Abstract
Another major category of nanoparticles are quantum dots (QDs), which are semiconductor nanocrystals (~2–100 nm) with unique optical and electrical properties, and widely used in biomedical imaging and the electronics industries [1–9]. These II–VI semiconductor nanostructures (II = Zn, Cd; VI = O, S, Se, Te) display outstanding properties distinct from their bulk counterparts like broad excitation bands, large extinction coefficient, tunable emission features, bright photoluminescence, nonlinear optical properties, and high stability against photobleaching and chemicals due to the quantum nano-confinement.
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References
Bruchez M, Moronne M, Gin P, Weiss S, Alivisatos AP (1998) Semiconductor nanocrystals as fluorescent biological labels. Science 281:2013–2016
Tessler N, Medvedev V, Kazes M, Kan S, Banin U (2002) Efficient near-infrared polymer nanocrystal light-emitting diodes. Science 295:1506–1508
Gorman J, Hasko DG, Williams DA (2005) Charge-qubit operation of an isolated double quantum dot. Phys Rev Lett 95:090502
Csonka S, Weymann I, Zarand G (2012) An electrically controlled quantum dot based spin current injector. Nanoscale 4:3635–3639
Lek JY, Xi L, Kardynal BE, Wong LH, Lam YM (2011) Understanding the effect of surface chemistry on charge generation and transport in Poly (3-hexylthiophene)/CdSe hybrid solar cells. ACS Appl Mater Interf 3:287–292
Kamat PV (2008) Quantum dot solar cells. semiconductor nanocrystals as light harvesters. J Phys Chem C 112:18737–18753
Lokteva I, Radychev N, Witt F, Borchert H, Parisi J, Kolny-Olesiak J (2010) Surface treatment of CdSe nanoparticles for application in hybrid solar cells: the effect of multiple ligand exchange with pyridine. J Phys Chem C 114:12784–12791
Gerion D, Pinaud F, Williams SC, Parak WJ, Zanchet D, Weiss S, Alivisatos AP (2001) Synthesis and properties of biocompatible water-soluble silica-coated CdSe/ZnS semiconductor quantum dots. J Phys Chem B 105:8861–8871
Tryk DA, Fujishima A, Honda K (2000) Recent topics in photoelectrochemistry: achievements and future prospects. Electrochim Acta 45:2363–2376
Alivisatos AP (1996) Semiconductor clusters, nanocrystals, and quantum dots. Science 271:933–937
Pandey A, Guyot-Sionnest P (2008) Slow electron cooling in colloidal quantum dots. Science 322:929–932
Murray CB, Norris DJ, Bawendi MG (1993) Synthesis and characterization of nearly monodisperse CdE (E = sulfur, selenium, tellurium) semiconductor nanocrystallites. J Am Chem Soc 115:8706–8715
Shiohara A, Prabakar S, Faramus A, Hsu CY, Lai PS, Northcote PT, Tilley RD (2011) Sized controlled synthesis, purification, and cell studies with silicon quantum dots. Nanoscale 3:3364–3370
Qu LH, Peng XG (2002) Control of photoluminescence properties of CdSe nanocrystals in growth. J Am Chem Soc 124:2049–2055
Scholes GD, Rumbles G (2006) Excitons in nanoscale systems. Nat Mater 5:683–696
Beard M, Midgett A, Law M, Ellingson R, Nozik A (2009) Variations in the quantum efficiency of multiple exciton generation for a series of chemically treated PbSe nanocrystal films. Nano Lett 9:1217–1222
Kang SG et al (2012) Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@ C82 (OH)22 and its implication for de novo design of nanomedicine. PNAS 109:15431–15436. See the Supporting Information for full reference
Kang SG, Huynh T, Zhou RH (2012) Non-destructive inhibition of metallofullerenol Gd@ C82 (OH)22 on WW domain: implication on signal transduction pathway. Sci Rep 2:00957
Hardman R (2006) A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect 114:165–172
Lovrić J et al (2005) Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots. J Mol Med (Berl) 83:377–385
Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sun-daresan G, Wu AM, Gambhir SS, Weiss S (2005) Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307:538–544
Medintz IL, Uyeda HT, Goldman ER, Mattoussi H (2005) Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 4:435–446
Gill R, Zayats M, Willner I (2008) Semiconductor quantum dots for bioanalysis. Angew Chem Int Ed 47:7602–7625
Kumar CSSR (2008) Nanomaterials for medical applications. Kirk-Othmer Encyclopedia of Chemical Technology, Wiley, 2007. http://mrw.interscience.wiley.com/emrw/9780471238966/kirk/article/nanokuma.a01/current/abstract. Accessed 11 Feb 2008
Drbohlavova J, Adam V, Kizek R, Hubalek J (2009) Quantum dots—characterization, preparation and usage in biological systems. J Mol Sci 10:656–673
Smith AM, Nie SM (2009) Next-generation quantum dots. Nat Biotechnol 27:732–733
Smith AM, Nie SM (2008) Minimizing the hydrodynamic size of quantum dots with multifunctional multidentate polymer ligands. J Am Chem Soc 130:11278–11279
Wang Y, Liu YH, Zhang Y, Wang F, Kowalski PJ, Rohrs HW, Loomis RA, Gross ML, Buhro WE (2012) Isolation of the magic-size CdSe nanoclusters [(CdSe)13(n-octylamine)13] and [(CdSe)13(oleylamine)13]. Angew Chem Int Ed 51:6154–6157
Walling MA, Novak JA, Shepard JRE (2009) Quantum dots for live cell and in vivo imaging. J Mol Sci 10:441–491
Chung SY, Lee S, Liu C, Neuhauser D (2009) Structures and electronic spectra of CdSe−Cys complexes: density functional theory study of a simple peptide-coated nanocluster. J Phys Chem B 113:292–301
Kim H, Jang SW, Chung SY, Lee S (2010) Effects of bioconjugation on the structures and electronic spectra of CdSe: density functional theory study of CdSe-Adenine complexes. J Phys Chem B 114:471–479
Albert VV, Ivanov SA, Tretiak S, Kilina SV (2011) Electronic structure of ligated CdSe clusters: dependence on DFT methodology. J Phys Chem C 115:15793–15800
Evans CM, Guo L, Peterson JJ, Maccagnano ZS, Krauss TD (2008) Ultrabright PbSe magic-sized clusters. Nano Lett 8:2896–2899
Nag A, Hazarika A, Shanavas KV, Sharma SM, Dasgupta I, Sarma DD (2011) Crystal structure engineering by fine-tuning the surface energy: the case of CdE (E = S/Se) nanocrystals. J Phys Chem Lett 2:706–712
Gao Y, Zhou B, Kang S, Xin M, Yang P, Dai X, Wang Z, Zhou R (2014) Effect of ligands on characteristics of (CdSe)13 quantum dot. RSC Adv 4:27146–27151
Azpiroz JM, Matxain JM, Infante I, Lopez X, Ugalde JM (2013) A DFT/TDDFT study on the optoelectronic properties of the amine-capped magic (CdSe)13 nanocluster. Phys Chem Chem Phys 15:10996–11005
Kasuya A et al (2004) Ultra-stable nanoparticles of CdSe revealed from mass spectrometry. Nat Mater 3:99–102. See the Supporting Information for full reference
Schreuder MA, McBride JR, Dukes AD III, Sammons JA, Ro-senthal SJ (2009) Control of surface state emission via phosphonic acid modulation in ultrasmall CdSe nanocrystals: the role of ligand electronegativity. J Phys Chem C 113:8169–8176
Knowles K, Tice DB, McArthur EA, SolOMOn GC, Weiss EA (2009) Chemical control of the photoluminescence of CdSe quantum dot−organic complexes with a series of para-substituted aniline ligands. J Am Chem Soc 132:1041–1050
Eichkorn K, Ahlrichs R (1998) Cadmium selenide semiconductor nanocrystals: a theoretical study. Chem Phys Lett 288:235–242
Deglmann P, Ahlrichs R, Tsereteli K (2002) Theoretical studies of ligand-free cadmium selenide and related semiconductor clusters. J Chem Phys 116:1585–1597
Leung K, Whaley KB (1999) Surface relaxation in CdSe nanocrystals. J Chem Phys 110:11012–11022
Troparevsky MC, Chelikowsky JR (2001) Structural and electronic properties of CdS and CdSe clusters. J Chem Phys 114:943–946
Troparevsky MC, Kronik L, Chelikowsky JR (2003) Optical properties of CdSe quantum dots. J Chem Phys 119:2284–2287
Puzder A, Williamson AJ, Gygi F, Galli G (2004) Self-healing of CdSe nanocrystals: first-principles calculations. Phys Rev Lett 92:217401
Yang P, Tretiak S, Masunov A, Ivanov S (2008) Quantum chemistry of the minimal CdSe clusters. J Chem Phys 129:074709
Tian CJ, Xiu P, Meng Y, Zhao WY, Wang ZG, Zhou RH (2012) Enantiomerization mechanism of thalidomide and the role of water and hydroxide ions. Chem Eur J 18:14305–14313
Wang ZG, Yao MG, Pan SF, Jin MX, Liu BB, Zhang HX (2007) A barrierless process from physisorption to chemisorption of H2 molecules on light-element-doped fullerenes. J Phys Chem C 111:4473–4476
Dai X, Cheng C, Zhang W, Xin MS, Huai P, Zhang RQ, Wang ZG (2013) Defect induced electronic structure of uranofullerene. Sci Rep 3:1341
Svetlana K, Sergei I, Sergei T (2009) Effect of surface ligands on optical and electronic spectra of semiconductor nanoclusters. J Am Chem Soc 131:7717–7726
Kuznetsov AE, Balamurugan D, Skourtis SS, Beratan DN (2012) Structural and electronic properties of bare and capped CdnSen/CdnTen Nanoparticles (n = 6, 9). J Phys Chem C 116:6817–6830
Becke AD (1993) Density-functional thermochemistry. III. The role of exact exchange. J Chem Phys 98:5648–5652
Lee C, Yang W, Parr RG (1988) Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. Phys Rev B 37:785–789
Miehlich B, Savin A, Stoll H, Preuss H (1989) Results obtained with the correlation energy density functionals of becke and Lee, Yang and Parr. Chem Phys Lett 157:200–206
Nadler R, Sanz JF (2013) Simulating the optical properties of CdSe clusters using the RT-TDDFT approach. Theor Chem Acc 132:1–9
Yang P, Tretiak S, Ivanov S (2011) Influence of surfactants and charges on CdSe quantum dots. J Clust Sci 22:405–431
Wang XQ, Zeng Q, Shi J, Jiang G, Yang ML, Liu XY, Enrightb G, Yu K (2013) The structure and optical absorption of single source precursors for II–VI quantum dots. Chem Phys Lett 568–569:125–129
Bloom BP, Zhao LB, Wang Y, Waldeck DH (2013) Ligand-induced changes in the characteristic size-dependent electronic energies of CdSe nanocrystals. J Phys Chem B 117:22401–22411
Muzakir SK, Alias N, Yusoff MM, Jose R (2013) On the missing links in quantum dot solar cells: a DFT study on fluorophore oxidation and reduction processes in sensitized solar cells. Phys Chem Chem Phys 15:16275–16285
Del Ben M, Havenith RWA, Broer R, Stener M (2011) J Phys Chem C 115:16782–16796
Ditchfield R, Hehre WJ, Pople JA (1971) Self-consistent molecular-orbital methods. IX. An extended Gaussian-type basis for molecular-orbital studies of organic molecules. J Chem Phys 54:724–728
Marques MAL, Gross EKU (2004) Time-dependent density functional theory. Annu Rev Phys Chem 55:427–455
Frisch MJ et al (2013) Gaussian 09 Revision D.01, Wallingford CT. See the Supporting Information for full reference
Landes C, Braun M, Burda C, El-Sayed MA (2001) Observation of large changes in the band gap absorption energy of small CdSe nanoparticles induced by the adsorption of a strong hole acceptor. Nano Lett 1:667–670
Kalyuzhny G, Murray RW (2005) Ligand effects on optical properties of CdSe nanocrystals. J Phys Chem B 109:7012–7021
Peng A, Wickham J, Alivisatos AP (1998) Kinetics of II–VI and III–V colloidal semiconductor nanocrystal growth: focusing of size distributions. J Am Chem Soc 120:5343–5344
Margaret AH, Philippe GS (1996) Synthesis and characterization of strongly luminescing ZnS-capped CdSe nanocrystals. J Phys Chem 100:468–471
Nguyen KA, Day PN, Pachter R (2010) Understanding structural and optical properties of nanoscale CdSe magic-size quantum dots: insight from computational prediction. J Phys Chem C 114:16197–16209
Perdew JP, Burke K, Ernzerhof M (1996) Phys Rev Lett 77:3865–3868
Velde GT, Bickelhaupt FM, Baerends EJ, Guerra CF, Gisbergen SJAV, Snijders JG, Ziegler T (2001) J Comput Chem 22:931–967
Klamt A (1995) J Phys Chem 99:2224–2235
Cossi M, Rega N, Scalmani G, Barone V (2003) J Phys Chem 24:669–681
Kuznetsov AE, Balamurugan D, Skourtis SS, Beratan DN (2012) J Phys Chem C 116:6817–6830
Fischer SA, Crotty AM, Kilina SV, Ivanov SA, Tretiak S (2012) Nanoscale 4:904–914
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Zhou, R. (2015). Quantum Dots and Their Ligand Passivation. In: Modeling of Nanotoxicity. Springer, Cham. https://doi.org/10.1007/978-3-319-15382-7_8
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DOI: https://doi.org/10.1007/978-3-319-15382-7_8
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