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Mycobacterium scrofulaceum Infection

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Mycobacterial Skin Infections

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Abstract

Mycobacterium scrofulaceum is a member of the Runyon class II scotochromogen acid-fast bacilli [1–3]. It is widely present in nature, but is now an infrequent human pathogen. It was first described in the 1950s [4–6] and the name likely derives from its isolation from cervical lymph nodes.

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References

  1. Weitzul S, Eichhorn PJ, Pandya AG (2000) Nontuberculous mycobacterial infections of the skin. Dermatol Clin 18:359

    Article  CAS  PubMed  Google Scholar 

  2. Griffith DE, Aksamit T, Brown-Elliot BA et al (2007) An official ATS/IDSA steatment: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 175:367

    Article  CAS  PubMed  Google Scholar 

  3. Horowitz EA (2011) Mycobacterium scrofulaceum. In: Schlossberg D (ed) Tuberculosis and nontuberculous mycobacterial infections, 6th edn. ASM Press, Washington, DC, p 601

    Chapter  Google Scholar 

  4. Prissick FH, Masson AM (1952) A preliminary report on a study of pigmented mycobacteria. Can J Public Health 43:34

    Google Scholar 

  5. Prissick FH, Masson AM (1956) Cervical lymphadenitis in children caused by chromogenic mycobacteria. Can Med Assoc J 75:798

    PubMed  PubMed Central  Google Scholar 

  6. Prissick FH, Masson AM (1957) Yellow pigmented pathogenic mycobacteria from cervical lymphadenitis. Can Med Assoc J 3:91

    CAS  Google Scholar 

  7. Good RC (1979) Isolation of nontuberculous mycobacteria in the United States. J Infect Dis 142:779

    Article  Google Scholar 

  8. Rogall T, Walters T, Flohr T et al (1990) Towards the phylogeny and definition of species at the molecular level within the genus Mycobacterium. Int J Syst Bacteriol 40:323

    Article  CAS  PubMed  Google Scholar 

  9. Tortoli E (2003) Impact of genotypic studies on mycobacterial taxonomy: the new mycobacteria of the 1990’s. Clin Microbiol Rev 2:319

    Google Scholar 

  10. Swanson DS, Pan X, Musser JM (1996) Identification and subspecific differentiation of Mycobacterium scrofulaceum by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein. J Clin Microbiol 34:3151

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Turenne CY, Cook VJ, Burdz TV et al (2004) Mycobacterium parascrofulaceum sp. nov., novel slowly growing scotochromogenic clinical isolate related to Mycobacterium simiae. Int J Syst Evol Microbiol 54:1543

    Article  CAS  PubMed  Google Scholar 

  12. Chapman JS, Bernard JS, Speight M (1965) Isolation of mycobacteria from raw milk. Am Rev Respir Dis 91:351

    Article  CAS  PubMed  Google Scholar 

  13. Hosty TS, McDurmount CI (1975) Isolation of acid-fast organisms from milk and oysters. Health Lab Sci 12:16

    CAS  PubMed  Google Scholar 

  14. Goslee S, Walinsky E (1976) Water as a source of potentially pathogenic mycobacteria. Am Rev Respir Dis 113:287

    CAS  PubMed  Google Scholar 

  15. Wolinsky E (1979) State of the art: nontuberculous mycobacteria and associated diseases. Am Rev Respir Dis 110:107

    Google Scholar 

  16. Le Mense GP, Van Bakel AB, Crumbley AJ et al (1994) Mycobacterium scrofulaceum infection presenting as lung nodules in a heart transplant recipient. Chest 106:1918

    Article  Google Scholar 

  17. Sanders JW, Walsh AD, Snider RL et al (1995) Disseminated Mycobacterium scrofulaceum infection: a potentially treatable complication of AIDS. Clin Infect Dis 30:444

    Google Scholar 

  18. Hsueh PR, Hsine TR, Jam JT et al (1996) Disseminated infection due to Mycobacterium scrofulaceum in an immunocompetent host. Clin Infect Dis 22:159

    Article  CAS  PubMed  Google Scholar 

  19. Dunn BL, Hodgson DJ (1982) “Atypical” mycobacteria in milk. J Appl Bacteriol 52:373

    Article  CAS  PubMed  Google Scholar 

  20. Brooks RW, Parker BC, Gruft H et al (1984) Epidemiology of infection by nontuberculous mycobacteria. Numbers in eastern United States soil and correlation with soil characteristics. Am Rev Respir Dis 130:630

    CAS  PubMed  Google Scholar 

  21. Kirschner RA Jr, Parker BC, Falkinham JO (1992) Epidemiology of infection by nontuberculous mycobacteria. Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum in acid, brown-water swamps of the southern United States and their association with environmental variables. Am Rev Respir Dis 145:271

    Article  PubMed  Google Scholar 

  22. Good RC, Snider DE (1982) Isolation of nontuberculous mycobacteria in the United States, 1980. J Infect Dis 146:829

    Article  CAS  PubMed  Google Scholar 

  23. Corbett EL, Hay M, Churchyard GJ et al (1999) Mycobacterium kansasii and Mycobacterium scrofulaceum isolated from HIV-negative South African gold miners: incidence, clinical significance and radiology. Int J Tuberc Lung Dis 3:501

    CAS  PubMed  Google Scholar 

  24. Bruins J, Gribnau JH, Bwire R (1995) Investigation into typical and atypical tuberculin sensitivity in the Royal Netherlands Army, resulting in a more rational indication for isoniazid prophylaxis. Tuber Lung Dis 76:540

    Article  CAS  PubMed  Google Scholar 

  25. Dascalopoulos GA, Loukas S, Costantopoulos SH (1995) Wide geographic variations of sensitivity of MOTT sensitins in Greece. Eur Respir J 8:715

    CAS  PubMed  Google Scholar 

  26. Kwamanga DO, Swai OB, Agwanda R et al (1995) Effect of nontuberculous mycobacteria infection on tuberculin results among primary school children in Kenya. East Afr Med J 72:222

    CAS  PubMed  Google Scholar 

  27. Svandova E, Stastna J, Kubin M (1984) Comparative testing of skin reactions to PPD mycobacterins from Mycobacterium tuberculosis and Mycobacterium scrofulaceum in school-age children. J Hyg Epidemiol Microbiol Immunol 29:275

    CAS  PubMed  Google Scholar 

  28. Lincoln EM, Gilbert LA (1972) Disease in children due to mycobacteria other than Mycobacterium tuberculosis. Am Rev Respir Dis 105:683

    CAS  PubMed  Google Scholar 

  29. Wolinsky E, Ryncarson TK (1968) Mycobacteria in soil and their relation to disease-associated strains. Am Rev Respir Dis 97:1032

    CAS  PubMed  Google Scholar 

  30. Wolinsky E (1995) Mycobacterial lymphadenitis in children: a prospective study of 105 nontuberculous cases with long-term follow-up. Clin Infect Dis 20:954

    Article  CAS  PubMed  Google Scholar 

  31. Grzybowski S, Allen EA (1995) History and importance of scrofula. Lancet 346:1472

    Article  CAS  PubMed  Google Scholar 

  32. O’Brien RJ, Geiter LJ, Snider DE Jr (1987) The epidemiology of nontuberculous mycobacterial disease in the United States. Am Rev Respir Dis 135:1007

    PubMed  Google Scholar 

  33. Margileth AM (1983) The use of purified protein derivative mycobacterial skin test antigens in children and adolescents: purified protein derivative skin test results correlated with mycobacterial isolates. Pediatr Infect Dis 2:225

    Article  CAS  PubMed  Google Scholar 

  34. Chao SS, Loh KS, Tan KK et al (2002) Tuberculous and nontuberculous cervical lymphadenitis: a clinical review. Otolaryngol Head Neck Surg 126:176

    Article  PubMed  Google Scholar 

  35. Starke JR (2000) Management of nontuberculous mycobacterial cervical adenitis. Pediatr Infect Dis 19:67

    Google Scholar 

  36. Gorse GJ, Fairshter RD, Friedly G et al (1983) Nontuberculous mycobacterial disease. Experience in a Southern California hospital. Arch Intern Med 143:225

    Article  CAS  PubMed  Google Scholar 

  37. Murray-Leisure KA, Egan N, Weitekamp MR (1987) Skin lesions caused by Mycobacterium scrofulaceum. Arch Dermatol 123:369

    Article  CAS  PubMed  Google Scholar 

  38. Abbott MR, Smith DD (1981) Mycobacteria infections in immunosuppressed patients. Med J Aust 1:351

    CAS  PubMed  Google Scholar 

  39. Sowers WF (1972) Swimming pool granuloma due to Mycobacterium scrofulaceum. Arch Dermatol 105:760

    Article  CAS  PubMed  Google Scholar 

  40. Ishii N, Sugita Y, Sato I et al (1998) A case of mycobacterial skin disease caused by Mycobacterium peregrinum and M. scrofulaceum. Acta Derm Venereol 78:76

    Article  CAS  PubMed  Google Scholar 

  41. Kandyil R, Maloney D, Tarrand J et al (2002) Red nodule on the finger of an immunosuppressed woman. Arch Dermatol 128:689

    Google Scholar 

  42. Jang H, Jo J, Oh C et al (2005) Successful treatment of localized cutaneous infection caused by Mycobacterium scrofulaceum with clarithromycin. Pediatr Dermatol 22:476

    Article  PubMed  Google Scholar 

  43. Hautmann G, Lotti T (1995) Diseases caused by Mycobacterium scrofulaceum. Clin Dermatol 13:277

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Biomedical Science and Human Oncology, University of Bari “Aldo Moro”, Bari, Italy

    Domenico Bonamonte MD, PhD

  2. University of Bari “Aldo Moro”, Bari, Italy

    Pietro Verni MD & Gianni Angelini MD (Professor of Dermatology, Former Professor and Chairman)

Authors
  1. Domenico Bonamonte MD, PhD
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  2. Pietro Verni MD
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  3. Gianni Angelini MD
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Correspondence to Domenico Bonamonte MD, PhD .

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Editors and Affiliations

  1. University of Bari “Aldo Moro”, Department of Biomedical Science and Human Oncology, Bari, Italy

    Domenico Bonamonte

  2. University of Bari “Aldo Moro”, Dermatology, Bari, Italy

    Gianni Angelini

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Bonamonte, D., Verni, P., Angelini, G. (2017). Mycobacterium scrofulaceum Infection. In: Bonamonte, D., Angelini, G. (eds) Mycobacterial Skin Infections. Springer, Cham. https://doi.org/10.1007/978-3-319-48538-6_7

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  • DOI: https://doi.org/10.1007/978-3-319-48538-6_7

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