workers. Am J Respir Crit Care Med. 2011;184:582–9.
Banauch GI, Hall C, Weiden M, Cohen HW, Aldrich TK, Christodoulou V, Arcentales N, Kelly KJ, Prezant DJ. Pulmonary function after exposure to the World Trade Center collapse in the New York City Fire Department. Am J Respir Crit Care Med. 2006;174:312–9.
Aldrich TK, Gustave J, Hall C, Cohen HW, Webber MP, Zeig-Owens R, Cosenza K, Christodoulou V, Glass L, Al-Othman F, Weiden M, Kelly KJ, Prezant DJ. Lung function in rescue workers at the World Trade Center after 7 years. N Engl J Med. 2010;362:1263–72.
Weiden M, Ferrier N, Nolan A, Rom W, Comfort A, Gustave J, Zeig-Owens R, Zheng S, Goldring R, Berger K, Cosenza K, Lee R, Webber M, Kelly K, Aldrich T, Prezant D. Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust. Chest. 2010;137:566–74.
Banauch GI, Brantly M, Izbicki G, Hall C, Shanske A, Chauko R, Santhyadka G, Christodoulou V, Weiden MD, Prezant DJ. Accelerated spirometric decline in New York City firefighters with alpha1-antitrypsin deficiency. Chest. 2010;138:1116–24.
Salzman SH, Moosavy FM, Miskoff JA, Friedmann P, Fried G, Rosen MJ. Early respiratory abnormalities in emergency services police officers at the World Trade Center site. J Occup Environ Med. 2004;46:113–22.
Skloot G, Goldman M, Fischler D, Goldman C, Schechter C, Levin S, Teirstein A. Respiratory symptoms and physiologic assessment of ironworkers at the World Trade Center disaster site. Chest. 2004;125:1248–55.
Oppenheimer B, Goldring R, Herberg M, Hofer I, Reyfman P, Liautaud S, Rom W, Reibman J, Berger K. Distal airway function in symptomatic subjects with normal spirometry following World Trade Center dust exposure. Chest. 2007;132:1275–82.
Solan S, Wallenstein S, Shapiro M, Teitelbaum S, Stevenson L, Kochman A, Kaplan J, Dellenbaugh C, Kahn A, Biro F, Crane M, Crowley L, Gabrilove J, Gonsalves L, Harrison D, Herbert R, Luft B, Markowitz S, Moline J, Niu X, Sacks H, Shukla G, Udasin I, Lucchini R, Boffetta P, Landrigan P. Cancer incidence in World Trade Center rescue and recovery workers, 2001-2008. Environ Health Perspect. 2013;121:699–704.
Zeig-Owens R, Webber MP, Hall C, Schwartz T, Jaber N, Weakley J, Rohan TE, Cohen HW, Derman O, Aldrich TK, Kelly KJ, Prezant DJ. Early assessment of cancer outcomes in New York City firefighters after the 9/11 attacks: an observational cohort study. Lancet. 2011;378:898–905.
Department of Health and Human Services, U. S. 42 CFR part 88 – World Trade Center health program requirements for the addition of new WTC-related health conditions. Washington, D.C.: Department of Health and Human Services; 2012.
CDC 2015. WTC Health Program Research-to-Care Logic Model. 1–5. From the WTC health program steering committee; 2015.
Moline J, Herbert R, Nguyen N. Health consequences of the September 11 World Trade Center attacks: a review. Cancer Investig. 2006;24:294–301.
Nolan RP, Ross M, Nord GL, Axten CW, Osleeb JP, Domnin SG, Bertram P, Wilson R. Risk assessment for asbestos-related cancer from the 9/11 attack on the World Trade Center. J Occup Med. 2005;47:817–25.
Rayne S. Using exterior building surface films to assess human exposure and health risks from PCDD/Fs in New York City, USA, after the World Trade Center attacks. J Hazard Mater. 2005;127:33–9.
Samet JM, Geyh AS, Utell MJ. The legacy of World Trade Center dust. N Engl J Med. 2007;356:2233–6.
World Trade Center Health Program Research Projects [Online]. WTC Health Program Research Gateway. 2016. Available: https://wwwn.cdc.gov/ResearchGateway/ResearchProjects. Accessed 7 Nov 2016.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this chapter
Cite this chapter
Moline, J., Wilson, L., Smith, F.R. (2018). The Influence of the WTC Programs on Research. In: Szema, A. (eds) World Trade Center Pulmonary Diseases and Multi-Organ System Manifestations. Springer, Cham. https://doi.org/10.1007/978-3-319-59372-2_1
Download citation
DOI: https://doi.org/10.1007/978-3-319-59372-2_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-59371-5
Online ISBN: 978-3-319-59372-2
eBook Packages: MedicineMedicine (R0)