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The Antiviral Activity of Probiotic Metabolites

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New Insights on Antiviral Probiotics

Abstract

One of the most important characteristics of lactic acid bacteria (LAB) is the production of a large variety of active substances, such as acids, active ribosomal proteins, non-ribosomal peptide synthetase (NRPS), hydrogen peroxide, and other metabolites. In recent decades, several studies have evaluated the importance of these active substances in both the medical and food sectors. LAB have been used for several years in food fermentation to give good taste and protect the food against spoilage and pathogenic microorganisms. In this chapter, we focus on the antiviral activity of LAB metabolites.

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Abbreviations

CA16:

Coxsackievirus A 16

CFS:

Cell-free supernatant

CRFK:

Crandell–Reese feline kidney

EMCV:

Murine encephalomyocarditis virus

FCV:

Feline calicivirus

FDA:

Food and Drug Administration

GRAS:

Generally recognized as safe

H2O2 :

Hydrogen peroxide

HSV-1:

Herpes simplex viruses 1

HSV-2:

Herpes simplex viruses 2

kDa:

Kilodalton

LAB:

Lactic acid bacteria

LabyA1:

Labyrinthopeptin A1

lcFOS:

Long-chain fructooligosaccharides

NRPs:

Non-ribosomal peptides

NRPS:

Non-ribosomal peptide synthetase

PEDV:

Porcine epidemic diarrhea virus

scGOS:

Short-chain galactooligosaccharides

SFV:

Semliki Forest virus

SHV-1:

Suid herpesvirus

SIV:

Simian immunodeficiency virus

VSV:

Vesicular stomatitis virus

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  1. Laboratoire de Microbiologie Environnement et Santé (LMSE), Doctoral School of Sciences and Technology/Faculty of Public Health Lebanese University, Tripoli, Lebanon

    Imad AL KASSAA

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AL KASSAA, I. (2017). The Antiviral Activity of Probiotic Metabolites. In: New Insights on Antiviral Probiotics. Springer, Cham. https://doi.org/10.1007/978-3-319-49688-7_4

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