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Protein Import Channels in the Crossroads of Mitochondrial Function

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Molecular Basis for Mitochondrial Signaling

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

Mitochondrial biogenesis and function, since the eukaryotic merger millions of years ago to now, relies on protein import channels across its membranes. This chapter reviews the current literature on the import pathways, how they are regulated, and how they are involved in emerging mitochondrial functions, from biogenesis to transcriptional regulation, stress response, and metabolic reprograming.

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Acknowledgments

This work was supported partially by CUNY CIRG grant 80209 and Eugene Lang Foundation grant 78592 to PMP.

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Authors and Affiliations

  1. Macaulay Honors College at Baruch College of City University of New York, New York, NY, USA

    Ma Su Su Aung

  2. Graduate Center and Baruch College of City University of New York, New York, NY, 10010, USA

    Ruth Hartke, Stephen Madamba & Pablo M. Peixoto

  3. Baruch College of City University of New York, New York, NY, USA

    Oygul Mirzalieva

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Correspondence to Pablo M. Peixoto .

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  1. Section on Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

    Tatiana K. Rostovtseva

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Aung, M.S.S., Hartke, R., Madamba, S., Mirzalieva, O., Peixoto, P.M. (2017). Protein Import Channels in the Crossroads of Mitochondrial Function. In: Rostovtseva, T. (eds) Molecular Basis for Mitochondrial Signaling. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-55539-3_12

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