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Cell Engineering for Therapeutic Protein Production

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Animal Cell Culture

Part of the book series: Cell Engineering ((CEEN,volume 9))

Abstract

In order to meet the ever-growing demand for therapeutic proteins, high therapeutic protein productivity in mammalian cell culture is necessary. Cell engineering is one of the most effective and powerful ways to improve the production of therapeutic proteins. This chapter describes various strategies of engineering biotechnologically important mammalian cell lines, mainly Chinese hamster ovary (CHO) cells, to achieve high therapeutic protein productivity.

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  1. Department of Biological Sciences, KAIST, 335 Gwahak-ro, Yuseong-gu, Daejeon, 305-701, Republic of Korea

    Eric Baek, Che Lin Kim, Jin Hyoung Park & Gyun Min Lee

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  1. Eric Baek
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  3. Jin Hyoung Park
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  4. Gyun Min Lee
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Corresponding author

Correspondence to Gyun Min Lee .

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  1. University College Dublin, Dublin, Ireland

    Mohamed Al-Rubeai

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Baek, E., Kim, C.L., Park, J.H., Lee, G.M. (2015). Cell Engineering for Therapeutic Protein Production. In: Al-Rubeai, M. (eds) Animal Cell Culture. Cell Engineering, vol 9. Springer, Cham. https://doi.org/10.1007/978-3-319-10320-4_18

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