Abstract
Adaptation to a cold environment changes the capacity of the autonomic and behavioural effector system and/or of the regulatory characteristics of the thermoregulatory system (1). The preoptic region of the anterior hypothalamus (PO/AH), known to be important in temperature regulation, contains a complex population of neurons that are sensitive to changes in local temperature (2). Besides it has been demonstrated that neuropeptides, e.g. bombesin and thyrotropin releasing hormone (TRH) change the temperature sensitivity of PO/AH neurons, resulting in an increase of the temperature coefficient (TC = imp • s-1 • °C-1) of warmsensitive (WS) and temperature insensitive (TI) neurons and a transformation of TI into WS neurons (3, 4).
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© 1994 Birkhäuser Verlag Basel
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Tzschentke, B., Schenda, J., Pierau, FK. (1994). Effects of Cold Adaptation on the Modulatory Action of TRH Upon Temperature Sensitive and Insensitive Hypothalamic Neurons of Rats. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_9
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DOI: https://doi.org/10.1007/978-3-0348-7429-8_9
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