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Fetal MRI

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MRI of the Female and Male Pelvis

Abstract

Fetal MRI is a noninvasive method to study both fetal and maternal structures. MRI intervenes as a third-level exam, after the first- and second-level ultrasound imaging, with various aims: to confirm ultrasound diagnosis, to search for other possible associated anomalies, and to obtain the right information in order to do a prognostic prediction and give parents adequate counseling.

There is no agreement on what concerns the risks of fetal MRI, so it is advisable not to execute the exam during the first trimester and not to administer contrast medium, to reduce potential risks for the developing fetus.

MRI has been shown to be useful in the diagnosis of maternal diseases and complications during pregnancy such as gastrointestinal, renal, gynecological, and placental pathologies.

MRI can depict very well the central nervous system of the fetus and so it is possible to detect many problems such as ventriculomegaly, medium line malformations, corpus callosum and posterior fossa abnormalities, cerebral infections, or ischemic and hemorrhagic injuries.

Fetal magnetic resonance imaging is useful to diagnose fetal thoracic abnormalities that are a heterogeneous group of fetal lung diseases, including pulmonary hypoplasia, congenital pulmonary airway malformation (CPAM), bronchopulmonary sequestration (BPS), bronchogenic cyst, and congenital diaphragmatic hernia (CDH).

Since most abdominal pathologies are easily seen on prenatal ultrasound, the role of MRI in the abdomen is less clear than in the brain and in the thorax; therefore, magnetic resonance imaging can be used as a complementary imaging tool for the confirmation of ultrasonographic findings.

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References

  1. Reddy UM et al (2008) Prenatal imaging: ultrasonography and magnetic resonance imaging. Obstet Gynecol 112(1):145–157

    Article  PubMed Central  PubMed  Google Scholar 

  2. Wright C, Sibley CP, Baker PN (2010) The role of fetal magnetic resonance imaging. Arch Dis Child Fetal Neonatal Ed 95(2):F137–F141

    Article  CAS  PubMed  Google Scholar 

  3. Weston MJ (2010) Magnetic resonance imaging in fetal medicine: a pictorial review of current and developing indications. Postgrad Med J 86(1011):42–51, quiz 50

    Article  CAS  PubMed  Google Scholar 

  4. Glenn OA, Barkovich AJ (2006) Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 1. AJNR Am J Neuroradiol 27(8):1604–1611

    CAS  PubMed  Google Scholar 

  5. Shellock FG, Crues JV (2004) MR procedures: biologic effects, safety, and patient care. Radiology 232(3):635–652

    Article  PubMed  Google Scholar 

  6. Semelka RC (2010) Abdominal-pelvic MRI, 3rd edn. Wiley-Blackwell, Hoboken

    Google Scholar 

  7. Stone K (2002) Acute abdominal emergencies associated with pregnancy. Clin Obstet Gynecol 45(2):553–561

    Article  PubMed  Google Scholar 

  8. Spencer JA et al (2004) Evaluation of painful hydronephrosis in pregnancy: magnetic resonance urographic patterns in physiological dilatation versus calculous obstruction. J Urol 171(1):256–260

    Article  CAS  PubMed  Google Scholar 

  9. Coronado GD, Marshall LM, Schwartz SM (2000) Complications in pregnancy, labor, and delivery with uterine leiomyomas: a population-based study. Obstet Gynecol 95(5):764–769

    Article  CAS  PubMed  Google Scholar 

  10. Sherer DM et al (2000) Prenatal magnetic resonance imaging assisting in differentiating between large degenerating intramural leiomyoma and complex adnexal mass during pregnancy. J Matern Fetal Med 9(3):186–189

    CAS  PubMed  Google Scholar 

  11. Levine D et al (1997) Placenta accreta: evaluation with color Doppler US, power Doppler US, and MR imaging. Radiology 205(3):773–776

    Article  CAS  PubMed  Google Scholar 

  12. Masselli G et al (2011) MR imaging in the evaluation of placental abruption: correlation with sonographic findings. Radiology 259(1):222–230

    Article  PubMed  Google Scholar 

  13. Levine D, Barnes PD (1999) Cortical maturation in normal and abnormal fetuses as assessed with prenatal MR imaging. Radiology 210(3):751–758

    Article  CAS  PubMed  Google Scholar 

  14. Prayer D et al (2006) MRI of normal fetal brain development. Eur J Radiol 57(2):199–216

    Article  PubMed  Google Scholar 

  15. Glenn OA (2009) Normal development of the fetal brain by MRI. Semin Perinatol 33(4):208–219

    Article  PubMed  Google Scholar 

  16. Garel C (2004) MRI of the fetal brain, Ith edn. Springer, Berlin

    Book  Google Scholar 

  17. Parazzini C et al (2008) Prenatal magnetic resonance imaging: brain normal linear biometric values below 24 gestational weeks. Neuroradiology 50(10):877–883

    Article  CAS  PubMed  Google Scholar 

  18. Leitner Y et al (2009) The neurocognitive outcome of mild isolated fetal ventriculomegaly verified by prenatal magnetic resonance imaging. Am J Obstet Gynecol 201(2):215 e1–215 e6

    Article  Google Scholar 

  19. Gaglioti P, Oberto M, Todros T (2009) The significance of fetal ventriculomegaly: etiology, short- and long-term outcomes. Prenat Diagn 29(4):381–388

    Article  PubMed  Google Scholar 

  20. Garel C et al (2003) Ventricular dilatations. Childs Nerv Syst 19(7–8):517–523

    Article  PubMed  Google Scholar 

  21. Mehta TS, Levine D (2005) Imaging of fetal cerebral ventriculomegaly: a guide to management and outcome. Semin Fetal Neonatal Med 10(5):421–428

    Article  PubMed  Google Scholar 

  22. Kelly EN et al (2001) Mild ventriculomegaly in the fetus, natural history, associated findings and outcome of isolated mild ventriculomegaly: a literature review. Prenat Diagn 21(8):697–700

    Article  CAS  PubMed  Google Scholar 

  23. Griffiths PD et al (2010) A prospective study of fetuses with isolated ventriculomegaly investigated by antenatal sonography and in utero MR imaging. AJNR Am J Neuroradiol 31(1):106–111

    Article  CAS  PubMed  Google Scholar 

  24. Dill P et al (2009) Fetal magnetic resonance imaging in midline malformations of the central nervous system and review of the literature. J Neuroradiol 36(3):138–146

    Article  CAS  PubMed  Google Scholar 

  25. Hosseinzadeh K et al (2013) Non-visualisation of cavum septi pellucidi: implication in prenatal diagnosis? Insights Imaging 4(3):357–367

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  26. Volpe P et al (2006) Characteristics, associations and outcome of partial agenesis of the corpus callosum in the fetus. Ultrasound Obstet Gynecol 27(5):509–516

    Article  CAS  PubMed  Google Scholar 

  27. Garel C et al (2003) Fetal MRI: normal gestational landmarks for cerebral biometry, gyration and myelination. Childs Nerv Syst 19(7–8):422–425

    Article  PubMed  Google Scholar 

  28. Tang PH et al (2009) Agenesis of the corpus callosum: an MR imaging analysis of associated abnormalities in the fetus. AJNR Am J Neuroradiol 30(2):257–263

    Article  CAS  PubMed  Google Scholar 

  29. Bulas D (2010) Fetal evaluation of spine dysraphism. Pediatr Radiol 40(6):1029–1037

    Article  PubMed  Google Scholar 

  30. Chao TT et al (2010) Central nervous system findings on fetal magnetic resonance imaging and outcomes in children with spina bifida. Obstet Gynecol 116(2 Pt 1):323–329

    Article  PubMed  Google Scholar 

  31. Adamsbaum C et al (2005) MRI of the fetal posterior fossa. Pediatr Radiol 35(2):124–140

    Article  PubMed  Google Scholar 

  32. Epelman M et al (2006) Differential diagnosis of intracranial cystic lesions at head US: correlation with CT and MR imaging. Radiographics 26(1):173–196

    Article  PubMed  Google Scholar 

  33. Tortori-Donati P et al (1996) Cystic malformations of the posterior cranial fossa originating from a defect of the posterior membranous area. Mega cisterna magna and persisting Blake’s pouch: two separate entities. Childs Nerv Syst 12(6):303–308

    Article  CAS  PubMed  Google Scholar 

  34. Barkovich AJ, Girard N (2003) Fetal brain infections. Childs Nerv Syst 19(7–8):501–507

    Article  PubMed  Google Scholar 

  35. Soussotte C et al (2000) Contribution of transvaginal ultrasonography and fetal cerebral MRI in a case of congenital cytomegalovirus infection. Fetal Diagn Ther 15(4):219–223

    Article  CAS  PubMed  Google Scholar 

  36. Jelin AC et al (2008) Intracranial magnetic resonance imaging findings in the surviving fetus after spontaneous monochorionic cotwin demise. Am J Obstet Gynecol 199(4):398 e1–398 e5

    Article  Google Scholar 

  37. Quarello E, Molho M, Ville Y (2007) Incidence, mechanisms, and patterns of fetal cerebral lesions in twin-to-twin transfusion syndrome. J Matern Fetal Neonatal Med 20(8):589–597

    Article  PubMed  Google Scholar 

  38. Stroustrup Smith A et al (2004) Prenatal diagnosis of cleft lip and cleft palate using MRI. AJR Am J Roentgenol 183(1):229–235

    Article  CAS  PubMed  Google Scholar 

  39. Teksam M et al (2005) MR imaging and ultrasound of fetal cervical cystic lymphangioma: utility in antepartum treatment planning. Diagn Interv Radiol 11(2):87–89

    PubMed  Google Scholar 

  40. Shiraishi H et al (2000) Prenatal MRI in a fetus with a giant neck hemangioma: a case report. Prenat Diagn 20(12):1004–1007

    Article  CAS  PubMed  Google Scholar 

  41. Woodward PJ et al (2005) From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics 25(1):215–242

    Article  PubMed  Google Scholar 

  42. Biyyam DR et al (2010) Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics 30(6):1721–1738

    Article  PubMed  Google Scholar 

  43. Recio Rodriguez M et al (2012) MR imaging of thoracic abnormalities in the fetus. Radiographics 32(7):E305–E321

    Article  PubMed  Google Scholar 

  44. Barth RA (2012) Imaging of fetal chest masses. Pediatr Radiol 42(Suppl 1):S62–S73

    Article  PubMed  Google Scholar 

  45. Bush A (2009) Prenatal presentation and postnatal management of congenital thoracic malformations. Early Hum Dev 85(11):679–684

    Article  PubMed  Google Scholar 

  46. Vergani P (2012) Prenatal diagnosis of pulmonary hypoplasia. Curr Opin Obstet Gynecol 24(2):89–94

    Article  PubMed  Google Scholar 

  47. Sandrasegaran K, Lall CG, Aisen AA (2006) Fetal magnetic resonance imaging. Curr Opin Obstet Gynecol 18(6):605–612

    Article  PubMed  Google Scholar 

  48. Lakhoo K (2009) Management of congenital cystic adenomatous malformations of the lung. Arch Dis Child Fetal Neonatal Ed 94(1):F73–F76

    Article  CAS  PubMed  Google Scholar 

  49. Azizkhan RG, Crombleholme TM (2008) Congenital cystic lung disease: contemporary antenatal and postnatal management. Pediatr Surg Int 24(6):643–657

    Article  PubMed  Google Scholar 

  50. Kunisaki SM et al (2007) Large fetal congenital cystic adenomatoid malformations: growth trends and patient survival. J Pediatr Surg 42(2):404–410

    Article  PubMed  Google Scholar 

  51. Wilson RD et al (2006) Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatment. Am J Med Genet A 140(2):151–155

    Article  PubMed  Google Scholar 

  52. Alamo L et al (2012) Prenatal diagnosis of congenital lung malformations. Pediatr Radiol 42(3):273–283

    Article  PubMed  Google Scholar 

  53. Liu YP et al (2010) Fetal cystic lung lesions: evaluation with magnetic resonance imaging. Pediatr Pulmonol 45(6):592–600

    PubMed  Google Scholar 

  54. Williams HJ, Johnson KJ (2002) Imaging of congenital cystic lung lesions. Paediatr Respir Rev 3(2):120–127

    Article  CAS  PubMed  Google Scholar 

  55. Winters WD, Effmann EL (2001) Congenital masses of the lung: prenatal and postnatal imaging evaluation. J Thorac Imaging 16(4):196–206

    Article  CAS  PubMed  Google Scholar 

  56. Done E et al (2008) Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia. Prenat Diagn 28(7):581–591

    Article  PubMed  Google Scholar 

  57. Huisman TA, Kellenberger CJ (2008) MR imaging characteristics of the normal fetal gastrointestinal tract and abdomen. Eur J Radiol 65(1):170–181

    Article  PubMed  Google Scholar 

  58. Brugger PC, Prayer D (2006) Fetal abdominal magnetic resonance imaging. Eur J Radiol 57(2):278–293

    Article  PubMed  Google Scholar 

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Correspondence to Alessia Adami .

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Adami, A., Mehrabi, S., Zaccarella, A., Ventriglia, A., Manfredi, R., Mucelli, R.P. (2015). Fetal MRI. In: Manfredi, R., Pozzi Mucelli, R. (eds) MRI of the Female and Male Pelvis. Springer, Cham. https://doi.org/10.1007/978-3-319-09659-9_11

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  • DOI: https://doi.org/10.1007/978-3-319-09659-9_11

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