Abstract
Large scale fed-batch operations are industrially important in agricultural and pharmaceutical sectors. In fed-batch operations, we need to optimize the flow rates of rate limiting substrates to maximize the required performance index. Dynamic optimization of the feed rate profiles renders the problem quite complex and requires intelligent techniques. In this context, evolutionary algorithms have proven to be very useful. We introduce the application of a fairly recent nature-inspired evolutionary optimization technique—biogeography-based optimization (BBO), not so widely known as other established evolutionary optimization techniques—for the fed-batch bioreactor-based dynamic optimization problems. We demonstrate with the help of two case studies that BBO can achieve performance indices in close agreement or better than the results in the literature for the considered problems.
(work done while the author was at Centre for Modeling and Simulation, University of Pune, India)
(work done while the author was at C-DAC, Pune, India)
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Acknowledgments
The authors acknowledge the Centre for Modeling and Simulation, University of Pune, India, and the Centre for Development of Advanced Computing, India, for their support. Also, VKJ gratefully acknowledges the Council of Scientific and Industrial Research (CSIR), New Delhi, India, for financial support.
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Nikumbh, S., Ghosh, S., Jayaraman, V.K. (2014). Biogeography-Based Optimization for Dynamic Optimization of Chemical Reactors. In: Valadi, J., Siarry, P. (eds) Applications of Metaheuristics in Process Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-06508-3_8
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