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Role of Pathology in the Multidisciplinary Management of Patients with Prostate Cancer

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Multidisciplinary Management of Prostate Cancer

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Abstract

A problem when handling radical prostatectomy specimens (RPS) is that prostate cancer is notoriously difficult to identify at gross examination, and the tumor extent is always underestimated by the naked eye. For the pathologist, the safest method to avoid undersampling of cancer is that the entire prostate is submitted. Even though whole mounts of sections from RPS appear not to be superior to sections from standard blocks in detecting adverse pathological features, their use has the great advantage of displaying the architecture of the prostate and the identification and location of tumour nodules more clearly, and make it easier to compare the pathological findings with those obtained from digital rectal examination (DRE), transrectal ultrasound (TRUS) and prostate biopsies.

This chapter is based on the Ancona (Italy) protocol for the evaluation of the RPS with complete sampling with whole mount sections.

The Ancona approach to the evaluation of the radical prostatectomies with special reference to the sampling and reporting of the prostate base/bladder neck and seminal vesicles.

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Author information

Authors and Affiliations

  1. Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Via Conca 71, 60126, Torrette, Ancona, Italy

    Rodolfo Montironi, Roberta Mazzucchelli & Marina Scarpelli

  2. Department of Surgery, Cordoba University Medical School, Cordoba, Spain

    Antonio Lopez-Beltran

  3. Division of Urology, “Murri” General Hospital, Fermo, ASUR Marche, Italy

    Andrea B. Galosi

  4. Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA

    Liang Cheng

Authors
  1. Rodolfo Montironi
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  2. Roberta Mazzucchelli
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  3. Marina Scarpelli
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  4. Antonio Lopez-Beltran
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  5. Andrea B. Galosi
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  6. Liang Cheng
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Corresponding author

Correspondence to Rodolfo Montironi .

Editor information

Editors and Affiliations

  1. Dept. of Urology, Sapienza University, Rome, Italy

    Vincenzo Gentile

  2. Department of Radiological Sciences, Oncology & Pathology, Sapienza University, Policlinico Umberto I, Latina, Italy

    Valeria Panebianco

  3. Dept. of Urology, Sapienza University, Rome, Italy

    Alessandro Sciarra

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© 2014 Springer International Publishing Switzerland

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Montironi, R., Mazzucchelli, R., Scarpelli, M., Lopez-Beltran, A., Galosi, A.B., Cheng, L. (2014). Role of Pathology in the Multidisciplinary Management of Patients with Prostate Cancer. In: Gentile, V., Panebianco, V., Sciarra, A. (eds) Multidisciplinary Management of Prostate Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-04385-2_4

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  • DOI: https://doi.org/10.1007/978-3-319-04385-2_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-04384-5

  • Online ISBN: 978-3-319-04385-2

  • eBook Packages: MedicineMedicine (R0)

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