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Circadian Synchronization of Cognitive Functions

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Psychiatry and Neuroscience Update

Abstract

Animals, human beings among them, can adapt their behavior to (predictable) temporal fluctuations in the environment (such as day and night alternation, food and water availability, or social contact) by learning and memory processes interacting with an endogenous circadian clock. Behavioral, physiological, and biochemical circadian rhythms are crucial for the good mental health of an individual and rely on the integrity and functioning of the circadian system. The master clock in the suprachiasmatic nucleus synchronizes independent circadian peripheral clocks, localized in other brain areas, organs, and tissues to the appropriate phases by neural and humoral signals. Thus, circadian clocks orchestrate interactions between the organism’s internal processes and the environment in healthy, but also in pathological, conditions. This chapter focuses on the main components of the circadian system; the temporal organization of cognitive functions at the molecular, biochemical, and behavioural levels and their clock-mediated regulation; as well as on factors that could disrupt the normal functioning of the circadian system and thus, contribute to the etiology of cognitive disorders.

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Authors and Affiliations

  1. Laboratory of Chronobiology, Multidisciplinary Institute of Biological Research-San Luis (IMIBIO-SL), National Council for Science and Technology—National University of San Luis (CONICET-UNSL), Ejercito de los Andes 951, D5700HHW, San Luis, Argentina

    Ana Cecilia Anzulovich-Miranda Ph.D.

  2. Faculty of Chemistry Biology and Pharmacy (FQByF), National University of San Luis (UNSL), San Luis, Argentina

    Ana Cecilia Anzulovich-Miranda Ph.D.

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  1. Ana Cecilia Anzulovich-Miranda Ph.D.
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Correspondence to Ana Cecilia Anzulovich-Miranda Ph.D. .

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  1. Guaymallen Mendoza, Argentina

    Pascual Ángel Gargiulo

  2. Member of the Council of the Institute of Neurobiology (Buenos Aires); Member of the Board of Certification, National Academy of Medicine (Argentina), Psychiatrist by University Complutense of Madrid and University of Buenos Aires; Former Director of National Institute of Mental Health (Argentina), Cuyo, Buenos Aires, Argentina

    Humberto Luis Mesones Arroyo

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Anzulovich-Miranda, A.C. (2015). Circadian Synchronization of Cognitive Functions. In: Gargiulo, P., Arroyo, H. (eds) Psychiatry and Neuroscience Update. Springer, Cham. https://doi.org/10.1007/978-3-319-17103-6_11

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