Abstract
In isocratic elution chromatography, a modifier is often added to the mobile phase in order to compete with sample solutes for binding sites in the stationary phase [1]. This helps to reduce the retention time and band spreading of the sample solutes.
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Gu, T. (2015). System Peaks in Multicomponent Elution. In: Mathematical Modeling and Scale-Up of Liquid Chromatography. Springer, Cham. https://doi.org/10.1007/978-3-319-16145-7_7
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DOI: https://doi.org/10.1007/978-3-319-16145-7_7
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