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Functional Imaging of Internet Gaming Disorder

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Internet Addiction

Abstract

The present chapter reviews functional magnetic resonance imaging (fMRI) studies of Internet gaming disorder (IGD) and Internet addiction (IA). The review includes reports of the use of fMRI, including arterial spin-labeled fMRI for analyzing task-related performance, resting functional connectivity, and effective connectivity. However, any conclusions regarding the mechanisms of IGD or IA would be premature due to the many limitations of previous studies. Future work should consider the diagnostic criteria outlined in the DSM-5 when recruiting subjects with IGD. Further fMRI studies with adequate sample sizes of at least 20 participants, reasonable hypotheses, effective designs, and precise data analyses by integrated research teams are needed for further elucidation of the mechanisms of IGD and IA.

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References

  • American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edn. APA, Washington DC

    Google Scholar 

  • American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. APA, Arlington

    Book  Google Scholar 

  • Beard KW, Wolf EM (2001) Modification in the proposed diagnostic criteria for internet addiction. CyberPsychol Behav 4:377–383

    Article  Google Scholar 

  • Bonson KR, Grant SJ, Contoreggi CS et al (2002) Neural systems and cue-induced cocaine craving. Neuropsychopharmacology 26:376–386

    Article  Google Scholar 

  • Botvinick MM (2007) Conflict monitoring and decision making: reconciling two perspectives on anterior cingulate function. Cogn Affect Behav Neurosci 7:356–366

    Article  Google Scholar 

  • Cavanna AE, Trimble MR (2006) The precuneus: a review of its functional anatomy and behavioural correlates. Brain 129:564–583

    Article  Google Scholar 

  • Chiamulera C (2005) Cue reactivity in nicotine and tobacco dependence: a “multiple-action” model of nicotine as a primary reinforcement and as an enhancer of the effects of smoking-associated stimuli. Brain Res Rev 48:74–97

    Article  Google Scholar 

  • Corradi-Dell’acqua C, Ueno K, Ogawa A et al (2008) Effects of shifting perspective of the self: an fMRI study. Neuroimage 40:1902–1911

    Article  Google Scholar 

  • Criaud M, Boulinguez P (2013) Have we been asking the right questions when assessing response inhibition in go/no-go tasks with fMRI? A meta-analysis and critical review. Neurosci Biobehav Rev 37:11–23

    Article  Google Scholar 

  • Davis RA (2001) A cognitive-behavioral model of pathological internet use. Comput Hum Behav 17:187–195

    Article  Google Scholar 

  • Detre JA, Wang J, Wang Z, Rao H (2009) Arterial spin-labeled perfusion MRI in basic and clinical neuroscience. Curr Opin Neurol 22:348–355

    Article  Google Scholar 

  • Ding WN, Sun JH, Sun YW et al (2013) Altered default network resting-state functional connectivity in adolescents with internet gaming addiction. PLoS One 8:e59902

    Article  Google Scholar 

  • Dong G, Zhou H, Zhao X (2010) Impulse inhibition in people with internet addiction disorder: electrophysiological evidence from a Go/NoGo study. Neurosci Lett 485:138–142

    Article  Google Scholar 

  • Dong G, Huang J, Du X (2011) Enhanced reward sensitivity and decreased loss sensitivity in internet addicts: an fMRI study during a guessing task. J Psychiatr Res 45:1525–1529

    Article  Google Scholar 

  • Dong G, Huang J, Du X (2012a) Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts. Behav Brain Funct 8:41

    Article  Google Scholar 

  • Dong G, Devito EE, Du X, Cui Z (2012b) Impaired inhibitory control in ‘internet addiction disorder’: a functional magnetic resonance imaging study. Psychiatry Res Neuroimaging 203:153–158

    Article  Google Scholar 

  • Feng Q, Chen X, Sun J et al (2013) Voxel-level comparison of arterial spin-labeled perfusion magnetic resonance imaging in adolescents with internet gaming addiction. Behav Brain Funct 9:33

    Article  Google Scholar 

  • Fowler JS, Volkow ND, Kassed CA, Chang L (2007) Imaging the addicted human brain. Sci Pract Perspect 3:4–16

    Article  Google Scholar 

  • Friston KJ, Penny WD, Glaser DE (2005) Conjunction revisited. Neuroimage 25:661–667

    Article  Google Scholar 

  • Glover GH (2011) Overview of functional magnetic resonance imaging. Neurosurg Clin N Am 22:133–139

    Article  Google Scholar 

  • Goldman-Rakic P, Leung HC (2002) Functional architecture of the dorsolateral prefrontal cortex in monkeys and humans, in principles of frontal lobe function. Oxford University Press, Oxford

    Google Scholar 

  • Granic I, Lobel A, Engels RC (2014) The benefits of playing video games. Am Psychol 69:66–78

    Article  Google Scholar 

  • Han DH, Hwang JW, Renshaw PF (2010) Bupropion sustained release treatment decreases craving for video games and cue-induced brain activity in patients with internet video game addiction. Exp Clin Psychopharmacol 18:297–304

    Article  Google Scholar 

  • Heinz A, Beck A, Grusser SM et al (2009) Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addict Biol 14:108–118

    Article  Google Scholar 

  • Hong SB, Zalesky A, Cocchi L et al (2013) Decreased functional brain connectivity in adolescents with internet addiction. PLoS One 8:e57831

    Article  Google Scholar 

  • Huettel SA, Song AW, McCarthy G (2009) Functional magnetic resonance imaging, 2nd edn. Sinauer, Massachusetts

    Google Scholar 

  • Kilts CD, Schweitzer JB, Quinn CK et al (2001) Neural activity related to drug craving in cocaine addiction. Arch Gen Psychiatry 58:334–341

    Article  Google Scholar 

  • Kim EJ, Lee SY, Oh SG (2003) The validation of Korean adolescent internet addiction scale (K-AIAS). Korean J Clin Psychol 22:5

    Google Scholar 

  • Kim YR, Son JW, Lee SI et al (2012) Abnormal brain activation of adolescent internet addict in a ball-throwing animation task: possible neural correlates of disembodiment revealed by fMRI. Prog Neuropsychopharmacol Biol Psychiatry 39:88–95

    Article  Google Scholar 

  • Ko CH, Yen JY, Chen CC et al (2005a) Proposed diagnostic criteria of internet addiction for adolescents. J Nerv Ment Dis 193:728–733

    Article  Google Scholar 

  • Ko CH, Yen JY, Yen CF et al (2005b) Screening for internet addiction: an empirical study on cut-off points for the chen internet addiction scale. Kaohsiung J Med Sci 21:545–551

    Article  Google Scholar 

  • Ko CH, Yen JY, Chen CC et al (2006) Tridimensional personality of adolescents with internet addiction and substance use experience. Can J Psychiatry 51:887–894

    Google Scholar 

  • Ko CH, Yen JY, Yen CF et al (2007) Factors predictive for incidence and remission of internet addiction in young adolescents: a prospective study. CyberPsychol Behav 10:545–551

    Article  Google Scholar 

  • Ko CH, Yen JY, Yen CF et al (2008) The association between internet addiction and belief of frustration intolerance: the gender difference. CyberPsychol Behav 11:273–278

    Article  Google Scholar 

  • Ko CH, Liu GC, Hsiao S et al (2009a) Brain activities associated with gaming urge of online gaming addiction. J Psychiatry Res 43:739–747

    Article  Google Scholar 

  • Ko CH, Yen JY, Chen SH et al (2009b) Proposed diagnostic criteria and the screening and diagnosing tool of internet addiction in college students. Compr Psychiatry 50:378–384

    Article  Google Scholar 

  • Ko CH, Yen JY, Yen CF et al (2012) The association between internet addiction and psychiatric disorder: a review of the literature. Eur Psychiatry 27:1–8

    Article  Google Scholar 

  • Ko CH, Liu GC, Yen JY et al (2013a) Brain correlates of craving for online gaming under cue exposure in subjects with internet gaming addiction and in remitted subjects. Addict Biol 18:559–569

    Article  Google Scholar 

  • Ko CH, Liu GC, Yen JY et al (2013b) The brain activations for both cue-induced gaming urge and smoking craving among subjects comorbid with internet gaming addiction and nicotine dependence. J Psychiatry Res 47:486–493

    Article  Google Scholar 

  • Liu J, Gao XP, Osunde I et al (2010) Increased regional homogeneity in internet addiction disorder: a resting state functional magnetic resonance imaging study. Chin Med J 123:1904–1908

    Google Scholar 

  • Lorenz RC, Kruger JK, Neumann B et al (2013) Cue reactivity and its inhibition in pathological computer game players. Addict Biol 18:134–146

    Article  Google Scholar 

  • Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH (2003) An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19:1233–1239

    Article  Google Scholar 

  • Montag C, Weber B, Trautner P et al (2012) Does excessive play of violent first-person-shooter-video-games dampen brain activity in response to emotional stimuli? Biol Psychol 89:107–111

    Article  Google Scholar 

  • Montag C, Bey K, Sha P et al (2014) Is it meaningful to distinguish between generalized and specific Internet addiction? Evidence from a cross-cultural study from Germany, Sweden, Taiwan and China. Asia‐Pacific Psychiatry

    Google Scholar 

  • Mitchell DG (2011) The nexus between decision making and emotion regulation: a review of convergent neurocognitive substrates. Behav Brain Res 217:215–231

    Article  Google Scholar 

  • Murphy K, Garavan H (2004) An empirical investigation into the number of subjects required for an event-related fMRI study. Neuroimage 22:879–885

    Article  Google Scholar 

  • Nichols T, Brett M, Andersson J et al (2005) Valid conjunction inference with the minimum statistic. Neuroimage 25:653–660

    Article  Google Scholar 

  • Risinger RC, Salmeron BJ, Ross TJ et al (2005) Neural correlates of high and craving during cocaine self-administration using BOLD fMRI. Neuroimage 26:1097–1108

    Article  Google Scholar 

  • Rosazza C, Minati L (2011) Resting-state brain networks: literature review and clinical applications. Neurol Sci 32:773–785

    Article  Google Scholar 

  • Rudy JW (2009) Context representations, context functions, and the parahippocampal-hippocampal system. Learn Mem 16:573–585

    Article  Google Scholar 

  • Salzmann E, Vidyasagar TR, Creutzfeldt OD (1993) Functional comparison of neuronal properties in the primate posterior hippocampus and parahippocampus (area TF/TH) during different behavioural paradigms involving memory and selective attention. Behav Brain Res 53:133–149

    Article  Google Scholar 

  • Skinner MD, Aubin HJ (2010) Craving’s place in addiction theory: contributions of the major models. Neurosci Biobehav Rev 34:606–623

    Article  Google Scholar 

  • Sutherland MT, McHugh MJ, Pariyadath V, Stein EA (2012) Resting state functional connectivity in addiction: lessons learned and a road ahead. Neuroimage 62:2281–2295

    Article  Google Scholar 

  • Tao R, Huang X, Wang J et al (2010) Proposed diagnostic criteria for internet addiction. Addiction 105:556–564

    Article  Google Scholar 

  • Tejado Lde A, Ruiz RM, Trebbau H et al (2010) Functional magnetic resonance studies in eating behavior disorders. Actas Esp Psiquiatry 38:183–188

    Google Scholar 

  • Upadhyay J, Maleki N, Potter J et al (2010) Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. Brain 133:2098–2114

    Article  Google Scholar 

  • Volkow ND, Wang GJ, Fowler JS et al (2010) Addiction: decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain’s control circuit. BioEssays 32:748–755

    Article  Google Scholar 

  • Wang W, Tao R, Niu Y et al (2009) Preliminarily proposed diagnostic criteria of pathological internet use. Chin Ment Health J 23:5

    Google Scholar 

  • Widyanto L, McMurran M (2004) The psychometric properties of the internet addiction test. CyberPsychol Behav 7:443–450

    Article  Google Scholar 

  • Yeh YC, Ko HC, Wu JY, Cheng CP (2008) Gender differences in relationships of actual and virtual social support to internet addiction mediated through depressive symptoms among college students in Taiwan. CyberPsychol Behav 11:485–487

    Article  Google Scholar 

  • Young KS (1998) Caught in the net: how to recognize the signs of internet addiction and a winning strategy for recovery. Wiley, New York

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

    Chih-Hung Ko & Ju-Yu Yen

  2. Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

    Chih-Hung Ko & Ju-Yu Yen

  3. Department of Psychiatry, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

    Chih-Hung Ko

  4. Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

    Gin-Chung Liu

  5. Department of Medical Imaging, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

    Gin-Chung Liu

  6. Department of Psychiatry, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan

    Ju-Yu Yen

Authors
  1. Chih-Hung Ko
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  2. Gin-Chung Liu
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Correspondence to Chih-Hung Ko .

Editor information

Editors and Affiliations

  1. Universität Ulm, Molekulare Psychologie, Ulm, Germany

    Christian Montag

  2. Differentielle & Biologische Psychologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

    Martin Reuter

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Ko, CH., Liu, GC., Yen, JY. (2015). Functional Imaging of Internet Gaming Disorder. In: Montag, C., Reuter, M. (eds) Internet Addiction. Studies in Neuroscience, Psychology and Behavioral Economics. Springer, Cham. https://doi.org/10.1007/978-3-319-07242-5_3

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  • DOI: https://doi.org/10.1007/978-3-319-07242-5_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-07241-8

  • Online ISBN: 978-3-319-07242-5

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