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W.S. Feldberg — his Contribution to the Pharmacology of Thermoregulation

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Thermal Balance in Health and Disease

Part of the book series: APS Advances in Pharmacological Sciences ((APS))

Abstract

Wilhelm Siegmund Feldberg was born in Hamburg on the 19th November 1900. He graduated in medicine in Berlin in 1925 and then came to England where he worked as a visiting scientist with J.N. Langley and Joseph Barcroft in Cambridge and with Henry Dale at the National Institute for Medical Research in Hampstead. Thus began his scientific career in medical research, a career which he pursued for the rest of his life. On returning to Germany in 1982, he worked with E. Schilf on the role of histame in allergic reactions, which research lead to our understanding of the pathology of asthma; together they published a book in 1930 on histamine, which they dedicated to Dale.

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References

  1. Dashwood, M.R. and Feldberg, W. (1977) Endotoxin fever, prostaglandin and anaesthesia. In: Drugs, Biogenic amines and body temperature. Eds. Cooper, K.E., Lomax, P. and Schönbaum, E. pp. 145–152. Basel, Karger.

    Google Scholar 

  2. Dey, P.K., Feldberg, W., Gupta, K.P., Milton, A.S. and Wendlandt, S. (1974) Further studies on the role of prostaglandin in fever. J. Physiol. (Lond) 241, 629–646.

    CAS  Google Scholar 

  3. Feldberg, W. (1963) A pharmacological approach to the brain from its inner and outer surface. London, Edward Arnold (Publishers) Ltd.

    Google Scholar 

  4. Feldberg, W. (1977) The early history of synaptic and neuromuscular transmission by acetylcholine: reminiscences of an eye witness. In: The Pursuit of Nature, pp. 65–83. Cambridge, Cambridge University Press.

    Google Scholar 

  5. Feldberg, W., Gupta, K.P., Milton, A.S. and Wendlandt, S. (1973) Effect of pyrogen and antipyretics on prostaglandin activity in cisternal CSF on unanaesthetized cat. J. Physiol. (Lond) 234,279–303.

    CAS  Google Scholar 

  6. Feldberg, W. and Malcolm J.L. (1959) Experiments on the site of action of tubocurarine when applied via the cerebral ventricles. J. Physiol. (Lond) 149, 68–77.

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  7. Feldberg, W. and Milton, A.S. (1973) Prostaglandin fever, in: The Pharmacology of Thermoregulation. Eds. Lomax P. and Schönbaum, E. pp 302–310. Basel, Karger.

    Google Scholar 

  8. Feldberg, W. and Myers, R.D. (1964) Effects on temperature of amines injected into the cerebral ventricles. A new concept of temperature regulation. J. Physiol. (Lond) 173, 226–237.

    CAS  Google Scholar 

  9. Feldberg, W. and Myers, R.D. (1966) Appearance of 5-hydroxytryptamine and an unidentified pharmacologically active lipid acid in effluent from perfused cerebral ventricles. J. Physiol. (Lond) 184, 837–855.

    CAS  Google Scholar 

  10. Feldberg, W., Myers, R.D. and Veale, W.L. (1970) Perfusion from cerebral ventricle to cisterna magna in the unanaesthetized cat. Effect of calcium on body temperature. J. Physiol. (Lond) 207, 403–416

    CAS  Google Scholar 

  11. Feldberg, W., Pyke, D.A. and Stubbs, W.A. (1988) Hyper- and hypoglycaemia produced in anaesthetized cats by phentolamine. J. Physiol. (Lond) 407, 106p.

    Google Scholar 

  12. Feldberg, W. and Saxena, P.N. (1971) Fever produced by prostaglandin E1. J. Physiol. (Lond) 217, 547–556.

    CAS  Google Scholar 

  13. Feldberg, Wand Schilf E. (1930) Histamin. Berlin. Julius Springer.

    Google Scholar 

  14. Feldberg, W. and Scott, J.M. (1984) Interferon fever in cats. J. Physiol. (Lond) 355, 28P.

    Google Scholar 

  15. Milton, A.S. and Wendlandt, S. (1968) The effect of 4-acetamidophenol in reducing fever produced by the intracerebral injection of 5-hydrotryptamine and pyrogen in the conscious cat. Brit. J. Pharmacol. 34, 215P.

    CAS  Google Scholar 

  16. Milton, A.S. and Wendlandt, S. (1970) A possible role for prostaglandin E1 as a modulator for temperature regulation in the central nervous system in the cat. J. Physiol. (Lond) 207, 76–77P.

    Google Scholar 

  17. Vane, J.R. (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol. 23, 232–235.

    Google Scholar 

  18. Villablanca, J. and Myers, R.D. (1965) Fever produced by microinjection of typhoid vaccine into hypothalamus of cats. Am. J. Physiol. 208, 703–707.

    PubMed  CAS  Google Scholar 

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© 1994 Birkhäuser Verlag Basel

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Milton, A.S. (1994). W.S. Feldberg — his Contribution to the Pharmacology of Thermoregulation. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_2

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  • DOI: https://doi.org/10.1007/978-3-0348-7429-8_2

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7431-1

  • Online ISBN: 978-3-0348-7429-8

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