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Trabecular Micro-Bypass Stent for the Treatment of Coexistent Cataract and Mild Open-Angle Glaucomas

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Advanced Glaucoma Surgery

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

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Abstract

In recent years, a strong interest in microinvasive glaucoma surgery (MIGS) has developed due to the significant complication rates associated with more traditional glaucoma filtering procedures. The first-generation trabecular micro-bypass stent (Glaukos iStent®) bypasses the trabecular meshwork, which is the site of highest outflow resistance in open angle glaucoma. In the United States, this device is currently approved to be implanted in conjunction with cataract extraction to lower the intraocular pressure (IOP) and decrease the medication burden load on patients with mild to moderate open angle glaucoma. This chapter summarizes the specifications and indications for this device as well as the clinical studies published on the iStent’s efficacy and safety. There have been multiple randomized controlled trials demonstrating a significant drop in IOP and postoperative medication use while maintaining an excellent safety profile. In all the studies, there have been no serious adverse events directly associated with the device. Recently, Glaukos has developed a new model of the iStent, which is currently undergoing investigational studies, but shows promise in lowering the IOP even further.

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Acknowledgements

Conflicts of Interest: Wanda D. Hu declares that she has no conflict of interest. Marlene R. Moster is a consultant for Glaukos.

Animal Studies: No animal or human studies were carried out by the authors for this article.

Informed Consent: Informed consent was not applicable for this article.

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Authors and Affiliations

  1. Miramar Eye Specialists Medical Group, Ventura, CA, 93003, USA

    Wanda D. Hu M.D.

  2. Glaucoma Division, Wills Eye Hospital, Philadelphia, PA, 19107, USA

    Marlene R. Moster M.D.

Authors
  1. Wanda D. Hu M.D.
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  2. Marlene R. Moster M.D.
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Corresponding author

Correspondence to Wanda D. Hu M.D. .

Editor information

Editors and Affiliations

  1. Illinois Eye & Ear Infirmary, University of Illinois at Chicago School of Medicine, Chicago, Illinois, USA

    Ahmad A. Aref

  2. Southern California, LA, CA, USA, USC Eye Ins.Dept. of Ophth. Univ.of Southern California, LA, CA, USA, California, California, USA

    Rohit Varma

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Hu, W.D., Moster, M.R. (2015). Trabecular Micro-Bypass Stent for the Treatment of Coexistent Cataract and Mild Open-Angle Glaucomas. In: Aref, A., Varma, R. (eds) Advanced Glaucoma Surgery. Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-18060-1_2

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  • DOI: https://doi.org/10.1007/978-3-319-18060-1_2

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18059-5

  • Online ISBN: 978-3-319-18060-1

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