Abstract
There are many reasons to suppose that the interest to the nanoparticles will have remain for a long time, and the first one is that the nanoparticles have unique properties due to their intermediate state between atom-molecular and condensed matter. Object of investigation was the interaction of nanostructures water dispersions and biological objects—standard human blood serum and chicken egg white lysozyme . Measurements of nanostructures (from here and then monomers are smallest oxide nanoparticles, clusters are nanoparticles aggregations, supramolecular complexes are aggregations of nanostructures, albumins, and lipoproteins) sizes by means of the laser correlation spectrometer of quasi-elastic light scattering were carried out. Except laser correlation spectrometer at investigation, transmissive electronic microscopy, and atomic force microscopy were used. Interactions of nanostructure of all investigated metals with blood serum are of same type and have differed only quantitatively. These distinctions are connected with sizes of nanostructures aggregates. Correlation between patient state and blood properties allows us to suppose potential diagnostic significance of new integral characteristics of patient state, characteristic radii of nanoparticles-serum components complex formed. Obtained results and data available from publications, lead us to possibility of using such nanostructures for diagnosis of some conformational diseases.
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Kolikov, V., Rutberg, P. (2015). Interaction of the WDN with Biological Objects. In: Pulsed Electrical Discharges for Medicine and Biology. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-18129-5_8
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DOI: https://doi.org/10.1007/978-3-319-18129-5_8
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