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Nanoemulsion in Drug Targeting

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Targeted Drug Delivery : Concepts and Design

Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

Nanoemulsions are the versatile drug carriers with the combined benefits of a lipophilic carrier and nanoscale. It can be used for a range of purposes, i.e., from bioavailability enhancement to MDR modulation. In recent time it has also been investigated for its potential in drug targeting. The drug targeting through nanoemulsion can be due to the virtue of its physicochemical properties or imparted by surface modification. Nanoemulsions can be used for local targeting such as skin, lymphatic system, and lungs. Such targeting is due to size, surface charge, or lipophilicity of nanoemulsion but sometimes novel targeting ligands are also employed. The systemic targeting by nanoemulsions largely exploits EPR mechanism. However, ligand based targeting and in more recent targeting using physical stimuli is also getting popular. Apart from drug delivery, targeted nanoemulsions can also be unveiled for diagnostic purposes such as carrying radio contrast media for longer time.

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Authors and Affiliations

  1. Department of Pharmaceutics, Jamia Hamdard, New Delhi, India

    Sushama Talegaonkar & Lalit Mohan Negi

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  1. Sushama Talegaonkar
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  2. Lalit Mohan Negi
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Correspondence to Sushama Talegaonkar .

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  1. Institute of Chemical Technology, Department of Pharmaceutical Sciences and Technology, Mumbai, India

    Padma V. Devarajan

  2. National Institute of Pharmaceutical Education and Research (NIPER), Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, Mohali, Punjab, India

    Sanyog Jain

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Talegaonkar, S., Negi, L.M. (2015). Nanoemulsion in Drug Targeting. In: Devarajan, P., Jain, S. (eds) Targeted Drug Delivery : Concepts and Design. Advances in Delivery Science and Technology. Springer, Cham. https://doi.org/10.1007/978-3-319-11355-5_14

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