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Modern Principles of CNS Tumor Classification

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Brain Tumors in Children

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Abstract

Childhood brain tumors remain a major clinical challenge, and one that is further complicated by the fact that histologically similar or even indistinguishable tumors can show significant molecular heterogeneity—something that is still under intense investigation. Recent advances in genome and epigenome research have revealed extensive clinically useful features of distinct molecular entities, or subgroups thereof, which will help in the classification of these tumors, as well as in treatment stratification and therapeutic target identification.

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Authors and Affiliations

  1. Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany

    Stefan M. Pfister & David T. W. Jones

  2. Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany

    Stefan M. Pfister & David T. W. Jones

  3. Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany

    Stefan M. Pfister

  4. Department of Neuropathology, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Berlin, Germany

    David Capper

  5. German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany

    David Capper

Authors
  1. Stefan M. Pfister
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  2. David Capper
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  3. David T. W. Jones
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Correspondence to Stefan M. Pfister .

Editor information

Editors and Affiliations

  1. Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA

    Amar Gajjar

  2. Children’s National Medical Center, George Washington University, Silver Spring, WA, USA

    Gregory H. Reaman

  3. Cincinnati, OH, USA

    Judy M. Racadio

  4. Medpace, Cincinnati, OH, USA

    Franklin O. Smith

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Pfister, S.M., Capper, D., Jones, D.T.W. (2018). Modern Principles of CNS Tumor Classification. In: Gajjar, A., Reaman, G., Racadio, J., Smith, F. (eds) Brain Tumors in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-43205-2_6

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  • DOI: https://doi.org/10.1007/978-3-319-43205-2_6

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