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Anxiety Disorders and Obsessive-Compulsive Disorders (OCD)

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Handbook of Assessment and Diagnosis of Autism Spectrum Disorder

Part of the book series: Autism and Child Psychopathology Series ((ACPS))

Abstract

Anxiety is known to be a commonly, co-occurring phenomenon with autism. Also, in daily practice, these symptoms often are confused with core symptoms of autism. Accurately determining OCD and anxiety from autism has important implications for treatment. This chapter reviews current methods and procedures available to help make these distinctions.

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Notes

  1. 1.

    The Dutch version of the SCARED, the SCARED-71 (Bodden, Bögels, & Muris, 2009), is an expanded, 71-item questionnaire that assesses social, separation, and generalized anxiety, panic, specific phobia, post-traumatic stress disorder, and OCD symptoms. van Steensel, Deutschman, and Bögels (2012) reported construct validity and acceptable internal consistency for total and subscales scores (except OCD) in cognitively able youth with ASD and anxiety difficulties. Discriminant validity, however, was less than that observed for youth without ASD and a raised cut-off was needed to improve sensitivity and specificity.

References

  • Achenbach, T. M. (1991). Manual for the child behavior checklist/4–18, 1991 profile. Burlington, VT: University of Vermont.

    Google Scholar 

  • Achenbach, T. M. (1997). Manual for the young adult self-report and young adult behavior checklist. Burlington, VT: University of Vermont.

    Google Scholar 

  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.

    Book  Google Scholar 

  • Bakken, T. L., Helverschou, S. B., Eilertsen, D. E., Heggelund, T., Myrbakk, E., & Martinsen, H. (2010). Psychiatric disorders in adolescents and adults with autism and intellectual disability: A representative study in one county in Norway. Research in Developmental Disabilities, 31, 1669–1677. doi:10.1016/j.ridd.2010.04.009.

    Article  PubMed  Google Scholar 

  • Beck, A. T., & Steer, R. A. (1993). Beck anxiety inventory manual. San Antonio, TX: Psychological Corporation.

    Google Scholar 

  • Beidel, D. C., Turner, S. M., & Morris, T. L. (1995). A new inventory to assess childhood social anxiety and phobia: The Social Phobia and Anxiety Inventory for Children. Psychological Assessment, 7, 73–79. doi:10.1037/1040-3590.7.1.73.

    Article  Google Scholar 

  • Birmaher, B., Brent, D. A., Chiappetta, L., Bridge, J., Monga, S., & Baugher, M. (1999). Psychometric properties of the screen for child anxiety related emotional disorders (SCARED): A replication study. Journal of the American Academy of Child & Adolescent Psychiatry, 38, 1230–1236. doi:10.1097/00004583-199910000-00011.

    Article  Google Scholar 

  • Blakeley-Smith, A., Reaven, J., Ridge, K., & Hepburn, S. (2012). Parent-child agreement of anxiety symptoms in youth with autism spectrum disorders. Research in Autism Spectrum Disorders, 6, 707–716. doi:10.1016/j.rasd.2011.07.020.

    Article  Google Scholar 

  • Bodden, D. H., Bögels, S. M., & Muris, P. (2009). The diagnostic utility of the screen for child anxiety related emotional disorders-71 (SCARED-71). Behaviour Research and Therapy, 47, 418–425. doi:10.1016/j.brat.2009.01.015.

    Article  PubMed  Google Scholar 

  • Boulter, C., Freeston, M., South, M., & Rodgers, J. (2014). Intolerance of uncertainty as a framework for understanding anxiety in children and adolescents with autism spectrum disorders. Journal of Autism and Developmental Disorders, 44, 1391–1402. doi:10.1007/s10803-013-2001-x.

    Article  PubMed  Google Scholar 

  • Bradley, E. A., Summers, J. A., Wood, H. L., & Bryson, S. E. (2004). Comparing rates of psychiatric and behavior disorders in adolescents and young adults with severe intellectual disability with and without autism. Journal of Autism and Developmental Disorders, 34, 151–161. doi:10.1023/B:JADD.0000022606.97580.19.

    Article  PubMed  Google Scholar 

  • Brereton, A. V., Tonge, B. J., & Einfeld, S. L. (2006). Psychopathology in children and adolescents with autism compared to young people with intellectual disability. Journal of Autism and Developmental Disorders, 36, 863–870. doi:10.1007/s10803-006-0125-y.

    Article  PubMed  Google Scholar 

  • Brown, T. A., DiNardo, P. A., & Barlow, D. H. (1994). Anxiety disorders interview schedule for DSM-IV (ADIS-IV). New York, NY: Oxford University Press.

    Google Scholar 

  • Buck, T. R., Viskochil, J., Farley, M., Coon, H., McMahon, W. M., Morgan, J., & Bilder, D. A. (2014). Psychiatric comorbidity and medication use in adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44, 3063–3071. doi:10.1007/s10803-014-2170-2

    Google Scholar 

  • Burnette, C. P., Mundy, P. C., Meyer, J. A., Sutton, S. K., Vaughan, A. E., & Charak, D. (2005). Weak central coherence and its relations to theory of mind and anxiety in autism. Journal of Autism and Developmental Disorders, 35, 63–73. doi:10.1007/s10803-004-1035-5.

    Article  PubMed  Google Scholar 

  • Cath, D. C., Ran, N., Smit, J. H., van Balkom, A. J., & Comijs, H. C. (2008). Symptom overlap between autism spectrum disorder, generalized social anxiety disorder and obsessive-compulsive disorder in adults: A preliminary case-controlled study. Psychopathology, 41, 101–110. doi:10.1159/000111555.

    Article  PubMed  Google Scholar 

  • Chalfant, A. M., Rapee, R., & Carroll, L. (2007). Treating anxiety disorders in children with high functioning autism spectrum disorders: A controlled trial. Journal of Autism and Developmental Disorders, 37, 1842–1857. doi:10.1007/s10803-006-0318-4.

    Article  PubMed  Google Scholar 

  • Chorpita, B. F., Yim, L., Moffitt, C., Umemoto, L. A., & Francis, S. E. (2000). Assessment of symptoms of DSM-IV anxiety and depression in children: A revised child anxiety and depression scale. Behaviour Research and Therapy, 38, 835–855. doi:10.1016/S0005-7967(99)00130-8.

    Article  PubMed  Google Scholar 

  • Costello, E. J., Egger, H. L., & Angold, A. (2005). The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity. Child and Adolescent Psychiatric Clinics of North America, 14, 631–648. doi:10.1016/j.chc.2005.06.003.

    Article  PubMed  Google Scholar 

  • Dadds, M. R., Rapee, R. M., & Barrett, P. M. (1994). Behavioral observation. In T. H. Ollendick, N. J. King, & W. Yule (Eds.), International handbook of phobic and anxiety disorders in children and adolescents (pp. 349–364). New York, NY: Plenum Press.

    Chapter  Google Scholar 

  • Davis, T. E., III, Fodstad, J. C., Jenkins, W. S., Hess, J. A., Moree, B. N., Dempsey, T., & Matson, J. L. (2010). Anxiety and avoidance in infants and toddlers with autism spectrum disorders: Evidence for differing symptom severity and presentation. Research in Autism Spectrum Disorders, 4, 305–313. doi:10.1016/j.rasd.2009.10.002

    Google Scholar 

  • Davis, T. E., III, & Ollendick, T. H. (2014). Fear: Autism spectrum disorder and/or specific phobia. In T. E. Davis III, S. W. White, & T. H. Ollendick (Eds.), Handbook of autism and anxiety (pp. 137–152). New York, NY: Springer.

    Chapter  Google Scholar 

  • Drahota, A., Wood, J. J., Sze, K. M., & van Dyke, M. (2011). Effects of cognitive behavioral therapy on daily living skills in children with high-functioning autism and concurrent anxiety disorders. Journal of Autism and Developmental Disorders, 41, 257–265. doi:10.1007/s10803-010-1037-4.

    Article  PubMed  Google Scholar 

  • Dziobek, I., Gold, S. M., Wolf, O. T., & Convit, A. (2007). Hypercholesterolemia in Asperger syndrome: Independence from lifestyle, obsessive-compulsive behavior, and social anxiety. Psychiatry Research, 149, 321–324. doi:10.1016/j.psychres.2006.02.003.

    Article  PubMed  Google Scholar 

  • Einfeld, S. L., & Tonge, B. J. (1995). The Developmental Behavior Checklist: The development and validation of an instrument to assess behavioral and emotional disturbance in children and adolescents with mental retardation. Journal of Autism and Developmental Disorders, 25, 81–104. doi:10.1007/BF02178498.

    Article  PubMed  Google Scholar 

  • Embregts, P. J. (2000). Reliability of the Child Behavior Checklist for the assessment of behavioral problems of children and youth with mild mental retardation. Research in Developmental Disabilities, 21, 31–41. doi:10.1016/S0891-4222(99)00028-1.

    Article  PubMed  Google Scholar 

  • Esbensen, A. J., Rojahn, J., Aman, M. G., & Ruedrich, S. (2003). Reliability and validity of an assessment instrument for anxiety, depression, and mood among individuals with mental retardation. Journal of Autism and Developmental Disorders, 33, 617–629. doi:10.1023/B:JADD.0000005999.27178.55.

    Article  PubMed  Google Scholar 

  • Farrugia, S., & Hudson, J. (2006). Anxiety in adolescents with Asperger syndrome: Negative thoughts, behavioral problems, and life interference. Focus on Autism and Other Developmental Disabilities, 21, 25–35. doi:10.1177/10883576060210010401.

    Article  Google Scholar 

  • Foa, E. B., & Kozak, M. J. (1986). Emotional processing of fear: Exposure to corrective information. Psychological Bulletin, 99, 20–35. doi:10.1037/0033-2909.99.1.20.

    Article  PubMed  Google Scholar 

  • Gadow, K. D., Roohi, J., DeVincent, C. J., Kirsch, S., & Hatchwell, E. (2010). Brief report: Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 40, 1139–1145. doi:10.1007/s10803-010-0961-7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Gadow, K. D., & Sprafkin, J. (1997). Early childhood inventory-4 norms manual. Stony Brook, NY: Checkmate Plus.

    Google Scholar 

  • Gadow, K. D., & Sprafkin, J. (2002). Child symptom inventory-4: Screening and norms manual. Stony Brook, NY: Checkmate Plus.

    Google Scholar 

  • Gillott, A., Furniss, F., & Walter, A. (2001). Anxiety in high-functioning children with autism. Autism, 5, 277–286. doi:10.1177/1362361301005003005.

    Article  PubMed  Google Scholar 

  • Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., … Charney, D. S. (1989). The Yale-Brown Obsessive Compulsive Scale: I. Development, use, and reliability. Archives of General Psychiatry, 46, 1006–1011. doi:10.1001/archpsyc.1989.01810110048007

    Google Scholar 

  • Gotham, K., Bishop, S. L., Hus, V., Huerta, M., Lund, S., Buja, A., … Lord, C. (2013). Exploring the relationship between anxiety and insistence on sameness in autism spectrum disorders. Autism Research, 6, 33–41. doi:10.1002/aur.1263

    Google Scholar 

  • Gotham, K., Unruh, K., & Lord, C. (2014). Depression and its measurement in verbal adolescents and adults with autism spectrum disorder. Autism. Advance online publication. doi:10.1177/1362361314536625

    Google Scholar 

  • Grondhuis, S. N., & Aman, M. G. (2012). Assessment of anxiety in children and adolescents with autism spectrum disorders. Research in Autism Spectrum Disorders, 6, 1345–1365. doi:10.1016/j.rasd.2012.04.006.

    Article  Google Scholar 

  • Guttmann-Steinmetz, S., Gadow, K. D., DeVincent, C. J., & Crowell, J. (2010). Anxiety symptoms in boys with autism spectrum disorder, attention-deficit hyperactivity disorder, or chronic multiple tic disorder and community controls. Journal of Autism and Developmental Disorders, 40, 1006–1016. doi:10.1007/s10803-010-0950-x.

    Article  PubMed  Google Scholar 

  • Hagopian, L. P., & Jennett, H. K. (2008). Behavioral assessment and treatment of anxiety in individuals with intellectual disabilities and autism. Journal of Developmental and Physical Disabilities, 20, 467–483. doi:10.1007/s10882-008-9114-8.

    Article  Google Scholar 

  • Hagopian, L., & Jennett, H. (2014). Behavioral assessment and treatment for anxiety for those with autism spectrum disorder. In T. E. Davis III, S. W. White, & T. H. Ollendick (Eds.), Handbook of autism and anxiety (pp. 155–169). New York, NY: Springer.

    Chapter  Google Scholar 

  • Hallett, V., Lecavalier, L., Sukhodolsky, D. G., Cipriano, N., Aman, M. G., McCracken, J. T., … Scahill, L. (2013). Exploring the manifestations of anxiety in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43, 2341–2352. doi:10.1007/s10803-013-1775-1

    Google Scholar 

  • Hallett, V., Ronald, A., Colvert, E., Ames, C., Woodhouse, E., Lietz, S., … Happé, F. (2013). Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls. Journal of Child Psychology and Psychiatry, 54, 1176–1185. doi:10.1111/jcpp.12068

    Google Scholar 

  • Heimberg, R. G., Hofmann, S. G., Liebowitz, M. R., Schneier, F. R., Smits, J. A. J., Stein, M. B., … Craske, M. G. (2014). Social anxiety disorder in DSM-5. Depression and Anxiety, 31, 472–479. doi:10.1002/da.22231

    Google Scholar 

  • Heimberg, R. G., Horner, K. J., Juster, H. R., Safren, S. A., Brown, E. J., Schneier, F. R., & Liebowitz, M. R. (1999). Psychometric properties of the Liebowitz Social Anxiety Scale. Psychological Medicine, 29, 199–212. doi:10.1017/s0033291798007879

    Google Scholar 

  • Helverschou, S. B., Bakken, T. L., & Martinsen, H. (2009). The psychopathology in autism checklist (PAC): A pilot study. Research in Autism Spectrum Disorders, 3, 179–195. doi:10.1016/j.rasd.2008.05.004.

    Article  Google Scholar 

  • Helverschou, S. B., & Martinsen, H. (2011). Anxiety in people diagnosed with autism and intellectual disability: Recognition and phenomenology. Research in Autism Spectrum Disorders, 5, 377–387. doi:10.1016/j.rasd.2010.05.003.

    Article  Google Scholar 

  • Hofvander, B., Delorme, R., Chaste, P., Nydén, A., Wentz, E., Ståhlberg, O., … Leboyer, M. (2009). Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry, 9(35), 1–9. doi:10.1186/1471-244X-9-35

    Google Scholar 

  • Holtmann, M., Bölte, S., & Poustka, F. (2007). Attention deficit hyperactivity disorder symptoms in pervasive developmental disorders: Association with autistic behavior domains and coexisting psychopathology. Psychopathology, 40, 172–177. doi:10.1159/000100007.

    Article  PubMed  Google Scholar 

  • Hurtig, T., Kuusikko, S., Mattila, M.-L., Haapsamo, H., Ebeling, H., Jussila, K., … Moilanen, I. (2009). Multi-informant reports of psychiatric symptoms among high-functioning adolescents with Asperger syndrome or autism. Autism, 13, 583–598. doi:10.1177/1362361309335719

    Google Scholar 

  • Jennett, H., Vasa, R. A., & Hagopian, L. (2013). Anxiety in children with autism spectrum disorder. In R. A. Vasa & A. K. Roy (Eds.), Pediatric anxiety disorders: A clinical guide (pp. 345–377). New York, NY: Springer.

    Chapter  Google Scholar 

  • Joshi, G., Petty, C., Wozniak, J., Henin, A., Fried, R., Galdo, M., … Biederman, J. (2010). The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: A large comparative study of a psychiatrically referred population. Journal of Autism and Developmental Disorders, 40, 1361–1370. doi:10.1007/s10803-010-0996-9

    Google Scholar 

  • Joshi, G., Wozniak, J., Petty, C., Martelon, M. K., Fried, R., Bolfek, A., … Biederman, J. (2013). Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: A comparative study. Journal of Autism and Developmental Disorders, 43, 1314–1325. doi:10.1007/s10803-012-1679-5

    Google Scholar 

  • Kanai, C., Iwanami, A., Hashimoto, R., Ota, H., Tani, M., Yamada, T., & Kato, N. (2011). Clinical characterization of adults with Asperger’s syndrome assessed by self-report questionnaires based on depression, anxiety, and personality. Research in Autism Spectrum Disorders, 5, 1451–1458. doi:10.1016/j.rasd.2011.02.005

    Google Scholar 

  • Keehn, R. H. M., Lincoln, A. J., Brown, M. Z., & Chavira, D. A. (2013). The Coping Cat program for children with anxiety and autism spectrum disorder: A pilot randomized controlled trial. Journal of Autism and Developmental Disorders, 43, 57–67. doi:10.1007/s10803-012-1541-9.

    Article  Google Scholar 

  • Kerns, C. M., & Kendall, P. C. (2012). The presentation and classification of anxiety in autism spectrum disorder. Clinical Psychology: Science and Practice, 19, 323–347. doi:10.1111/cpsp.12009.

    Article  Google Scholar 

  • Kerns, C. M., & Kendall, P. C. (2014). Autism and anxiety: Overlap, similarities, and differences. In T. E. Davis III, S. W. White, & T. H. Ollendick (Eds.), Handbook of autism and anxiety (pp. 75–89). New York, NY: Springer.

    Chapter  Google Scholar 

  • Kerns, C. M., Kendall, P. C., Berry, L., Souders, M. C., Franklin, M. E., Schultz, R. T., … Herrington, J. (2014). Traditional and atypical presentations of anxiety in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44, 2851–2861. doi:10.1007/s10803-014-2141-7

    Google Scholar 

  • Kerns, C. M., Kendall, P. C., Zickgraf, H., Franklin, M. E., Miller, J., & Herrington, J. (2015). Not to be overshadowed or overlooked: Functional impairments associated with comorbid anxiety disorders in youth with ASD. Behavior Therapy, 46, 29–39. doi:10.1016/j.beth.2014.03.005.

    Article  PubMed  Google Scholar 

  • Kerns, C. M., Maddox, B. B., Berry, L., Rump, K., Kendall, P. C., Schultz, R. T., … Miller, J. (2015). Brief measures of anxiety in non-treatment seeking youth with autism spectrum disorder. Autism, 19(8), 969–979.

    Google Scholar 

  • Kessler, R. C., Petukhova, M., Sampson, N. A., Zaslavsky, A. M., & Wittchen, H.-U. (2012). Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States. International Journal of Methods in Psychiatric Research, 21, 169–184. doi:10.1002/mpr.1359.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kreiser, N. L., & White, S. W. (2014). Assessment of social anxiety in children and adolescents with autism spectrum disorder. Clinical Psychology: Science and Practice, 21, 18–31. doi:10.1111/cpsp.12057.

    Article  Google Scholar 

  • Kuusikko, S., Pollock-Wurman, R., Jussila, K., Carter, A. S., Mattila, M., Ebeling, H., … Moilanen, I. (2008). Social anxiety in high-functioning children and adolescents with autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 38, 1697–1709. doi:10.1007/s10803-008-0555-9

    Google Scholar 

  • La Greca, A. M., & Stone, W. L. (1993). Social anxiety scale for children-revised: Factor structure and concurrent validity. Journal of Clinical Child Psychology, 22, 17–27. doi:10.1207/s15374424jccp2201_2.

    Article  Google Scholar 

  • Lai, M. C., Lombardo, M. V., Pasco, G., Ruigrok, A. N., Wheelwright, S. J., Sadek, S. A., … Baron-Cohen, S. (2011). A behavioral comparison of male and female adults with high functioning autism spectrum conditions. PLoS One, 6, e20835. doi:10.1371/journal.pone.0020835

    Google Scholar 

  • Lang, P. (1968). Fear reduction and fear behavior: Problems in treating a construct. In J. M. Schlien (Ed.), Research in psychotherapy (Vol. 3, pp. 90–102). Washington, DC: American Psychological Association.

    Chapter  Google Scholar 

  • Lecavalier, L., Wood, J. J., Halladay, A. K., Jones, N. E., Aman, M. G., Cook, E. H., … Hallett, V. (2014). Measuring anxiety as a treatment endpoint in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44, 1128–1143. doi:10.1007/s10803-013-1974-9

    Google Scholar 

  • Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., … Lainhart, J. E. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849–861. doi:10.1007/s10803-006-0123-0

    Google Scholar 

  • Lindsay, W. R., & Skene, D. D. (2007). The Beck Depression Inventory II and the Beck Anxiety Inventory in people with intellectual disabilities: Factor analyses and group data. Journal of Applied Research in Intellectual Disabilities, 20, 401–408. doi:10.1111/j.1468-3148.2007.00380.x.

    Article  Google Scholar 

  • MacNeil, B. M., Lopes, V. A., & Minnes, P. M. (2009). Anxiety in children and adolescents with autism spectrum disorders. Research in Autism Spectrum Disorders, 3, 1–21. doi:10.1016/j.rasd.2008.06.001.

    Article  Google Scholar 

  • Maddox, B. B., & White, S. W. (2014, May). Co-occurring social anxiety disorder in adults with autism spectrum disorder. Poster presented at the International Meeting for Autism Research, Atlanta, GA.

    Google Scholar 

  • March, J. S. (1998). Multidimensional Anxiety Scale for Children manual. North Tonawanda, NY: Multi-Health Systems.

    Google Scholar 

  • Mason, J., & Scior, K. (2004). ‘Diagnostic overshadowing’ amongst clinicians working with people with intellectual disabilities in the UK. Journal of Applied Research in Intellectual Disabilities, 17, 85–90. doi:10.1111/j.1360-2322.2004.00184.x.

    Article  Google Scholar 

  • Matson, J. L. (1995). The diagnostic assessment for the severely handicapped-revised (DASH-II). Baton Rouge, LA: Disability Consultants, LLC.

    Google Scholar 

  • Matson, J. L., & Boisjoli, J. A. (2008). Autism spectrum disorders in adults with intellectual disability and comorbid psychopathology: Scale development and reliability of the ASD-CA. Research in Autism Spectrum Disorders, 2, 276–287. doi:10.1016/j.rasd.2007.07.002.

    Article  Google Scholar 

  • Matson, J. L., Fodstad, J. C., & Mahan, S. (2009). Cutoffs, norms, and patterns of comorbid difficulties in children with developmental disabilities on the Baby and Infant Screen for Children with aUtIsm Traits (BISCUIT-Part 2). Research in Developmental Disabilities, 30, 1221–1228. doi:10.1016/j.ridd.2009.04.004.

    Article  PubMed  Google Scholar 

  • Matson, J. L., LoVullo, S. V., Rivet, T. T., & Boisjoli, J. A. (2009). Validity of the autism spectrum disorder-comorbid for children (ASD-CC). Research in Autism Spectrum Disorders, 3, 345–357. doi:10.1016/j.rasd.2008.08.002.

    Article  Google Scholar 

  • Matson, J. L., & Nebel-Schwalm, M. S. (2007). Comorbid psychopathology with autism spectrum disorder in children: An overview. Research in Developmental Disabilities, 28, 341–352. doi:10.1016/j.ridd.2005.12.004.

    Article  PubMed  Google Scholar 

  • Mayes, S. D., Calhoun, S. L., Aggarwal, R., Baker, C., Mathapati, S., Molitoris, S., & Mayes, R. D. (2013). Unusual fears in children with autism. Research in Autism Spectrum Disorders, 7, 151–158. doi:10.1016/j.rasd.2012.08.002

    Google Scholar 

  • Mayes, S. D., Calhoun, S. L., Murray, M. J., & Zahid, J. (2011). Variables associated with anxiety and depression in children with autism. Journal of Developmental and Physical Disabilities, 23, 325–337. doi:10.1007/s10882-011-9231-7.

    Article  Google Scholar 

  • Mazefsky, C., Kao, J., & Oswald, D. (2011). Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders. Research in Autism Spectrum Disorders, 5, 164–174. doi:10.1016/j.rasd.2010.03.006.

    Article  PubMed  PubMed Central  Google Scholar 

  • Mazefsky, C. A., Pelphrey, K. A., & Dahl, R. E. (2012). The need for a broader approach to emotion regulation research in autism. Child Development Perspectives, 6, 92–97. doi:10.1111/j.1750-8606.2011.00229.x.

    Article  PubMed  PubMed Central  Google Scholar 

  • McDougle, C. J., Scahill, L., Aman, M. G., McCracken, J. T., Tierney, E., Davies, M., … Vitiello, B. (2005). Risperidone for the core symptom domains of autism: Results from the study by the autism network of the research units on pediatric psychopharmacology. American Journal of Psychiatry, 162, 1142–1148. doi:10.1176/appi.ajp.162.6.1142

    Google Scholar 

  • Moseley, D. S., Tonge, B. J., Brereton, A. V., & Einfeld, S. L. (2011). Psychiatric comorbidity in adolescents and young adults with autism. Journal of Mental Health Research in Intellectual Disabilities, 4, 229–243. doi:10.1080/19315864.2011.595535.

    Article  Google Scholar 

  • Müller, E., Schuler, A., & Yates, G. B. (2008). Social challenges and supports from the perspective of individuals with Asperger syndrome and other autism spectrum disabilities. Autism, 12, 173–190. doi:10.1177/1362361307086664.

    Article  PubMed  Google Scholar 

  • Ozsivadjian, A., Hibberd, C., & Hollocks, M. J. (2014). Brief report: The use of self-report measures in young people with autism spectrum disorder to access symptoms of anxiety, depression and negative thoughts. Journal of Autism and Developmental Disorders, 44, 969–974. doi:10.1007/s10803-013-1937-1.

    Article  PubMed  Google Scholar 

  • Ozsivadjian, A., Knott, F., & Magiati, I. (2012). Parent and child perspectives on the nature of anxiety in children and young people with autism spectrum disorders: A focus group study. Autism, 16, 107–121. doi:10.1177/1362361311431703.

    Article  PubMed  Google Scholar 

  • Pandolfi, V., Magyar, C. I., & Dill, C. A. (2009). Confirmatory factor analysis of the child behavior checklist 1.5–5 in a sample of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 986–995. doi:10.1007/s10803-009-0716-5.

    Article  PubMed  PubMed Central  Google Scholar 

  • Reaven, J. A. (2009). Children with high-functioning autism spectrum disorders and co-occurring anxiety symptoms: Implications for assessment and treatment. Journal for Specialists in Pediatric Nursing, 14, 192–199. doi:10.1111/j.1744-6155.2009.00197.x.

    Article  PubMed  Google Scholar 

  • Reaven, J., Blakeley-Smith, A., Culhane-Shelburne, K., & Hepburn, S. (2012). Group cognitive behavior therapy for children with high‐functioning autism spectrum disorders and anxiety: A randomized trial. Journal of Child Psychology and Psychiatry, 53, 410–419. doi:10.1111/j.1469-7610.2011.02486.x.

    Article  PubMed  Google Scholar 

  • Reaven, J. A., Blakeley-Smith, A., Nichols, S., Dasari, M., Flanigan, E., & Hepburn, S. (2009). Cognitive-behavioral group treatment for anxiety symptoms in children with high-functioning autism spectrum disorders: A pilot study. Focus on Autism and Other Developmental Disabilities, 24, 27–37. doi:10.1177/1088357608327666.

    Article  Google Scholar 

  • Regier, D., Narrow, W., Kuhl, E., & Kupfer, D. (2009). The conceptual development of DSM-V. American Journal of Psychiatry, 166, 645–650. doi:10.1176/appi.ajp.2009.09020279.

    Article  PubMed  Google Scholar 

  • Renno, P., & Wood, J. J. (2013). Discriminant and convergent validity of the anxiety construct in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43, 2135–2146. doi:10.1007/s10803-013-1767-1.

    Article  PubMed  PubMed Central  Google Scholar 

  • Research Units on Pediatric Psychopharmacology (RUPP) Anxiety Study Group. (2002). The pediatric anxiety rating scale (PARS): Development and psychometric properties. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 1061–1069. doi:10.1097/00004583-200209000-00006.

    Article  Google Scholar 

  • Reynolds, C. R., & Kamphaus, R. W. (2004). Behavior assessment for children (2nd ed.). Circle Pines, MN: AGS.

    Google Scholar 

  • Reynolds, C. R., & Richmond, B. (1985). Revised children’s manifest anxiety scale. Los Angeles, CA: Western Psychological Services.

    Google Scholar 

  • Rieske, R. D., Matson, J. L., Davis, T. E., III, Konst, M. J., Williams, L. W., & Whiting, S. E. (2013). Examination and validation of a measure of anxiety specific to children with autism spectrum disorders. Developmental Neurorehabilitation, 16, 9–16. doi:10.3109/17518423.2012.705909.

    Article  PubMed  Google Scholar 

  • Rodgers, J., Riby, D. M., Janes, E., Connolly, B., & McConachie, H. (2012). Anxiety and repetitive behaviours in autism spectrum disorders and Williams syndrome: A cross-syndrome comparison. Journal of Autism and Developmental Disorders, 42, 175–180. doi:10.1007/s10803-011-1225-x.

    Article  PubMed  Google Scholar 

  • Ronan, K. R., Kendall, P. C., & Rowe, M. (1994). Negative affectivity in children: Development and validation of a self-statement questionnaire. Cognitive Therapy and Research, 18, 509–528. doi:10.1007/BF02355666.

    Article  Google Scholar 

  • Roohi, J., DeVincent, C. J., Hatchwell, E., & Gadow, K. D. (2009). Association of a monoamine oxidase-a gene promoter polymorphism with ADHD and anxiety in boys with autism spectrum disorder. Journal of Autism and Developmental Disorders, 39, 67–74. doi:10.1007/s10803-008-0600-8.

    Article  PubMed  Google Scholar 

  • Russell, A. J., Mataix-Cols, D., Anson, M., & Murphy, D. G. (2005). Obsessions and compulsions in Asperger syndrome and high-functioning autism. The British Journal of Psychiatry, 186, 525–528. doi:10.1192/bjp.186.6.525.

    Article  PubMed  Google Scholar 

  • Russell, A. J., Mataix-Cols, D., Anson, M. A. W., & Murphy, D. G. M. (2008). Psychological treatment for obsessive-compulsive disorder in people with autism spectrum disorders—A pilot study. Psychotherapy and Psychosomatics, 78, 59–61. doi:10.1159/000172622.

    Article  PubMed  Google Scholar 

  • Russell, E., & Sofronoff, K. (2005). Anxiety and social worries in children with Asperger syndrome. Australian and New Zealand Journal of Psychiatry, 39, 633–638. doi:10.1111/j.1440-1614.2005.01637.x.

    Article  PubMed  Google Scholar 

  • Scahill, L., McDougle, C. J., Williams, S. K., Dimitropoulos, A., Aman, M. G., McCracken, J. T., … Vitiello, B. (2006). Children’s Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 45, 1114–1123. doi:10.1097/01.chi.0000220854.79144.e7

  • Scahill, L., Riddle, M. A., McSwiggin-Hardin, M., Ort, S. I., King, R. A., Goodman, W. K., … Leckman, J. F. (1997). Children’s Yale-Brown obsessive compulsive scale: Reliability and validity. Journal of the American Academy of Child & Adolescent Psychiatry, 36, 844–852. doi:10.1097/00004583-199706000-00023

  • Schniering, C. A., & Rapee, R. M. (2002). Development and validation of a measure of children’s automatic thoughts: The children’s automatic thoughts scale. Behaviour Research and Therapy, 40, 1091–1109. doi:10.1016/S0005-7967(02)00022-0.

    Article  PubMed  Google Scholar 

  • Silverman, W. K., & Albano, A. M. (1996). Anxiety disorders interview schedule for DSM-IV: Child and parent interview schedule. London, UK: Oxford University Press.

    Google Scholar 

  • Sofronoff, K., Attwood, T., & Hinton, S. (2005). A randomised controlled trial of a CBT intervention for anxiety in children with Asperger syndrome. Journal of Child Psychology and Psychiatry, 46, 1152–1160. doi:10.1111/j.1469-7610.2005.00411.x.

    Article  PubMed  Google Scholar 

  • Spence, S. H. (1995). Social skills training: Enhancing social competence with children and adolescents. London, UK: NFER Nelson Publishing Company.

    Google Scholar 

  • Spence, S. H. (1998). A measure of anxiety symptoms among children. Behaviour Research and Therapy, 36, 545–566. doi:10.1016/S0005-7967(98)00034-5.

    Article  PubMed  Google Scholar 

  • Stern, J. A., Gadgil, M. S., Blakeley-Smith, A., Reaven, J. A., & Hepburn, S. L. (2014). Psychometric properties of the SCARED in youth with autism spectrum disorder. Research in Autism Spectrum Disorders, 8, 1225–1234. doi:10.1016/j.rasd.2014.06.008.

    Article  PubMed  PubMed Central  Google Scholar 

  • Stoddart, K. P., Burke, L., & King, R. (2012). Asperger syndrome in adulthood: A comprehensive guide for clinicians. New York, NY: W. W. North & Company.

    Google Scholar 

  • Storch, E. A., Arnold, E. B., Lewin, A. B., Nadeau, J. M., Jones, A. M., De Nadai, A. S., … Murphy, T. K. (2013). The effect of cognitive-behavioral therapy versus treatment as usual for anxiety in children with autism spectrum disorders: A randomized, controlled trial. Journal of the American Academy of Child & Adolescent Psychiatry, 52, 132–142. doi:10.1016/j.jaac.2012.11.007

    Google Scholar 

  • Storch, E. A., Ehrenreich-May, J., Wood, J. J., Jones, A. M., De Nadai, A. S., Lewin, A. B., … Murphy, T. K. (2012). Multiple informant agreement on the anxiety disorders interview schedule in youth with autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology, 22, 292–299. doi:10.1089/cap.2011.0114

    Google Scholar 

  • Storch, E. A., Wood, J. J., Ehrenreich-May, J., Jones, A. M., Park, J. M., Lewin, A. B., & Murphy, T. K. (2012). Convergent and discriminant validity and reliability of the pediatric anxiety rating scale in youth with autism spectrum disorders. Journal of Autism and Developmental Disorders, 42, 2374–2382. doi:10.1007/s10803-012-1489-9

    Google Scholar 

  • Sukhodolsky, D. G., Scahill, L., Gadow, K. D., Arnold, L. E., Aman, M. G., McDougle, C. J., … Vitiello, B. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36, 117–128. doi:10.1007/s10802-007-9165-9

    Google Scholar 

  • Tyson, K. E., & Cruess, D. G. (2012). Differentiating high-functioning autism and social phobia. Journal of Autism and Developmental Disabilities, 42, 1477–1490. doi:10.1016/j.rasd.2011.01.023.

    Article  Google Scholar 

  • Ung, D., Arnold, E. B., De Nadai, A. S., Lewin, A. B., Phares, V., Murphy, T. K., & Storch, E. A. (2014). Inter-rater reliability of the Anxiety Disorders Interview Schedule for DSM-IV in high-functioning youth with autism spectrum disorder. Journal of Developmental and Physical Disabilities, 26, 53–65. doi:10.1007/s10882-013-9343-3

    Google Scholar 

  • van Steensel, F. J. A., Bögels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical Child and Family Psychology Review, 14, 302–317. doi:10.1007/s10567-011-0097-0.

    Article  PubMed  PubMed Central  Google Scholar 

  • van Steensel, F. J., Deutschman, A. A., & Bögels, S. M. (2012). Examining the screen for child anxiety-related emotional disorder-71 as an assessment tool for anxiety in children with high-functioning autism spectrum disorders. Autism, 17, 681–692. doi:10.1177/1362361312455875.

    Article  PubMed  Google Scholar 

  • Weeks, J. W., Heimberg, R. G., Rodebaugh, T. L., & Norton, P. J. (2008). Exploring the relationship between fear of positive evaluation and social anxiety. Journal of Anxiety Disorders, 22, 386–400. doi:10.1016/j.janxdis.2007.04.009.

    Article  PubMed  Google Scholar 

  • Weeks, J. W., & Howell, A. N. (2012). The bivalent fear of evaluation model of social anxiety: Further integrating findings on fears of positive and negative evaluation. Cognitive Behaviour Therapy, 41, 83–95. doi:10.1080/16506073.2012.661452.

    Article  PubMed  Google Scholar 

  • Weisbrot, D. M., Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child & Adolescent Psychopharmacology, 15, 477–496. doi:10.1089/cap.2005.15.477.

    Article  Google Scholar 

  • Weiss, J. A., Viecili, M. A., & Bohr, Y. (2014). Parenting stress as a correlate of cognitive behavior therapy responsiveness in children with autism spectrum disorders and anxiety. Focus on Autism and Other Developmental Disabilities. Advance online publication. doi:1088357614547808

    Google Scholar 

  • Weller, E. B., Weller, R. A., Teare, M., & Fristad, M. A. (1999). Parent version-children’s interview for psychiatric syndromes (P-ChIPS). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • White, S. W., Albano, A. M., Johnson, C. R., Kasari, C., Ollendick, T., Klin, A., … Scahill, L. (2010). Development of a cognitive-behavioral intervention program to treat anxiety and social deficits in teens with high-functioning autism. Clinical Child and Family Psychology Review, 13, 77–90. doi:10.1007/s10567-009-0062-3

    Google Scholar 

  • White, S. W., Lerner, M. D., McLeod, B. D., Wood, J. J., Ginsburg, G. S., Kerns, C., … Compton, S. (2015). Anxiety in youth with and without autism spectrum disorder: Examination of factorial equivalence. Behavior Therapy, 46, 40–53. doi:10.1016/j.beth.2014.05.005

    Google Scholar 

  • White, S. W., Maddox, B. B., & Panneton, R. K. (2015). Fear of negative evaluation influences eye gaze in adolescents with autism spectrum disorder: A pilot study. Journal of Autism and Developmental Disorders (Special Issue on Emotion Regulation and Psychiatric Comorbidity in ASD). Advance online publication. doi:10.1007/s10803-014-2349-6

  • White, S. W., Mazefsky, C. A., Dichter, G. S., Chiu, P. H., Richey, J. A., & Ollendick, T. H. (2014). Social-cognitive, physiological, and neural mechanisms underlying emotion regulation impairments: Understanding anxiety in autism spectrum disorder. International Journal of Developmental Neuroscience, 39, 22–36. doi:10.1016/j.ijdevneu.2014.05.012.

    Article  PubMed  PubMed Central  Google Scholar 

  • White, S. W., Ollendick, T., Albano, A. M., Oswald, D., Johnson, C., Southam-Gerow, M. A., … Scahill, L. (2013). Randomized controlled trial: Multimodal anxiety and social skill intervention for adolescents with autism spectrum disorder. Journal of Autism and Developmental Disorders, 43, 382–394. doi:10.1007/s10803-012-1577-x

    Google Scholar 

  • White, S. W., Oswald, D., Ollendick, T., & Scahill, L. (2009). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29, 216–229. doi:10.1016/j.cpr.2009.01.003.

    Article  PubMed  PubMed Central  Google Scholar 

  • White, S. W., & Roberson-Nay, R. (2009). Anxiety, social deficits, and loneliness in youth with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 1006–1013. doi:10.1007/s10803-009-0713-8.

    Article  PubMed  Google Scholar 

  • White, S. W., & Schry, A. R. (2011). Social anxiety in adolescents on the autism spectrum. In C. A. Alfano & D. C. Beidel (Eds.), Social anxiety in adolescents and young adults: Translating developmental science into practice (pp. 183–201). Washington, DC: American Psychological Association.

    Google Scholar 

  • White, S. W., Schry, A. R., & Kreiser, N. L. (2014). Social worries and difficulties: Autism and/or social anxiety disorder? In T. E. Davis III, S. W. White, & T. H. Ollendick (Eds.), Handbook of autism and anxiety (pp. 121–136). New York, NY: Springer.

    Chapter  Google Scholar 

  • White, S. W., Schry, A. R., & Maddox, B. B. (2012). Brief report: The assessment of anxiety in high-functioning adolescents with autism spectrum disorder. Journal of Autism and Developmental Disorders, 42, 1138–1145. doi:10.1007/s10803-011-1353-3.

    Article  PubMed  Google Scholar 

  • Wigham, S., & McConachie, H. (2014). Systematic review of the properties of tools used to measure outcomes in anxiety intervention studies for children with autism spectrum disorders. PLoS One, 9, e85268. doi:10.1371/journal.pone.0085268.

    Article  PubMed  PubMed Central  Google Scholar 

  • Williamson, S., Craig, J., & Slinger, R. (2008). Exploring the relationship between measures of self-esteem and psychological adjustment among adolescents with Asperger syndrome. Autism, 12, 391–402. doi:10.1177/1362361308091652.

    Article  PubMed  Google Scholar 

  • Witwer, A. N., Lecavalier, L., & Norris, M. (2012). Reliability and validity of the Children’s Interview for Psychiatric Syndromes-Parent Version in autism spectrum disorders. Journal of Autism and Developmental Disorders, 42, 1949–1958. doi:10.1007/s10803-012-1442-y.

    Article  PubMed  Google Scholar 

  • Wood, J. J., Drahota, A., Sze, K., Har, K., Chiu, A., & Langer, D. A. (2009). Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: A randomized, controlled trial. Journal of Child Psychology and Psychiatry, 50, 224–234. doi:10.1111/j.1469-7610.2008.01948.x.

    Article  PubMed  Google Scholar 

  • Wood, J. J., & Gadow, K. D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology: Science and Practice, 17, 281–292. doi:10.1111/j.1468-2850.2010.01220.x.

    Article  Google Scholar 

  • Wu, M. S., McGuire, J. F., Arnold, E. B., Lewin, A. B., Murphy, T. K., & Storch, E. A. (2013). Psychometric properties of the Children’s Yale-Brown Obsessive Compulsive Scale in youth with autism spectrum disorders and obsessive-compulsive symptoms. Child Psychiatry and Human Development, 45, 201–211. doi:10.1007/s10578-013-0392-8.

    Article  Google Scholar 

  • Zainal, H., Magiati, I., Tan, J. W. L., Sung, M., Fung, D. S., & Howlin, P. (2014). A preliminary investigation of the Spence Children’s Anxiety Parent Scale as a screening tool for anxiety in young people with autism spectrum disorders. Journal of Autism and Developmental Disorders, 44, 1982–1994. doi:10.1007/s10803-014-2075-0.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Psychology, Virginia Tech, Blacksburg, VA, USA

    Brenna B. Maddox & Susan W. White

  2. Center for Autism Research, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Brenna B. Maddox

  3. A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA, USA

    Connor M. Kerns

  4. Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA

    Martin E. Franklin

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  1. Brenna B. Maddox
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  2. Connor M. Kerns
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  3. Martin E. Franklin
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  4. Susan W. White
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Correspondence to Brenna B. Maddox .

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  1. Department of Psychology, Louisiana State University, Baton Rouge, LA, USA

    Johnny L. Matson

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Maddox, B.B., Kerns, C.M., Franklin, M.E., White, S.W. (2016). Anxiety Disorders and Obsessive-Compulsive Disorders (OCD). In: Matson, J.L. (eds) Handbook of Assessment and Diagnosis of Autism Spectrum Disorder. Autism and Child Psychopathology Series. Springer, Cham. https://doi.org/10.1007/978-3-319-27171-2_13

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