Abstract
Electroencephalography (EEG) is the noninvasive recording and measuring of the electrical activity of the cerebral cortex, with surface EEG performed via electrodes placed on the scalp. The recorded voltage activity is the net difference between ionic current flows within the brain, controlled by N-methyl-D-aspartate (NMDA) glutamate receptors becoming permeable to calcium ions. An EEG recording is a summation of numerous different frequencies. The depolarization and synchronous activation of many neurons generates epileptiform activity. The spike and wave activity seen in epilepsy is likely caused by cyclic depolarization and repolarization. The inhibiting feedback of the neurons results in the ultimate cessation of the epileptiform activity. The thalamus is considered to be the main site for the origin of cortical excitability. A minimum of 6 cm2 of cortical synchronous activity is needed to create a recordable scalp potential on surface EEG.
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Rana, A.Q., Ghouse, A.T., Govindarajan, R. (2017). Basics of Electroencephalography (EEG). In: Neurophysiology in Clinical Practice. In Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-39342-1_1
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DOI: https://doi.org/10.1007/978-3-319-39342-1_1
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