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Low-Grade Gliomas

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Brain Tumors in Children

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Abstract

Tumors of the central nervous system (CNS) are the most common solid tumors in childhood and the second most common overall malignancy in children. The majority of pediatric CNS tumors are gliomas and they are most frequently low-grade. Of the pediatric low-grade gliomas (PLGG), astrocytomas are the predominating histopathologic diagnosis, and include the more prevalent pilocytic astrocytoma and diffuse astrocytoma as well as less common tumors, such as pleomorphic xanthoastrocytoma (PXA), subependymal giant cell astrocytoma (SEGA), and pilomyxoid astrocytoma. Other PLGGs include oligodendroglioma, angiocentric glioma, astroblastoma, and mixed glioneuronal tumors, such as ganglioglioma and dysembryoplastic neuroepithelial tumor (DNT).

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Authors and Affiliations

  1. Department of Radiation Oncology, University of California, San Francisco, CA, USA

    Anna K. Paulsson & Michael A. Garcia

  2. Division of Neuropathology, Department of Pathology, University of California, San Francisco, CA, USA

    David A. Solomon

  3. Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women’s Hospital, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

    Daphne A. Haas-Kogan

Authors
  1. Anna K. Paulsson
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  2. Michael A. Garcia
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  3. David A. Solomon
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  4. Daphne A. Haas-Kogan
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Corresponding author

Correspondence to Daphne A. Haas-Kogan .

Editor information

Editors and Affiliations

  1. Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA

    Amar Gajjar

  2. Children’s National Medical Center, George Washington University, Silver Spring, WA, USA

    Gregory H. Reaman

  3. Cincinnati, OH, USA

    Judy M. Racadio

  4. Medpace, Cincinnati, OH, USA

    Franklin O. Smith

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Paulsson, A.K., Garcia, M.A., Solomon, D.A., Haas-Kogan, D.A. (2018). Low-Grade Gliomas. In: Gajjar, A., Reaman, G., Racadio, J., Smith, F. (eds) Brain Tumors in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-43205-2_10

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  • DOI: https://doi.org/10.1007/978-3-319-43205-2_10

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