Abstract
Many drugs such as ethanol act centrally to alter the processes of thermoregulation. The magnitude of the effect of ethanol depends on both dose and ambient temperature. At ambient temperatures below the thermoneutrality of the animal ethanol lowers the core temperature through increased heat loss and/or decreased heat production. Since brown adipose tissue is the only tissue whose main function is to produce heat, we examined whether the ethanol-induced drop in the core temperature is associated with the mitochondrial uncoupling protein (UCP), which is responsible for energy dissipation as heat in brown fat.
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References
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© 1994 Birkhäuser Verlag Basel
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Huttunen, P., Sämpi, M., Myllylä, R. (1994). Ethanol and Brown Adipose Tissue Thermogenesis in Rats Exposed to the Cold: Uncoupling Protein m-RNA. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_17
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DOI: https://doi.org/10.1007/978-3-0348-7429-8_17
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-0348-7431-1
Online ISBN: 978-3-0348-7429-8
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