Abstract
Wilhelm Siegmund Feldberg was born in Hamburg on the 19th November 1900. He graduated in medicine in Berlin in 1925 and then came to England where he worked as a visiting scientist with J.N. Langley and Joseph Barcroft in Cambridge and with Henry Dale at the National Institute for Medical Research in Hampstead. Thus began his scientific career in medical research, a career which he pursued for the rest of his life. On returning to Germany in 1982, he worked with E. Schilf on the role of histame in allergic reactions, which research lead to our understanding of the pathology of asthma; together they published a book in 1930 on histamine, which they dedicated to Dale.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Dashwood, M.R. and Feldberg, W. (1977) Endotoxin fever, prostaglandin and anaesthesia. In: Drugs, Biogenic amines and body temperature. Eds. Cooper, K.E., Lomax, P. and Schönbaum, E. pp. 145–152. Basel, Karger.
Dey, P.K., Feldberg, W., Gupta, K.P., Milton, A.S. and Wendlandt, S. (1974) Further studies on the role of prostaglandin in fever. J. Physiol. (Lond) 241, 629–646.
Feldberg, W. (1963) A pharmacological approach to the brain from its inner and outer surface. London, Edward Arnold (Publishers) Ltd.
Feldberg, W. (1977) The early history of synaptic and neuromuscular transmission by acetylcholine: reminiscences of an eye witness. In: The Pursuit of Nature, pp. 65–83. Cambridge, Cambridge University Press.
Feldberg, W., Gupta, K.P., Milton, A.S. and Wendlandt, S. (1973) Effect of pyrogen and antipyretics on prostaglandin activity in cisternal CSF on unanaesthetized cat. J. Physiol. (Lond) 234,279–303.
Feldberg, W. and Malcolm J.L. (1959) Experiments on the site of action of tubocurarine when applied via the cerebral ventricles. J. Physiol. (Lond) 149, 68–77.
Feldberg, W. and Milton, A.S. (1973) Prostaglandin fever, in: The Pharmacology of Thermoregulation. Eds. Lomax P. and Schönbaum, E. pp 302–310. Basel, Karger.
Feldberg, W. and Myers, R.D. (1964) Effects on temperature of amines injected into the cerebral ventricles. A new concept of temperature regulation. J. Physiol. (Lond) 173, 226–237.
Feldberg, W. and Myers, R.D. (1966) Appearance of 5-hydroxytryptamine and an unidentified pharmacologically active lipid acid in effluent from perfused cerebral ventricles. J. Physiol. (Lond) 184, 837–855.
Feldberg, W., Myers, R.D. and Veale, W.L. (1970) Perfusion from cerebral ventricle to cisterna magna in the unanaesthetized cat. Effect of calcium on body temperature. J. Physiol. (Lond) 207, 403–416
Feldberg, W., Pyke, D.A. and Stubbs, W.A. (1988) Hyper- and hypoglycaemia produced in anaesthetized cats by phentolamine. J. Physiol. (Lond) 407, 106p.
Feldberg, W. and Saxena, P.N. (1971) Fever produced by prostaglandin E1. J. Physiol. (Lond) 217, 547–556.
Feldberg, Wand Schilf E. (1930) Histamin. Berlin. Julius Springer.
Feldberg, W. and Scott, J.M. (1984) Interferon fever in cats. J. Physiol. (Lond) 355, 28P.
Milton, A.S. and Wendlandt, S. (1968) The effect of 4-acetamidophenol in reducing fever produced by the intracerebral injection of 5-hydrotryptamine and pyrogen in the conscious cat. Brit. J. Pharmacol. 34, 215P.
Milton, A.S. and Wendlandt, S. (1970) A possible role for prostaglandin E1 as a modulator for temperature regulation in the central nervous system in the cat. J. Physiol. (Lond) 207, 76–77P.
Vane, J.R. (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol. 23, 232–235.
Villablanca, J. and Myers, R.D. (1965) Fever produced by microinjection of typhoid vaccine into hypothalamus of cats. Am. J. Physiol. 208, 703–707.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Birkhäuser Verlag Basel
About this chapter
Cite this chapter
Milton, A.S. (1994). W.S. Feldberg — his Contribution to the Pharmacology of Thermoregulation. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_2
Download citation
DOI: https://doi.org/10.1007/978-3-0348-7429-8_2
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-0348-7431-1
Online ISBN: 978-3-0348-7429-8
eBook Packages: Springer Book Archive