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Endocytoscopy: Endoscopic Imaging Techniques and Tools

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Endoscopic Imaging Techniques and Tools

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Abstract

Endocytoscopy is an optical technology based on the principle of light-microscopy. It allows the “in vivo” observation of superficial mucosal layer during endoscopic examination. Cytological and architectural characteristics are assessed in real-time to distinguish between normal and pathological mucosa. The atypia classification in order to predict histology of early-stage neoplasms has been the main application of endocytoscopy for years. More recently, some applications for benign diseases were reported. The probe-based systems have been progressively replaced by a new generation of prototypes that integrates the endocytoscopic facilities into an all-in-one endoscope, which allows a progressive zooming from standard endoscopy to endocytoscopy view.

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Abbreviations

BE:

Barrett’s esophagus

ECA:

Endocytoscopic atypia classification

ECT:

Endocytoscopy

ESSC:

Esophageal squamous cell cancer

IOA:

Inter-observer agreement

NBI:

Narrow band imaging

NPV:

Negative predictive value

PPV:

Positive predictive value

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Authors and Affiliations

  1. Digestive Diseases Center, Showa University Koto Toyosu Hospital, Toyosu 5-1-38, Koto-Ku, Tokyo, 135-8577, Japan

    Valerio Balassone M.D. & Haruhiro Inoue M.D., Ph.D., F.A.S.G.E.

Authors
  1. Valerio Balassone M.D.
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  2. Haruhiro Inoue M.D., Ph.D., F.A.S.G.E.
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Corresponding author

Correspondence to Haruhiro Inoue M.D., Ph.D., F.A.S.G.E. .

Editor information

Editors and Affiliations

  1. Department of Medicine, University of Chicago Medicine, Chicago, Illinois, USA

    Vani J.A. Konda

  2. Biological Sciences, University of Chicago Medicine, Chicago, Illinois, USA

    Irving Waxman

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Balassone, V., Inoue, H. (2016). Endocytoscopy: Endoscopic Imaging Techniques and Tools. In: Konda, V., Waxman, I. (eds) Endoscopic Imaging Techniques and Tools. Springer, Cham. https://doi.org/10.1007/978-3-319-30053-5_8

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  • DOI: https://doi.org/10.1007/978-3-319-30053-5_8

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  • Publisher Name: Springer, Cham

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