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Lamina-Specific Effects of Nitric Oxide on Temperature Sensitive Neurons in Rat Spinal Cord Slices

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Thermal Balance in Health and Disease

Part of the book series: APS Advances in Pharmacological Sciences ((APS))

Abstract

The local temperature sensitivity of the spinal cord (SC) of various homeothermic species has clearly been established in in vivo experiments. Local temperature changes of the spinal cord elicit adequate heat loss and heat gain mechanisms, like vasoconstriction and shivering during cooling and vasodilation or panting during warming (1,2,3). The existence of temperature sensitive neurons within the spinal cord (3) has been demonstrated in in vivo and recent in vitro (4) experiments. In recordings from spinal cord slices, a comparable number of warm-sensitive and temperature insensitive neurons has been observed in neurons recorded in the superficial laminae I and n and around the central canal (lamina X). Cold-sensitive neurons have only been found in the latter region.

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© 1994 Birkhäuser Verlag Basel

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Pehl, U., Schmid, H.A., Simon, E. (1994). Lamina-Specific Effects of Nitric Oxide on Temperature Sensitive Neurons in Rat Spinal Cord Slices. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_6

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  • DOI: https://doi.org/10.1007/978-3-0348-7429-8_6

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7431-1

  • Online ISBN: 978-3-0348-7429-8

  • eBook Packages: Springer Book Archive

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