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Introduction to the B-Cell Lymphomas

  • Chapter
Atlas of Cutaneous Lymphomas

Abstract

The human body contains a vast array of B cells, with phenotypes ranging from the naïve B cell to the centrocyte, centroblast, immunoblast, plasmablast, and plasma cell. Each of these B-cell subsets has different functional, proliferative, and migratory capacities, and the diversity of cutaneous B-cell lymphoma (CBCL) reflects the variety of non-neoplastic B-cell counterparts. The WHO-EORTC classification [1] recognizes four cutaneous B-cell lymphomas: primary cutaneous marginal zone lymphoma (pcMZL or MALT lymphoma), primary cutaneous follicle-center lymphoma (pcFCL), primary cutaneous diffuse large B-cell lymphoma, leg-type (pcDLBCL), and intravascular large B-cell lymphoma (ivLBCL). Here we offer a schema for understanding and distinguishing these lymphomas. Each lymphoma is addressed individually in subsequent chapters.

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Correspondence to Lyn McDivitt Duncan M.D. .

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Goyal, A., Sohani, A.R., Kovach, A.E., Carter, J.B., Barnes, J.A., Duncan, L.M. (2015). Introduction to the B-Cell Lymphomas. In: Carter, J., Goyal, A., McDivitt Duncan, L. (eds) Atlas of Cutaneous Lymphomas. Springer, Cham. https://doi.org/10.1007/978-3-319-17217-0_15

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  • DOI: https://doi.org/10.1007/978-3-319-17217-0_15

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17216-3

  • Online ISBN: 978-3-319-17217-0

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