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Cancer, Heart Diseases, and Common Risk Factors: Smoke

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Manual of Cardio-oncology

Abstract

Cardiovascular disease is the leading cause of death worldwide, with approximately 30 % of deaths. Several studies have demonstrated that both cardiovascular morbidity and mortality are increased by cigarette smoke exposure, and this correlation has been confirmed also for environmental tobacco exposure. Epidemiologic data show that most of the damages produced by smoke exposure reverse quickly after cessation. Thus, smoking cessation is a crucial issue of cardiovascular prevention.

Lung cancer is the leading cause of cancer morbidity and mortality worldwide, and 90 % of the annual cancer deaths worldwide are attributable to cigarette smoke, including passive smoking as a strong risk factor. Smoking is directly involved in carcinogenesis; among the over 5000 compounds identified in cigarette smoke, more than 70 substances are carcinogens. The relative risk increases with amount smoked, duration, earlier starting age, tar level, and fraction smoked and decreases with time quit. Smoking cessation improves risk and mortality from cardiovascular disease and lung cancer; therefore, it is a priority, for the public health system, to reduce smoking prevalence through effective tobacco control policies.

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Catino, A., Misino, A., Logroscino, A., Montagna, E.S., Galetta, D. (2017). Cancer, Heart Diseases, and Common Risk Factors: Smoke. In: Lestuzzi, C., Oliva, S., Ferraù, F. (eds) Manual of Cardio-oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-40236-9_2

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