Abstract
The widespread use of CT imaging and the critical importance of early detection of epidural masses of the spinal canal generate a scenario ideal for the implementation of a computer-aided detection (CAD) system. Epidural masses can lead to paralysis, incontinence and loss of neurological function if not promptly detected. We present, to our knowledge, the first CAD system to detect epidural masses on CT. In this paper, global intensity and local spatial features are modeled as spatially constrained Gaussian Mixture Model (CGMM) for epidural mass detection. The Cross-validation on 23 patients with epidural masses on body CT showed that the CGMM yielded a marked improvement of performance (69 % at 8.6 false positives per patient) over an intensity based K-means method (46 % at 7.9 false-positives per patient).
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References
Schiff, D., O’Neill, B.P., et al.: Spinal epidural metastasis as the initial manifestation of malignancy: clinical features and diagnostic approach. Neurology 49(2), 452–456 (1997)
Hricak, H., Akin, O., Bradbury, M.S.: Functional and metabolic imaging. In: DeVita, V.T. (ed.) Cancer: Principles & Practice of Oncology, pp. 589–616. Williams & Wilkins, Baltimore (2005)
Fine, H., Barker, F.G., Markert, J.M., Loeffler, J.S.: Neoplasms of the central nervous system. Cancer: Principles & Practice of Oncology, pp. 1834–1887. Williams & Wilkins, Baltimore (2005)
Freifeld, O., Greenspan, H.: Multiple sclerosis lesion detection using constrained GMM and curve evolution. Int. J. Biomed. Imaging 2009, 14 (2009)
Jianhua, Y., O’Connor, S. D., et al.: Automated spinal column extraction and partitioning. In: 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, pp 390–393 (2006)
Haralick, R.M., Shanmugam, K., Dinstein, I.: Textural features for image classification. IEEE Trans. Syst. Man Cybern. 3, 610–621 (1973)
Yao, J., Summers, R.M., et al.: Optimizing the support vector machines (SVM) committee configuration in a colonic polyp CAD system. Proc. SPIE 5746, 384–392 (2005)
Carlson, J., Heckerman, D., Shani, G.: False discovery rate for 2x2 contingency tables. Microsoft Research technical report MSR-TR-2009-53 (2009)
Wang, Q.: HMRF-EM-image: implementation of the Hidden Markov random field model and its expectation-maximization algorithm. CoRR e-prints (1207.3510)
Dorwart, R.H., DeGroot, J., Sauerland, E.T., et al.: CT of the lumbar spine: normal variants and pitfalls. Radiographics 2(4), 459–499 (1982)
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Pattanaik, S. et al. (2014). Epidural Masses Detection on Computed Tomography Using Spatially-Constrained Gaussian Mixture Models. In: Yao, J., Klinder, T., Li, S. (eds) Computational Methods and Clinical Applications for Spine Imaging. Lecture Notes in Computational Vision and Biomechanics, vol 17. Springer, Cham. https://doi.org/10.1007/978-3-319-07269-2_9
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DOI: https://doi.org/10.1007/978-3-319-07269-2_9
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