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Sialadenosis

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Gland-Preserving Salivary Surgery

Abstract

Sialadenosis (sialosis) is a chronic, noninflammatory, nonneoplastic, bilateral, often painless enlargement of the salivary glands, most frequently affecting the parotid glands. Half of all cases are associated with an underlying disease process, such as diabetes, cirrhosis, or malnutrition. The pathogenesis is unknown, but it is currently believed to be secondary to an autonomic neuropathy. To rule out the vast differential diagnosis of bilateral parotid swelling, a thorough history and physical examination, in combination with blood testing, diagnostic imaging, and in some cases biopsies, is necessary. Conservative management has been the mainstay of treatment, starting with treating the underlying medical comorbidity, but if a patient has pain or aesthetic concerns, more invasive options are available.

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Authors and Affiliations

  1. Otolaryngology Department, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA

    Andrew B. Davis M.D. & Henry T. Hoffman M.D.

Authors
  1. Andrew B. Davis M.D.
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  2. Henry T. Hoffman M.D.
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Corresponding author

Correspondence to Henry T. Hoffman M.D. .

Editor information

Editors and Affiliations

  1. Otolaryngology-Head and Neck Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA

    M. Boyd Gillespie

  2. Otolaryngology Head and Neck Surgery, Louisiana State University, New Orleans, Louisiana, USA

    Rohan R. Walvekar

  3. School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Barry M. Schaitkin

  4. Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    David W. Eisele

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Davis, A.B., Hoffman, H.T. (2018). Sialadenosis. In: Gillespie, M., Walvekar, R., Schaitkin, B., Eisele, D. (eds) Gland-Preserving Salivary Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-58335-8_13

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  • DOI: https://doi.org/10.1007/978-3-319-58335-8_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-58333-4

  • Online ISBN: 978-3-319-58335-8

  • eBook Packages: MedicineMedicine (R0)

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