Abstract
There are several regions in the central nervous system which are known to be involved in temperature regulation, including the anterior hypothalamus and the spinal cord, where intrinsic temperature-sensitive neurones have been observed (for review: 1,2). The temperature sensitivity of these neurones is defined by a change in discharge rate to a given change of local temperature (1). We here report a temperature-sensitive neuronal mechanism, which appears to be independent from changes in firing rate. In the course of experiments conducted to characterize the temperature sensitivity of hypothalamic and spinal neurones in rats, occasionally recordings were obtained in which a regular spike was always preceded by one or more small spikes or by a hump in the rising phase (termed here pre-spike). The delay between these coupled events exhibited a marked temperature dependence.
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© 1994 Birkhäuser Verlag Basel
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Sann, H., Konrad, M., Pehl, U., Schmid, H.A., Pierau, FK., Simon, E. (1994). Temperature-Sensitive Coupling in Hypothalamic and Spinal Neurones of the Rat In Vitro. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_5
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DOI: https://doi.org/10.1007/978-3-0348-7429-8_5
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-0348-7431-1
Online ISBN: 978-3-0348-7429-8
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