Abstract
The intrahepatic cholangiocarcinoma (iCC) can present as single or multiple lesions tending to coalescence [1]. There are no wide study populations in literature about cholangiocarcinomas evaluated by means of CEUS, but according to reported data, the iCC presents inhomogeneous, mainly peripheral, contrast enhancement in the arterial phase with substantially hypovascular appearance in the extended portal-venous phase. The CEUS findings of ICC relate to the degree of neoplastic cell proliferation at pathological examination. Hyperenhancing areas in the tumor always indicated increased density of cancer cells. On the other side, fibrosis is more extended where hypovascular areas are detected [2]. Moreover, CEUS can definitely better delineate margins and evaluate more accurately the size and the possible involvement of the adjacent structures [3].
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Bartolotta, T.V., Taibbi, A., Midiri, M. (2015). Malignant Focal Liver Lesions. In: Atlas of Contrast-enhanced Sonography of Focal Liver Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-17539-3_3
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DOI: https://doi.org/10.1007/978-3-319-17539-3_3
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-17538-6
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