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Modeling Astrocyte-Neuron Interactions

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Neural Information Processing (ICONIP 2015)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 9491))

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Abstract

The involvement of astrocytes in information processing in the brain has recently been demonstrated. In this paper, we investigate, using computational models (SOM and MLP), one of the observed astrocyte-neuron interactions for information processing: the neural modulation represented by the observed calcium waves. We apply it to solve classification problems. The results of the performed tests confirmed that the proposed approach improved artificial neural network performance, especially learning time acceleration.

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References

  1. Verkhratsky, A., Kirchhoff, F.: Glutamate-mediated neuronal-glial transmission. J. Anat. 210, 651–660 (2007)

    Article  Google Scholar 

  2. Fields, R.D., Stevens, B.: ATP: an extracellular signaling molecule between neurons and glia. Trends Neurosci. 23, 625–633 (2000)

    Article  Google Scholar 

  3. Fields, R.D., Burnstock, G.: Purinergic signalling in neuron-glia interactions. Nat. Rev. Neurosci. 7, 423–436 (2006)

    Article  Google Scholar 

  4. Wigley, R., Hamilton, N., Nishiyama, A., Kirchhoff, F., Butt, A.M.: Morphological and physiological interactions of NG2-glia with astrocytes and neurons. J. Anat. 210, 661–670 (2007)

    Article  Google Scholar 

  5. Cornell-Bell, A.H., Finkbeiner, S.M., Cooper, M.S., Smith, S.J.: Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling. Science 247, 470–473 (1990)

    Article  Google Scholar 

  6. Haydon, P.J.: Glia: listening and talking to the synapse. Nat. Rev. Neurosci. 2, 185–193 (2001)

    Article  Google Scholar 

  7. Zonta, M., Angulo, M.C., Gobbo, S., et al.: Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat. Neurosci. 6, 43–50 (2003)

    Article  Google Scholar 

  8. Perea, G., Araque, A.: Synaptic information processing by astrocytes. J. Physiol. 99, 92–97 (2006)

    Google Scholar 

  9. Nedergaard, M., Ransom, B., Goldman, S.A.: New role for astrocytes: redefining the functional architecture of the brain. Rev. Trends Neurosci. 26, 523–530 (2003)

    Article  Google Scholar 

  10. Venance, L., Stella, N., Glowinski, J., Giaume, C.: Mechanism of initiation and propagation of receptor induced intercellular calcium signaling in cultured at astrocytes. J. Neurosci. 17, 1981–1992 (1997)

    Google Scholar 

  11. Kohonen, T.: The self-organizing map. Proc. IEEE 78, 1464–1480 (1990)

    Article  Google Scholar 

  12. Rumelhart, D.E., Hinton, G.E., Williams, R.J.: Learning representations by back-propagating errors. Nature 323–9, 533–536 (1986)

    Article  Google Scholar 

  13. Ikuta, C., Uwate, Y., Nishio, Y.: Chaos glial network connected to multi-layer perceptron for solving two-spiral problem. In: Proceedings of the ISCAS 2010, pp. 1360–1363 (2010)

    Google Scholar 

  14. Ikuta, C., Uwate, Y., Nishio, Y.: Parameter dependency of chaos glial network connected to multi-layer perceptron. In: Proceedings of the NCSP 2010, pp. 596–599 (2010)

    Google Scholar 

  15. Ikuta, C., Uwate, Y., Nishio, Y.: Multi-layer perceptron with impulse glial network. In: Proceedings of the NCN 2010, pp. 9–11 (2010)

    Google Scholar 

  16. Ikuta, C., Uwate, Y., Nishio, Y.: Multi-layer perceptron with glial network influenced by local external stimulus. In: Proceedings of the NCSP 2011, China, pp. 199–202 (2011)

    Google Scholar 

  17. Ikuta, C., Uwate, Y., Nishio, Y.: Performance and features of multi-layer perceptron with impulse glial network. In: Proceedings of the IJCNN 2011, pp. 2536–2541 (2011)

    Google Scholar 

  18. Ikuta, C., Uwate, Y., Nishio, Y.: Multi-layer perceptron with pulse glial chain. In: International Symposium on Nonlinear Theory and its Applications, NOLTA 2011, Japan, pp. 435–438 (2011)

    Google Scholar 

  19. Ikuta, C., Uwate, Y., Nishio, Y.: Multi-layer perceptron with pulse glial chain for solving two-spiral problem. In: IEEE Workshop on Nonlinear Circuit Networks, pp. 51–53 (2011)

    Google Scholar 

  20. Ikuta, C., Uwate, Y., Nishio, Y.: Investigation of Multi-layer perceptron with propagation of glial pulse to two directions. In: Proceedings of the ISCAS 2012, pp. 2099–2102 (2012)

    Google Scholar 

  21. Ikuta, C., Uwate, Y., Nishio, Y.: Multi-layer perceptron with positive and negative pulse glial chain for solving two-spiral problem. In: IEEE World Congress on Computational Intelligence, WCCI 2012, Australia, pp. 2590–2595 (2012)

    Google Scholar 

  22. Porto-Pazos, A.B., Veiguela, N., Mesejo, P., et al.: Artificial astrocytes improve neural network performance. PLoS ONE 6(4), e19109 (2011)

    Article  Google Scholar 

  23. Alvarellos-González, A., Pazos, A., Porto-Pazos, A.B.: Computational models of neuron-astrocyte interactions lead to improved efficacy in the performance of neural networks. Comput. Math. Methods Med., Article ID 476324, 10 (2012)

    Google Scholar 

  24. UCI machine learning repository. http://www.ics.uci.edu/~mlearn/MLRepository.html

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Correspondence to Soukeina Ben Chikha or Kirmene Marzouki .

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Ben Chikha, S., Marzouki, K., Ben Ahmed, S. (2015). Modeling Astrocyte-Neuron Interactions. In: Arik, S., Huang, T., Lai, W., Liu, Q. (eds) Neural Information Processing. ICONIP 2015. Lecture Notes in Computer Science(), vol 9491. Springer, Cham. https://doi.org/10.1007/978-3-319-26555-1_35

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  • DOI: https://doi.org/10.1007/978-3-319-26555-1_35

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-26554-4

  • Online ISBN: 978-3-319-26555-1

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