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Multimodality Dosimetry

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Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice

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Abstract

PDT requires a multimodality approach for dosimetry because it works based on three essential components: light, photosensitizer, and molecular oxygen. Since these components are found in variable amounts inside target cells, PDT dosimetry is rather intricate. This chapter intends to address, with little mathematical complexity, the physical and chemical quantities that are most relevant for light and photosensitizer dosimetry as well as to present basic aspects of oxygen supply to achieve successful PDT interventions.

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Author information

Authors and Affiliations

  1. Center for Lasers and Applications, Nuclear and Energy Research Institute, National Commission for Nuclear Energy, Av. Lineu Prestes 2242, Cidade Universitária, Sao Paulo, 05508-000, SP, Brazil

    Martha Simões Ribeiro

  2. Department of Microbiology, Institute for Biomedical Sciences, University of São Paulo, Av. Lineu Prestes 1347, Cidade Universitária, Sao Paulo, 05508-000, SP, Brazil

    Caetano Padial Sabino

  3. Department of Clinical Analysis, School of Pharmaceutical Sciences, University of São Paulo, Sao Paulo, Brazil

    Caetano Padial Sabino

  4. Center for Lasers and Applications, Nuclear and Energy Research Institute, National Commission for Nuclear Energy, Sao Paulo, SP, Brazil

    Caetano Padial Sabino

Authors
  1. Martha Simões Ribeiro
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  2. Caetano Padial Sabino
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Corresponding author

Correspondence to Martha Simões Ribeiro .

Editor information

Editors and Affiliations

  1. University of São Paulo, Department of Internal Medicine, School of Veterinary Medicine and Animal Science, Butantã, São Paulo, Brazil

    Fábio Parra Sellera

  2. Santos Aquarium, Veterinary Unit of Santos Aquarium, Ponta da Praia, Santos, São Paulo, Brazil

    Cristiane Lassálvia Nascimento

  3. IPEN-CNEN/SP, Center for Lasers and Applications, Cidade Universitária, São Paulo, São Paulo, Brazil

    Martha Simões Ribeiro

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© 2016 Springer International Publishing Switzerland

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Ribeiro, M.S., Sabino, C.P. (2016). Multimodality Dosimetry. In: Sellera, F., Nascimento, C., Ribeiro, M. (eds) Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-45007-0_7

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